Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nan-nan Chu"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Etomidate is a sedative and hypnotic drug through intravenous administration that act on the central nervous system through GABA (Gamma-Amino Butyric Acid) receptors, which is widely used in anesthesia induction and maintenance and long-term
Externí odkaz:
https://doaj.org/article/0a3d03a0ff28481ebf9b91385f4939d6
Autor:
Nan-Nan, Chu, Kai, Huang, Lin-Ling, Que, Ying, Ding, Xiang-Hong, Gu, Lin, Zhang, Jia-Kun, Wang, Xiao-Ping, Chen, Zhan-Guo, Sun, Qing, He
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 47:509-521
101BHG-D01 nasal spray is the first novel long-acting cholinergic M receptor antagonist under development to treat rhinorrhea in rhinitis. This first-in-human study aimed to evaluate the safety, tolerability, and pharmacokinetics of 101BHG-D01 nasal
Autor:
Jiangdian Wang, Nan-Nan Chu, Xue-Ning Li, Guoqin Wang, Hong-Rong Xu, Mengjie Yang, Fei Yuan, Wei-Li Chen
Publikováno v:
Clinical Therapeutics. 37:462-472
Purpose The primary aim of this study was to evaluate whether there was clinically significant pharmacokinetic (PK) interaction between finasteride and tamsulosin in healthy Chinese male subjects. Methods This was an open-label, randomized, 3-period,
Publikováno v:
Clinical Drug Investigation. 2012, Vol. 32 Issue 12, p791-798. 8p.
Publikováno v:
Clinical Drug Investigation. 2009, Vol. 29 Issue 7, p451-457. 7p. 2 Charts, 1 Graph.
Publikováno v:
Clinical drug investigation. 32(12)
Ezetimibe/simvastatin combination tablet has been approved for the treatment of high low-density lipoprotein cholesterol (LDL-C) levels in patients with primary hypercholesterolaemia or mixed hypercholesterolaemia as adjunctive therapy to diet, when
Publikováno v:
Pharmaceutical biology. 48(8)
Lansoprazole is a gastric proton-pump inhibitor and has been demonstrated to be effective in the treatment of various peptic diseases. The effects of CYP2C19 activity on the pharmacokinetics of lansoprazole and its active metabolites in Chinese subje
Publikováno v:
Clinical therapeutics. 32(3)
Background: Cross-study comparisons suggest that systemic exposure (AUC) to rosuvastatin calcium, a 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitor, may be ~2-fold higher in Asian subjects living in Asian countries than in white subjects li
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(27)
A liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed for the determination of matrine in human plasma extracted by isopropanol:ethyl acetate (v/v, 5:95). Rapid chromatographic separation was achieved in the mobile phase co
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 45(4)
A rapid and simple liquid chromatographic-tandem mass spectrometric (LC/MS/MS) method was developed and validated for the simultaneous determination of desloratadine and its active metabolite 3-hydroxydesloratadine concentrations in human plasma. Aft