Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nami Yabuki"'
Autor:
Yoshiyuki Arata, Shigeki Motoyama, Mariko Yano, Tatsuya Ikuno, Shunsuke Ito, Tomochika Matsushita, Akira Takeiri, Yukari Nishito, Nami Yabuki, Hideaki Mizuno, Zenjiro Sampei, Masayuki Mishima, Masaki Honda, Jumpei Kiyokawa, Hiromi Suzuki, Shuichi Chiba, Mitsuyasu Tabo, Chiyomi Kubo
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTTherapeutic antibodies sometimes elicit anti-drug antibodies (ADAs) that can affect efficacy and safety. Engineered antibodies that contain artificial amino acid sequences are potentially highly immunogenic, but this is currently difficult to
Externí odkaz:
https://doaj.org/article/9c8b83e3cca74382a102aa8a0b0f06ad
Autor:
Kazunori Aoki, Yukari Nishito, Noriko Motoi, Yasuhito Arai, Nobuyoshi Hiraoka, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa, Eri Hashimoto, Mina Takahashi, Etsuko Fujii, Takashi Nishizawa, Hironori Fukuda, Kana Ohashi, Kosuke Arai, Yukihiro Mizoguchi, Yukihiro Yoshida, Shun-ichi Watanabe, Makiko Yamashita, Shigehisa Kitano, Hiromi Sakamoto, Yuki Nagata, Risa Mitsumori, Kouichi Ozaki, Shumpei Niida, Yae Kanai, Akiyoshi Hirayama, Tomoyoshi Soga, Toru Maruyama, Keisuke Tsukada, Nami Yabuki, Mei Shimada, Takehisa Kitazawa, Osamu Natori, Noriaki Sawada, Atsuhiko Kato, Teruhiko Yoshida, Kazuki Yasuda, Hideaki Mizuno, Hiroyuki Tsunoda, Atsushi Ochiai
Publikováno v:
Cancer Research Communications.
Resistance to immune-checkpoint blockade remains challenging in patients with non-small cell lung cancer (NSCLC). Tumor-infiltrating leukocyte (TIL) quantity, composition, and activation status profoundly influence responsiveness to cancer immunother
Autor:
Masaki Yamazaki1 yamazakimsk@chugai-pharm.co.jp, Nami Yabuki1,2, Yasunori Suzuki2, Mayumi Ito2, Asuka Ikeda3, Osamu Natori2, Masami Suzuki1, Atsuhiko Kato1
Publikováno v:
Journal of Toxicologic Pathology. 2018, Vol. 31 Issue 3, p213-220. 8p.
Autor:
Yasunori Suzuki, Mayumi Ito, Masaki Yamazaki, Masami Suzuki, Atsuhiko Kato, Asuka Ikeda, Osamu Natori, Nami Yabuki
Publikováno v:
Journal of Toxicologic Pathology
Assessing how gene expression analysis by RNA sequencing (RNA-Seq) correlates to a unique morphology is increasingly necessary, and laser capture microdissection (LCM) is a critical research tool for discovering the genes responsible in a region of i
Autor:
Yukiko Iwasaki, Makoto Okazaki, Mai Okubo, Kazuhiko Yamamoto, Shuji Sumitomo, Hiroshi Kaneko, Satomi Kobayashi, Saeko Yamada, Chikashi Terao, Yasuo Nagafuchi, Nami Yabuki, Sohei Oyama, Shuji Akizuki, Tsuneyo Mimori, Haruka Tsuchiya, Koichiro Ohmura, Ken Yoshida, Kazuyoshi Ishigaki, Yukinori Okada, Ryochi Yoshida, Yuta Kochi, Tomohisa Okamura, Yusuke Takeshima, Mineto Ota, Keigo Setoguchi, Junko Maeda, Nobuhiro Ban, Yusuke Sugimori, Hironori Mutoh, Masato Okada, Daitaro Kurosaka, Keishi Fujio, Hiroaki Hatano, Hirofumi Shoda, Yumi Tsuchida, Haruyuki Yanaoka, Kosuke Matsuki, Hiroyuki Tsunoda, Hajime Yoshifuji, Masahiro Nakano, Harumi Shirai
Publikováno v:
Cell. 184:3006-3021.e17
Summary Genetic studies have revealed many variant loci that are associated with immune-mediated diseases. To elucidate the disease pathogenesis, it is essential to understand the function of these variants, especially under disease-associated condit
Publikováno v:
Genes to Cells. 7:781-789
Background: Understanding of the firing time determination of replication origins in the entire genome will require a genome-wide survey of replication origins and their mapping on chromosomes. A microarray technology was applied to obtain a genome-w
Publikováno v:
Yeast. 18:239-249
The PHO85 gene is a negative regulator of the PHO system in the yeast Saccharomyces cerevisiae and encodes a protein kinase (Pho85) highly homologous to the Cdc28 kinase (Cdc28). Ten cyclin-like proteins are known to interact with Pho85, and combinat
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 2:279-287
Abstract: Rapid degradation of wild-type p53 in the human uterine cervix is induced by the infection of high-risk human papilloma virus (HPV) types 16 and 18. HPV-E6 protein plays a critical role in the poly-ubiquitination of wild-type p53 by mediati
Publikováno v:
Journal of Bacteriology. 181:3886-3889
The final destination of glycosylphosphatidylinositol (GPI)-attached proteins in Saccharomyces cerevisiae is the plasma membrane or the cell wall. Two kinds of signals have been proposed for their cellular localization: (i) the specific amino acid re
Autor:
Hisashi Koga, Akira Kuwano, Ichiro Matsuda, Fumio Endo, Nami Yabuki, Yoshiomi Honda, Tadashi Anan, Chikara Miyamoto, Yoichi Nagata, Hideyuki Saya, Mitsuyoshi Nakao
Publikováno v:
Genes to Cells. 3:751-763
Background Nedd4 is a ubiquitin-protein ligase containing a calcium/lipid-binding domain, multiple WW domains and a C-terminal Hect domain, which is required for both the ubiquitin transfer and the association with E2 ubiquitin-conjugating enzymes. N