Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nanaka, Izumi"'
Publikováno v:
Anticancer research. 33(3)
Mutation of the tumor suppressor gene p53 is the most common genetic alteration observed in human tumors. However, the relationship between the mutation point of p53 and the transcriptional specificity is not so obvious. We prepared Saos-2 cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1ada1ca5211595cdf7325a58638cd7b
https://pubmed.ncbi.nlm.nih.gov/23482763
https://pubmed.ncbi.nlm.nih.gov/23482763
Publikováno v:
Current Topics in Ionizing Radiation Research
The tumor suppressor gene p53 plays an important role in determining radiosensitivity. The normal p53 gene product accumulates after exposure to ionizing radiation, and causes growth arrest or promotes cell death through the apoptosis pathway (Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0a48b2bdca7b82db9915b6603fa2fe
http://www.intechopen.com/articles/show/title/radiation-sensitivity-and-transcription-profile-in-various-mutant-p53-cells
http://www.intechopen.com/articles/show/title/radiation-sensitivity-and-transcription-profile-in-various-mutant-p53-cells
Publikováno v:
Anticancer research. 31(6)
Phosphorylation is an important modification involved in the control of p53 activity. We examined the relationship between p53 phosphorylation and cell radiosensitivity. We prepared H1299 cells (p53-null) with various mutations of p53 at three sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a85018db6911245e7229871a3a9eb0f
https://pubmed.ncbi.nlm.nih.gov/21737649
https://pubmed.ncbi.nlm.nih.gov/21737649
Autor:
Kumio, Okaichi, Miwa, Ide-Kanematsu, Nanaka, Izumi, Naoko, Morita, Yutaka, Okumura, Makoto, Ihara
Publikováno v:
Anticancer research. 28(5A)
Mutation of p53 is the most common genetic alteration observed in human tumours and is reported to lead to variations in cell radiosensitivity. However, the relationship between the mutation point and the degree of radiosensitivity is unclear. Saos-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1bc41881c23560bc2a99c6102c8960c
https://pubmed.ncbi.nlm.nih.gov/19035295
https://pubmed.ncbi.nlm.nih.gov/19035295