Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Nana Kawasaki"'
Publikováno v:
Cells, Vol 13, Iss 16, p 1369 (2024)
Neurite outgrowth is a crucial process for organizing neuronal circuits in neuronal development and regeneration after injury. Regenerative failure in the adult mammalian central nervous system (CNS) is attributed to axonal growth inhibitors such as
Externí odkaz:
https://doaj.org/article/21a53092765d49f1829a0cfabe8cb85a
Autor:
Heng Wei, Chie Naruse, Daisuke Takakura, Kazushi Sugihara, Xuchi Pan, Aki Ikeda, Nana Kawasaki, Masahide Asano
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundBeta-1,4-galactosyltransferase-3 (B4GALT3) belongs to the family of beta-1,4-galactosyltransferases (B4GALTs) and is responsible for the transfer of UDP-galactose to terminal N-acetylglucosamine. B4GALT3 is differentially expressed in tumor
Externí odkaz:
https://doaj.org/article/925875432c9542aaadcffdea33df856d
Autor:
Daisuke Takakura, Shoko Ohashi, Noritoshi Kobayashi, Motohiko Tokuhisa, Yasushi Ichikawa, Nana Kawasaki
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to improve the existing cancer biomarkers, and help to assess metastasis risks, and therapeutic effects. We developed a targeted O-glycoproteomics method using serum
Externí odkaz:
https://doaj.org/article/03d138c1794e4268b1b706c478a2f799
Autor:
Sofia S. Guimaraes Koch, Robin Thorpe, Nana Kawasaki, Marie-Paule Lefranc, Sarel Malan, Andrew C.R. Martin, Gilles Mignot, Andreas Plückthun, Menico Rizzi, Stephanie Shubat, Karin Weisser, Raffaella Balocco
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Appropriate nomenclature for all pharmaceutical substances is important for clinical development, licensing, prescribing, pharmacovigilance, and identification of counterfeits. Nonproprietary names that are unique and globally recognized for all phar
Externí odkaz:
https://doaj.org/article/188d9521e50d420394fc6aabfed2537e
Autor:
Kazuyuki Togo, Hayato Fukusumi, Tomoko Shofuda, Hiroshi Ohnishi, Hiroyuki Yamazaki, Mariko Kato Hayashi, Nana Kawasaki, Nobuyuki Takei, Takanobu Nakazawa, Yumiko Saito, Kousuke Baba, Hitoshi Hashimoto, Yuko Sekino, Tomoaki Shirao, Hideki Mochizuki, Yonehiro Kanemura
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract The generation of mature synaptic structures using neurons differentiated from human-induced pluripotent stem cells (hiPSC-neurons) is expected to be applied to physiological studies of synapses in human cells and to pathological studies of
Externí odkaz:
https://doaj.org/article/b05368a3e53c47ce9dff358d956e3092
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract N-glycosylation of glycoproteins, a major post-translational modification, plays a crucial role in various biological phenomena. In central nervous systems, N-glycosylation is thought to be associated with differentiation and regeneration; h
Externí odkaz:
https://doaj.org/article/1b5fad1276fc47159531affe4d74a5f9
Autor:
Yuko Nagai, Hiromi Nakao, Aya Kojima, Yuka Komatsubara, Yuki Ohta, Nana Kawasaki, Nobuko Kawasaki, Hidenao Toyoda, Toshisuke Kawasaki
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 508 (2021)
We developed two human-induced pluripotent stem cell (hiPSC)/human embryonic stem cell (hESC)-specific glycan-recognizing mouse antibodies, R-10G and R-17F, using the Tic (JCRB1331) hiPSC line as an antigen. R-10G recognizes a low-sulfate keratan sul
Externí odkaz:
https://doaj.org/article/39f2e363f2294501929177e924d200d7
Autor:
Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Post-translational modifications, such as glycosylation and sialylation, are thought to confer disease modifying effects on autoimmune-associated antibodies, including anti-citrullinated protein antibodies in rheumatoid arthritis. Here the authors sh
Externí odkaz:
https://doaj.org/article/626de5323ebb454892d4e77327d0fdec
Autor:
Motohiro Nonaka, Shogo Matsumoto, Bruce Yong Ma, Hiroshi Kido, Nana Kawasaki, Nobuko Kawasaki, Toshisuke Kawasaki
Publikováno v:
Applied Sciences, Vol 10, Iss 8, p 2687 (2020)
A class of glycoproteins such as carcinoembryonic antigen (CEA)/CEA-related cell adhesion molecule 1(CEACAM1), CD26 (DPPIV), and mac-2 binding protein (Mac-2BP) harbor tumor-associated glycans in colorectal cancer. In this study, we identified type I
Externí odkaz:
https://doaj.org/article/631bb46f81394da0b53185f2dbb76542
Autor:
Haruhiko Fujihira, Yuki Masahara-Negishi, Masaru Tamura, Chengcheng Huang, Yoichiro Harada, Shigeharu Wakana, Daisuke Takakura, Nana Kawasaki, Naoyuki Taniguchi, Gen Kondoh, Tadashi Yamashita, Yoko Funakoshi, Tadashi Suzuki
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006696 (2017)
The cytoplasmic peptide:N-glycanase (Ngly1 in mammals) is a de-N-glycosylating enzyme that is highly conserved among eukaryotes. It was recently reported that subjects harboring mutations in the NGLY1 gene exhibited severe systemic symptoms (NGLY1-de
Externí odkaz:
https://doaj.org/article/07acc041e0744c58a9504e19583bc30f