Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Namisha Patel"'
Publikováno v:
European Journal of Pharmacology. 341:17-22
In previous experiments, it was demonstrated that systemic or central administration of the nitric oxide synthase (NO synthase) inhibitor, NG-nitro-L-arginine (N-Arg), produced dose-dependent learning impairments in rats in a 14-unit T-maze; and that
Autor:
Namisha Patel, Grant S. Blank, John Hengemihle, Stacie Brzozowski, Dorey Speer, Donald K. Ingram, Edward L. Spangler
Publikováno v:
Experimental Gerontology. 32:707-717
Male Mongolian gerbils ( Meriones unguiculatus ) 14–54 months old ( n = 77) were evaluated in a battery of psychomotor (open field, locomotor, and runwheel activity, rotorod performance) and learning (one-way active avoidance in a straight runway a
Autor:
Dorey Speer, Arnold Brossi, Namisha Patel, Nigel H. Greig, Xue-Feng Pei, Donald K. Ingram, Hiroyuki Ikari, Edward L. Spangler
Publikováno v:
NeuroReport. 6:481-484
A new generation of cholinesterase inhibitors is expected to overcome some limitations of the therapeutic use of anticholinesterases. Phenserine is a long-acting and selective inhibitor of acetylcholinesterase with a preferential brain uptake. We hav
Autor:
Edward L. Spangler, Alicja L. Markowska, Michael Hyman, Dorey Speer, John Hengemihle, Donald K. Ingram, Namisha Patel
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 57(2)
Two strains of the senescence accelerated mouse, P8 and R1,were tested in footshock-motivated passive avoidance (PA; P8, 3-21 months; R1, 3-24 months) and 14-unit T-maze (P8 and R1, 9, and 15 months) tasks. For PA, entry to a dark chamber from a ligh
Autor:
Omoefe Abugo, Chavali Balagopalakrishna, D. Danon, Edward L. Spangler, Joseph M. Rifkind, R.R. Peddada, Namisha Patel, Donald K. Ingram, Dorey Speer
Publikováno v:
Life sciences. 64(4)
Mean cell volume (MCV) of erythrocytes has been reported to increase with age in humans, and to be negatively correlated with memory performance in humans and rats. We evaluated hematological changes in 21-mo old male Fischer 344 rats undergoing a 3-
Autor:
Edward L. Spangler, Qian-Sheng Yu, Donald K. Ingram, Nigel H. Greig, Namisha Patel, Robert C. Meyer
Publikováno v:
Neuroreport. 9(1)
The present study evaluated the interaction of the glutamatergic and acetylcholinergic systems in memory formation, with an overall emphasis on developing multi-system approaches for treating age-related cognitive decline and Alzheimer' s disease. Sp