Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nana Yaw Osei-Owusu"'
Autor:
Andrew R. Crowley, Nana Yaw Osei-Owusu, Gillian Dekkers, Wenda Gao, Manfred Wuhrer, Diogo M. Magnani, Keith A. Reimann, Seth H. Pincus, Gestur Vidarsson, Margaret E. Ackerman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering e
Externí odkaz:
https://doaj.org/article/624dbe4963b94790af2f76bded8b1288
Autor:
LI Kaodui, Vincent Nana Yaw Osei-Owusu
the study’s objective was to assess the impact of human resource cost thus staff cost on profitability of firms. The scope of the study was listed companies on Ghana Stock Exchange and it selected 42 listed companies as its sample for a period five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71740122f740f8b0b2b560102971ad2b
Autor:
Franco Pissani, Nana Yaw Osei-Owusu, Katrin Ehrhardt, Eric P. Brown, Hartmut Hengel, Hendrik Streeck, Vladimir Temchura, Ghulam Nabi, Klaus Überla, Drew Hannaman, Michael Storcksdieck genannt Bonsmann, Matthias Tenbusch, Margaret E. Ackerman, Thomas Niezold
Publikováno v:
The Journal of Immunology. 195:4861-4872
The importance of Fc-dependent effector functions of Abs induced by vaccination is increasingly recognized. However, vaccination of mice against HIV envelope (Env) induced a skewed Th cell response leading to Env-specific Abs with reduced effector fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5b4300f21e5cdcc276c17263b2ecb3
https://doi.org/10.4049/jimmunol.1501377
https://doi.org/10.4049/jimmunol.1501377
Autor:
Mangala Rao, Ying N. Chan, Galit Alter, Nana Yaw Osei-Owusu, Genoveffa Franchini, Alison E. Mahan, Erica Normandin, Jennifer I. Lai, Margaret E. Ackerman, Eric P. Brown, Monica Vaccari
Publikováno v:
Journal of Immunological Methods. 425:27-36
Glycosylation of the Fc domain is an important driver of antibody effector function. While assessment of antibody glycoform compositions observed across total plasma IgG has identified differences associated with a variety of clinical conditions, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3595db8e186bed8d493bd1036fa1ea9
Autor:
Margaret E. Ackerman, Galit Alter, Andrew R. Crowley, James H. Kappel, Austin W. Boesch, Thach H. Chu, Alison E. Mahan, Nana Yaw Osei-Owusu
Publikováno v:
Biotechnology and bioengineering. 115(5)
As antibodies continue to gain predominance in drug discovery and development pipelines, efforts to control and optimize their activity in vivo have matured to incorporate sophisticated abilities to manipulate engagement of specific Fc binding partne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed559166066915a8f144958df4516cd
https://pubmed.ncbi.nlm.nih.gov/29315477
https://pubmed.ncbi.nlm.nih.gov/29315477
Publikováno v:
mAbs
Non-human primate (NHP) studies are often an essential component of antibody development efforts before human trials. Because the efficacy or toxicity of candidate antibodies may depend on their interactions with Fcγ receptors (FcγR) and their resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f04ee12ff5ea0b35e114b659619e91
https://pubmed.ncbi.nlm.nih.gov/28055295
https://pubmed.ncbi.nlm.nih.gov/28055295
Autor:
Rebecca A. Howell, Nana Yaw Osei-Owusu, Andrew R. Crowley, Ying N. Chan, Margaret E. Ackerman, Joshua W. Eckman, Caitlyn H. Linde, Isaac Zentner, Ali Emileh, Joern E. Schmitz, Samantha L. Finstad, Sarah L. Cocklin, Simon Cocklin, Austin W. Boesch, Adam R. Miles, Galit Alter
Indian rhesus macaques (Macaca mulatta) are routinely used in preclinical studies to evaluate therapeutic Abs and candidate vaccines. The efficacy of these interventions in many cases is known to rely heavily on the ability of Abs to interact with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a3dc0783f3de9d68f49fb2534a8c9c
https://europepmc.org/articles/PMC5026948/
https://europepmc.org/articles/PMC5026948/
Autor:
Nana Yaw Osei-Owusu, Sarah L. Cocklin, Ying Chan, Austin W. Boesch, Joern E. Schmitz, Margaret E. Ackerman
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 71:66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::533135cb3401f69f32299e1a9270d7ce
https://doi.org/10.1097/01.qai.0000479567.53894.e8
https://doi.org/10.1097/01.qai.0000479567.53894.e8
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f0ca2845a8fa6e837ded95add93e37
https://doi.org/10.1096/fasebj.26.1_supplement.1112.5
https://doi.org/10.1096/fasebj.26.1_supplement.1112.5
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf28a1255ca1032bed8fc98a1b5c5ff7
https://doi.org/10.1096/fasebj.25.1_supplement.913.4
https://doi.org/10.1096/fasebj.25.1_supplement.913.4