Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Namita Chutani"'
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1527 (2023)
A newly discovered chromatin remodeler, MORC2, is a Microrchidia (MORC) family member. MORC2 acts as a chromatin remodeler by binding to the DNA and changing chromatin conformation using its ATPase domain. MORC2 is highly expressed in a variety of hu
Externí odkaz:
https://doaj.org/article/e1fd3c331aab4963a9d6923b32c76c19
Publikováno v:
Biophys Rev
Microrchidia 2 (MORC2) is an emerging chromatin modifier with a role in chromatin remodeling and epigenetic regulation. MORC2 is found to be upregulated in most cancers, playing a significant role in tumorigenesis and tumor metastasis. Recent studies
Autor:
Namita, Chutani, Anjali Kumari, Singh, Rajashekar Varma, Kadumuri, Suresh B, Pakala, Sreenivas, Chavali
Publikováno v:
Journal of Molecular Biology. 434:167664
Chromatin remodelers affect the spatio-temporal dynamics of global gene-expression by structurally modulating and/or reorganizing the chromatin. Microrchidia (MORC) family is a relatively new addition to the four well studied families of chromatin re