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Publikováno v:
Organic letters.
The first diastereoselective synthesis of trisubstituted cubanes was achieved using a chiral auxiliary. To establish chirality within the cubane skeleton, at least three substituents must be introduced at the appropriate positions. Ready conversion o
Publikováno v:
Israel Journal of Chemistry. 61:380-386
Cubane, a hexahedral hydrocarbon, can be converted into an asymmetric molecule with a minimum of three substituents. The resulting chiral cubane can be used as a pharmacophore or a chiral ligand. Starting from the cubane carboxamide, the 1,2,3-substi
Autor:
Yumi Kato, Mei Harada, Seijiro Matsubara, Masanobu Uchiyama, Nana Yoshino, Atsuya Muranaka, Thibaud Mabit, Yuuya Nagata, Craig M. Williams
Publikováno v:
Organic Letters. 22:4083-4087
In the hexahedral hydrocarbon cubane, replacing hydrogen with other atoms at three positions within any one of the internal tetrahedrons can conceptually lead to the formation of a unique class of chiral molecules. In pursuit of this endeavor, we pre
Publikováno v:
HETEROCYCLES. 103:769