Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Nan‐Sheng Li"'
Autor:
Sunita Maharjan, Howard Gamper, Yuka Yamaki, Thomas Christian, Robert Y. Henley, Nan-Sheng Li, Takeo Suzuki, Tsutomu Suzuki, Joseph A. Piccirilli, Meni Wanunu, Erin Seifert, Douglas C. Wallace, Ya-Ming Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Human mitochondrial tRNAs (mt-tRNAs), critical for mitochondrial biogenesis, are frequently associated with pathogenic mutations. These mt-tRNAs have unusual sequence motifs and require post-transcriptional modifications to stabilize their f
Externí odkaz:
https://doaj.org/article/6beaaf5507164908a32932465f77b163
Publikováno v:
ACS Omega, Vol 8, Iss 35, Pp 31941-31945 (2023)
Externí odkaz:
https://doaj.org/article/bccca0a743414b299e89c7b024051d5e
Autor:
David J Hosfield, Sandra Weber, Nan-Sheng Li, Madline Sauvage, Carstyn F Joiner, Govinda R Hancock, Emily A Sullivan, Estelle Ndukwe, Ross Han, Sydney Cush, Muriel Lainé, Sylvie C Mader, Geoffrey L Greene, Sean W Fanning
Publikováno v:
eLife, Vol 11 (2022)
Chemical manipulation of estrogen receptor alpha ligand binding domain structural mobility tunes receptor lifetime and influences breast cancer therapeutic activities. Selective estrogen receptor modulators (SERMs) extend estrogen receptor alpha (ER
Externí odkaz:
https://doaj.org/article/a9802c2206974ca0b24d086125724f5f
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacab74dece354d1697fcaf0aa70d89d
https://doi.org/10.1080/15257770.2023.2218421
https://doi.org/10.1080/15257770.2023.2218421
Autor:
Benjamin Weissman, Şölen Ekesan, Hsuan-Chun Lin, Shahbaz Gardezi, Nan-Sheng Li, Timothy J. Giese, Erika McCarthy, Michael E. Harris, Darrin M. York, Joseph A. Piccirilli
Publikováno v:
Journal of the American Chemical Society. 145:2830-2839
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe43c0c6bfd4448937331a2eff2d7535
https://doi.org/10.1021/jacs.2c10079
https://doi.org/10.1021/jacs.2c10079
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 42:538-546
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b4da2960a7acd29d46a322098a09362
https://doi.org/10.1080/15257770.2023.2166064
https://doi.org/10.1080/15257770.2023.2166064
Publikováno v:
The Journal of Organic Chemistry. 86:13231-13244
Oligoribonucleotides containing a photocaged 2'-amino-5'-S-phophorothiolate linkage have potential applications as therapeutic agents and biological probes to investigate the RNA structure and function. We envisioned that oligoribonucleotides contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb404b38cc1586d58224fd7ba7e9a3f
https://doi.org/10.1021/acs.joc.1c01059
https://doi.org/10.1021/acs.joc.1c01059
Autor:
David J Hosfield, Sandra Weber, Nan-Sheng Li, Madline Sauvage, Carstyn F Joiner, Govinda R Hancock, Emily A Sullivan, Estelle Ndukwe, Ross Han, Sydney Cush, Muriel Lainé, Sylvie C Mader, Geoffrey L Greene, Sean W Fanning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553bfbebeafccfa949ba16a598c9c124
https://doi.org/10.7554/elife.72512.sa2
https://doi.org/10.7554/elife.72512.sa2
Autor:
Nan-Sheng Li, Joseph A. Piccirilli, David A. Hiller, Sunitha Nallur, Scott A. Strobel, Brian F. Dunican
Publikováno v:
Biochemistry
The bacterial toxin RelE cleaves mRNA in the ribosomal A site. Although it shares a global fold with other microbial RNases, the active site contains several positively charged residues instead of histidines and glutamates that are typical of ribonuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bed7720597b1e432748b441bfb35691
https://doi.org/10.1021/acs.biochem.9b01047
https://doi.org/10.1021/acs.biochem.9b01047
Autor:
Joseph A. Piccirilli, Darrin M. York, Saieesh A Rao, Abir Ganguly, Benjamin P. Weissman, Steven A. Benner, Shuichi Hoshika, Timothy J. Giese, Nan-Sheng Li
Publikováno v:
Nature chemistry
The Varkud satellite ribozyme catalyses site-specific RNA cleavage and ligation, and serves as an important model system to understand RNA catalysis. Here, we combine stereospecific phosphorothioate substitution, precision nucleobase mutation and lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce95e108ab1414012062964d39f2d33
http://europepmc.org/articles/PMC7389185
http://europepmc.org/articles/PMC7389185