Inhibition of non-canonical NF-κB signaling suppresses periodontal inflammation and bone loss

Autor: Tsukasa Aoki, Fumitaka Hiura, Aonan Li, Nan Yang, Nana Takakura-Hino, Satoru Mukai, Miho Matsuda, Fusanori Nishimura, Eijiro Jimi

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Periodontal disease is an infectious disease that affects many people worldwide. Disease progression destroys the alveolar bone and causes tooth loss. We have previously shown that alymphoplasia (aly/aly) mice harboring a loss-of-function mutation in

Externí odkaz: https://doaj.org/article/4b93d59247924d6b8bfa6919605f0ab6

Bif‐1/Endophilin B1/SH3GLB1 regulates bone homeostasis

Autor: Jing Gao, Miho Matsuda, Kenshi Maki, Nana Takakura, Yoshinori Takahashi, Shoichiro Kokabu, Yukihiko Tamura, Yuna Hirohashi, Kenya Touyama, Yuko Fujita, Yui Harada, Masud Khan, Eijiro Jimi, Takuma Matsubara, Kazuhiro Aoki, Hisataka Yasuda, Fumitaka Hiura, Koji Watanabe, Kayo Mori

Publikováno v: Journal of Cellular Biochemistry. 120:18793-18804

Skeletal tissue homeostasis is maintained via the balance of osteoclastic bone resorption and osteoblastic bone formation. Autophagy and apoptosis are essential for the maintenance of homeostasis and normal development in cells and tissues. We found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4860ee37563a178ee85fd749b9f4e4ad
https://doi.org/10.1002/jcb.29193

The Role of NF-κB in Physiological Bone Development and Inflammatory Bone Diseases: Is NF-κB Inhibition 'Killing Two Birds with One Stone'?

Autor: Eijiro Jimi, Shizu Hirata-Tsuchiya, Nana Takakura, Fumitaka Hiura, Ichiro Nakamura

Publikováno v: Cells

Nuclear factor-κB (NF-κB) is a transcription factor that regulates the expression of various genes involved in inflammation and the immune response. The activation of NF-κB occurs via two pathways: inflammatory cytokines, such as TNF-α and IL-1β

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1580dc2130e8dcc4d8a388ac2a9f14
https://pubmed.ncbi.nlm.nih.gov/31847314

Effect of Bioactive Glass-Based Root Canal Sealer on the Incidence of Postoperative Pain after Root Canal Obturation

Autor: Chiaki Kitamura, Atsushi Matsuyama, Hirotake Miyahara, Nana Takakura, Miki Ichimaru-Suematsu, Masataka Fujimoto, Kaori Hanada-Miyahara, Hiroki Miura, Ayako Washio, Takahiko Morotomi, Eiichi Akao, Shinji Yoshii, Kazumasa Murata

Publikováno v: International Journal of Environmental Research and Public Health
Volume 17
Issue 23
International Journal of Environmental Research and Public Health, Vol 17, Iss 8857, p 8857 (2020)

The purpose of this study is to evaluate the effect of a bioactive glass-based root canal sealer, Nishika Canal Sealer BG (CS-BG), on the incidence of postoperative pain (PP) after root canal obturation (RCO). Eleven dentists performed pulpectomy or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f8cc6036bdf55dde6bc39b1abb2b31
https://doi.org/10.3390/ijerph17238857