Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nana Takenaka"'
Autor:
Megumi Yokomizo-Goto, Nana Takenaka-Ninagawa, Chengzhu Zhao, Clémence Kiho Bourgeois Yoshioka, Mayuho Miki, Souta Motoike, Yoshiko Inada, Denise Zujur, William Theoputra, Yonghui Jin, Junya Toguchida, Makoto Ikeya, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Ullrich congenital muscular dystrophy (UCMD) is caused by a deficiency in type 6 collagen (COL6) due to mutations in COL6A1, COL6A2, or COL6A3. COL6 deficiency alters the extracellular matrix structure and biomechanical properties
Externí odkaz:
https://doaj.org/article/f340ceaf0581411496358769fb395f06
Autor:
Clémence Kiho Bourgeois Yoshioka, Nana Takenaka-Ninagawa, Megumi Goto, Mayuho Miki, Daiki Watanabe, Masamichi Yamamoto, Tomoki Aoyama, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is an incurable neuromuscular disease leading to progressive skeletal muscle weakness and fatigue. Cell transplantation in murine models has shown promise in supplementing the lack of the dystroph
Externí odkaz:
https://doaj.org/article/c8652efa539f471d8520c99fa9124f5a
Autor:
Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai, Hidemi Kurihara, Makoto Ikeya
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) lineage under xeno-free conditions and evaluated their in vivo func
Externí odkaz:
https://doaj.org/article/4f3d037871344649b4422fc8b516e401
Autor:
Nana Takenaka-Ninagawa, Jinsol Kim, Mingming Zhao, Masae Sato, Tatsuya Jonouchi, Megumi Goto, Clémence Kiho Bourgeois Yoshioka, Rukia Ikeda, Aya Harada, Takahiko Sato, Makoto Ikeya, Akiyoshi Uezumi, Masashi Nakatani, Satoru Noguchi, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background Mesenchymal stromal cells (MSCs) function as supportive cells on skeletal muscle homeostasis through several secretory factors including type 6 collagen (COL6). Several mutations of COL6A1, 2, and 3 genes cause Ullrich congenital
Externí odkaz:
https://doaj.org/article/8208615de2514f5b8decc05ee6e873df
Autor:
Aya Harada, Megumi Goto, Atsuya Kato, Nana Takenaka-Ninagawa, Akito Tanaka, Satoru Noguchi, Makoto Ikeya, Hidetoshi Sakurai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Collagen VI is distributed in the interstitium and is secreted mainly by mesenchymal stromal cells (MSCs) in skeletal muscle. Mutations in COL6A1-3 genes cause a spectrum of COL6-related myopathies. In this study, we performed a systemic transplantat
Externí odkaz:
https://doaj.org/article/e107aff9d8cc4e0b97962fd95c16cce6
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104462 (2014)
We recently characterized DahlS.Z-Leprfa/Leprfa (DS/obese) rats, derived from a cross between Dahl salt-sensitive rats and Zucker rats, as a new animal model of metabolic syndrome (MetS). Although the phenotype of DS/obese rats is similar to that of
Externí odkaz:
https://doaj.org/article/6cf910974d664aa197f5b0c6e81b2b3b
Publikováno v:
The Japanese Journal of Rehabilitation Medicine. 59:1020-1025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b82ecb94c0712d156ac7f51fffd82e
https://doi.org/10.2490/jjrmc.59.1020
https://doi.org/10.2490/jjrmc.59.1020
Autor:
Yuki Ashida, Koichi Himori, Nao Tokuda, Azuma Naito, Nao Yamauchi, Nana Takenaka-Ninagawa, Yoshitsugu Aoki, Hidetoshi Sakurai, Takashi Yamada
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C885-C895
The mechanisms underlying the disruption of excitation-contraction (EC) coupling in dystrophin-deficient muscles are not well understood. Here, using animal models for Duchenne muscular dystrophies (DMD), we show a Ca2+-dependent protease (calpain-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3456a3e97ac98d79c372c2bbf937d7db
https://doi.org/10.1152/ajpcell.00163.2022
https://doi.org/10.1152/ajpcell.00163.2022
Autor:
Nana Takenaka-Ninagawa, Satoru Takayama, Masanori Nakasa, Makoto Ikeya, Takahiko Sato, Yumi Nakamura, Minas Nalbandian, Miki Nagai, Yuta Ito, Akitsu Hotta, Mingming Zhao, Atsutoshi Tazumi, Akira Watanabe, Hidetoshi Sakurai
Publikováno v:
Stem Cell Reports
Summary Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle-wasting disease caused by DYSTROPHIN deficiency. Cell therapy using muscle stem cells (MuSCs) is a potential cure. Here, we report a differentiation method to generate fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98471cfa5b01a3c21f8bc13826c45e8b
http://europepmc.org/articles/PMC7363940
http://europepmc.org/articles/PMC7363940
Publikováno v:
Current Physical Medicine and Rehabilitation Reports. 8:17-29
This paper reviews the enhanced therapeutic effects of rehabilitation and regenerative medicine toward Duchenne muscular dystrophy. Duchenne muscular dystrophy (DMD) is one of the most severe forms of muscle disorders. Muscle in DMD patients is extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bafc8d69fbf011d4b970cdec764555e5
https://doi.org/10.1007/s40141-019-00255-2
https://doi.org/10.1007/s40141-019-00255-2