Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Namrta Bhardwaj"'
Autor:
John S. Andrews, Subhash C. Annedi, Suman Rakhit, Shawn Maddaford, Jailall Ramnauth, Joanne Patman, Paul Renton, Namrta Bhardwaj
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2540-2544
A series of substituted 2-aminobenzothiazole compounds have been synthesized and evaluated as nitric oxide synthase (NOS) inhibitors. Compound 14 shows activity in the nM range and is selective for the human neuronal NOS isoform. We have also evaluat
Publikováno v:
Canadian Journal of Chemistry. 80:141-147
The syntheses of 3,6-dineopentoxyphthalonitrile and 3,4,5,6-tetraneopentoxyphthalonitrile are described. Condensation of these phthalonitriles with nickel chloride in N,N-dimethylaminoethanol yielded 1,4,8,11,15,18,22,25-octaneopentoxyphthalocyaninat
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :484-490
4,5-Dineopentoxyphthalonitrile was prepared from catechol and neopentyl tosylate in three steps. Condensation of this substituted phthalonitrile with lithium metal in 1-pentanol led to 2,3,9,10,16,17,23,24-octaneopentoxyphthalocyanine. Lithiation in
Publikováno v:
ChemInform. 35
The palladium-catalyzed cyanation of aryl bromides and iodides to the corresponding nitriles occurs at room temperature when tri-t-butylphosphine is used as ligand, Zn(CN) 2 as the cyanide source and Zn dust as a co-catalyst in DMF as solvent. A vari