Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nanae Harashima"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127386 (2015)
Death signaling provided by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can induce death in cancer cells with little cytotoxicity to normal cells; this cell death has been thought to involve caspase-dependent apoptosis. Reac
Externí odkaz:
https://doaj.org/article/6d03794a58d84d41861700f05e51a634
Autor:
Kazumasa Sekihara, Nanae Harashima, Miki Tongu, Yukihisa Tamaki, Nobue Uchida, Taisuke Inomata, Mamoru Harada
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78772 (2013)
Hyperthermia (HT) improves the efficacy of anti-cancer radiotherapy and chemotherapy. However, HT also inevitably evokes stress responses and increases the expression of heat-shock proteins (HSPs) in cancer cells. Among the HSPs, HSP70 is known as a
Externí odkaz:
https://doaj.org/article/94a8f7f066c84ee18b43d762da26e9f9
TRAIL and agonistic death receptor-specific antibodies can induce apoptosis in cancer cells with little cytotoxicity to normal cells. To improve TRAIL-induced antitumor effects, we tested its effectiveness in combination with pifithrin (PFT)-μ, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544f74a0f274b10892c9ddb9b8687ff5
https://doi.org/10.1158/1535-7163.c.6535953
https://doi.org/10.1158/1535-7163.c.6535953
PDF file - 94K, Expression of DR4 and DR5 on human panreatic cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff9c1789ee394d86686deb64e0c11db
https://doi.org/10.1158/1535-7163.22498725.v1
https://doi.org/10.1158/1535-7163.22498725.v1
Autor:
Richard W. Childs, Michael I. Lerman, W. Marston Linehan, Ramaprasad Srinivasan, Hisayuki Yokoyama, Nanae Harashima, Yoshiyuki Takahashi, Quinn Weisman, Susan Doh, Claire Scrivani, Elena Cherkasova
Example of gating strategy to identify peptide and tumor reactive T cells stimulated from healthy donors: analysis of TM1 peptide stimulated CTLs from donor 4 is shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0322e3fdde6e39f277445700a2f773
https://doi.org/10.1158/0008-5472.22413530
https://doi.org/10.1158/0008-5472.22413530
Autor:
Richard W. Childs, Michael I. Lerman, W. Marston Linehan, Ramaprasad Srinivasan, Hisayuki Yokoyama, Nanae Harashima, Yoshiyuki Takahashi, Quinn Weisman, Susan Doh, Claire Scrivani, Elena Cherkasova
Supplemental Figure Legend for Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597f3891e339b112339084a1f48e6486
https://doi.org/10.1158/0008-5472.22413527.v1
https://doi.org/10.1158/0008-5472.22413527.v1
Autor:
Richard W. Childs, Michael I. Lerman, W. Marston Linehan, Ramaprasad Srinivasan, Hisayuki Yokoyama, Nanae Harashima, Yoshiyuki Takahashi, Quinn Weisman, Susan Doh, Claire Scrivani, Elena Cherkasova
The data of qPCR of cDNA from normal tissues using CT-RCC-Env and CT-RCC-8 specific primers are shown as copies of CT-RCC-Env and CT-RCC-8 transcripts relative to GAPDH X10 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239ff4043fb93e1038c6bb7b46fe623c
https://doi.org/10.1158/0008-5472.22413524
https://doi.org/10.1158/0008-5472.22413524
Autor:
Yuichi Iida, Mamoru Harada, Yoshihiro Komohara, Takanobu Motoshima, Masatoshi Eto, Nanae Harashima
Publikováno v:
Cancer Science
Immune checkpoint blockade is a promising anticancer therapy, but must be used in combination with other anticancer therapies to increase its therapeutic efficacy. Cyclophosphamide (CP) is a chemotherapeutic drug that shows immune‐modulating effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a287f4b4ff05f76ef53c15de4c69579e
https://doi.org/10.1111/cas.13337
https://doi.org/10.1111/cas.13337
Publikováno v:
Oncotarget
Cancer cells develop resistance to therapy by adapting to hypoxic microenvironments, and hypoxia-inducible factors (HIFs) play crucial roles in this process. We investigated the roles of HIF-1α and HIF-2α in cancer cell death induced by tumor necro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84e71d956ed0d42b0a519bc3ce35f4f
http://ir.lib.shimane-u.ac.jp/44978
http://ir.lib.shimane-u.ac.jp/44978
Autor:
Mamoru Harada, Marco A. De Velasco, Koichi Sugimoto, Hirotsugu Uemura, Nanae Harashima, Nobutaka Shimizu, Kazuhiro Yoshimura, Takafumi Minami, Naoki Matsumura, Masahiro Nozawa
Publikováno v:
International Immunopharmacology. 44:197-202
Hypoxic tumor microenvironment makes cancer cells to be therapy-resistant and hypoxia-inducing factors (HIFs) play a central role in hypoxic adaptation. Especially, renal cell carcinoma (RCC) is often associated with von Hippel-Lindau (VHL) gene muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32e0f91206aea29bdfbaf01ddc7eedd
https://doi.org/10.1016/j.intimp.2017.01.014
https://doi.org/10.1016/j.intimp.2017.01.014