Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Namjong Choi"'
Autor:
Sarah E. Hochman, Theresa F. Madaline, Samuel C. Wassmer, Emmie Mbale, Namjong Choi, Karl B. Seydel, Richard O. Whitten, Julie Varughese, Georges E. R. Grau, Steve Kamiza, Malcolm E. Molyneux, Terrie E. Taylor, Sunhee Lee, Danny A. Milner, Kami Kim
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
Externí odkaz:
https://doaj.org/article/960f3a82cfed43c3b7f630eaf05343cb
Autor:
Sarah E. Hochman, Theresa F. Madaline, Samuel C. Wassmer, Emmie Mbale, Namjong Choi, Karl B. Seydel, Richard O. Whitten, Julie Varughese, Georges E. R. Grau, Steve Kamiza, Malcolm E. Molyneux, Terrie E. Taylor, Sunhee Lee, Danny A. Milner, Kami Kim
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controve
Externí odkaz:
https://doaj.org/article/5189f1d3b89541a3baa1c8eae4df4826
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98184 (2014)
Compelling data exist that show that normal levels of progranulin (PGRN) are required for successful CNS aging. PGRN production is also modulated by inflammation and infection, but no data are available on the production and role of PGRN during CNS H
Externí odkaz:
https://doaj.org/article/d2f709b5af094e1dbd43ac776233e940
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35115 (2012)
The essential role of progranulin (PGRN) as a neurotrophic factor has been demonstrated by the discovery that haploinsufficiency due to GRN gene mutations causes frontotemporal lobar dementia. In addition to neurons, microglia in vivo express PGRN, b
Externí odkaz:
https://doaj.org/article/b4538317aca04eb3b7c12e414a76b570
Autor:
Georges E. Grau, Kami Kim, Steve Kamiza, Karl B. Seydel, Terrie E. Taylor, Emmie Mbale, Danny A. Milner, Sunhee Lee, Sarah Hochman, Richard O. Whitten, Samuel C. Wassmer, Namjong Choi, Theresa Madaline, Julie Varughese, Malcolm E. Molyneux
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
mBio, Vol 7, Iss 1, p e02068-15 (2016)
mBio, Vol 7, Iss 1, p e02068-15 (2016)
Vol. 6, no. 5, doi:10.1128/mBio.01390-15, 2015. We correct the following errors in our published paper. These do not affect the main findings showing significant intravascular accumulations of monocytes and platelets in the brain tissues of children
Autor:
Jack P. Antel, Qiao Ling Cui, Melissa Cosenza-Nashat, Daniela Krause, Namjong Choi, Sunhee C. Lee, Leonid Tarassishin, Meng Liang Zhao, Hyeon Sook Suh, Avital Bauman, Bryce A. Durafourt
Publikováno v:
The American Journal of Pathology. 179:1360-1372
Tryptophan metabolism by the kynurenine pathway (KP) is important to the pathogenesis of inflammatory, infectious, and degenerative diseases. The 3-hydroxykynurenine (3-HK) branch of the KP is activated in macrophages and microglia, leading to the ge
Autor:
Namjong Choi, Harris Goldstein, Sunhee C. Lee, Hyeon Sook Suh, Melissa Cosenza-Nashat, Randy L. Jirtle, Jeffrey W. Pollard, Meng Liang Zhao, Jiu Feng Li
Publikováno v:
The American Journal of Pathology. 177:2446-2458
Insulin-like growth factor 2 receptor (IGF2R), also known as cation-independent mannose 6-phosphate (M6P) receptor, is a transmembrane glycoprotein localized in the trans-Golgi region and is involved in targeting both M6P-bearing enzymes and IGF2 to
Publikováno v:
Journal of Neuroimmune Pharmacology. 5:521-532
Histone deacetylase inhibitors (HDACi) have been proposed as therapies for certain cancers and as an anti-reservoir therapy for HIV+ individuals with highly active anti-retroviral therapy, yet their roles in glial inflammatory and innate antiviral ge
Autor:
Sunhee C. Lee, Hyeon-Sook Suh, Meng-Liang Zhao, Namjong Choi, Thomas J. Belbin, Celia F. Brosnan
Publikováno v:
Virology. 392:246-259
In the CNS, microglia are the primary targets of HIV infection. In this study, we investigated the effect of activation of the innate antiviral receptors TLR3 and TLR4 on HIV infection of primary human microglia, as well as microglial cell signaling
Autor:
Samuel C. Wassmer, Karl B. Seydel, Terrie E. Taylor, Emmie Mbale, Sunhee Lee, Malcolm E. Molyneux, Steve Kamiza, Georges E. Grau, Danny A. Milner, Richard O. Whitten, Julie Varughese, Sarah Hochman, Namjong Choi, Kami Kim, Theresa Madaline
Publikováno v:
mBio
mBio, Vol 6, Iss 5 (2015)
mBio, Vol 6, Iss 5 (2015)
Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In