Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nametso Kelentse"'
Autor:
Natasha O. Moraka, Wonderful T. Choga, Marea N. Pema, Moses Kudzai Chawawa, Irene Gobe, Margaret Mokomane, Ontlametse T. Bareng, Lynette Bhebhe, Nametso Kelentse, Graceful Mulenga, Molly Pretorius Holme, Terence Mohammed, Catherine K. Koofhethile, Joseph M. Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bnAbs) and evaluate the different HIV-1 Env characteristics that may affect virus neutralization. We analyzed proviral sequences from adu
Externí odkaz:
https://doaj.org/article/34cd02c202c244d98df4161bb39f3c8a
Autor:
Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences f
Externí odkaz:
https://doaj.org/article/8a3484c8f0984aef98f28951e867c1e8
Autor:
Ontlametse T. Bareng, Sekgabo Seselamarumo, Kaelo K. Seatla, Wonderful T. Choga, Blessing Bakae, Dorcas Maruapula, Nametso Kelentse, Natasha O. Moraka, Baitshepi Mokaleng, Patrick T. Mokgethi, Tsotlhe R. Ditlhako, Molly Pretorius-Holme, Mpaphi B. Mbulawa, Refeletswe Lebelonyane, Ebi Celestin Bile, Tendani Gaolathe, Roger Shapiro, Joseph M. Makhema, Shahin Lockman, Max Essex, Vlad Novitsky, Sununguko W. Mpoloka, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 31, Iss , Pp 128-134 (2022)
ABSTRACT: Objectives: There are limited data on the prevalence of doravirine (DOR)-associated drug resistance mutations in people with HIV (PWH) in Botswana. This cross-sectional, retrospective study aimed to explore the prevalence of DOR-associated
Externí odkaz:
https://doaj.org/article/d7a2551a089a442ebde7a8c9782b8357
Autor:
Baitshepi Mokaleng, Wonderful Tatenda Choga, Ontlametse Thato Bareng, Dorcas Maruapula, Doreen Ditshwanelo, Nametso Kelentse, Patrick Mokgethi, Natasha Onalenna Moraka, Modisa Sekhamo Motswaledi, Leabaneng Tawe, Catherine Kegakilwe Koofhethile, Sikhulile Moyo, Matshediso Zachariah, Simani Gaseitsiwe
Publikováno v:
Vaccines, Vol 11, Iss 5, p 1000 (2023)
HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a
Externí odkaz:
https://doaj.org/article/cc5b46af2f8d4f3eb549ce98b15f493f
Autor:
Nametso Kelentse, Sikhulile Moyo, Kesaobaka Molebatsi, Olorato Morerinyane, Shatho Bitsang, Ontlametse T. Bareng, Kwana Lechiile, Tshepo B. Leeme, David S. Lawrence, Ishmael Kasvosve, Rosemary Musonda, Mosepele Mosepele, Thomas S. Harrison, Joseph N. Jarvis, Simani Gaseitsiwe
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1399 (2022)
Cerebrospinal fluid (CSF) viral escape has been poorly described among people with HIV-associated cryptococcal meningitis. We determined the prevalence of CSF viral escape and HIV-1 viral load (VL) trajectories in individuals treated for HIV-associat
Externí odkaz:
https://doaj.org/article/27f6d5b2e87444f6ba0ef039e49c4b42
Autor:
Tuelo Mogashoa, Pinkie Melamu, Serej D Ley, Elizabeth M Streicher, Thato Iketleng, Nametso Kelentse, Lucy Mupfumi, Margaret Mokomane, Botshelo Kgwaadira, Vladimir Novitsky, Ishmael Kasvosve, Sikhulile Moyo, Robin M Warren, Simani Gaseitsiwe
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216306 (2019)
BackgroundMolecular typing of Mycobacterium tuberculosis (M.tb) isolates can inform Tuberculosis (TB) control programs on the relative proportion of transmission driving the TB epidemic. There is limited data on the M. tb genotypes that are circulati
Externí odkaz:
https://doaj.org/article/5ffe4653fbaa4b5290826332ce0afbcc
Autor:
Nametso Kelentse, Sikhulile Moyo, Mompati L. Mogwele, Doreen Ditshwanelo, Baitshepi Mokaleng, Natasha O. Moraka, Kwana Lechiile, Tshepo B. Leeme, David S. Lawrence, Rosemary Musonda, Ishmael Kasvosve, Thomas S. Harrison, Joseph N. Jarvis, Simani Gaseitsiwe
Publikováno v:
Viruses, Vol 12, Iss 12, p 1404 (2020)
HIV-1 compartmentalization in reservoir sites remains a barrier to complete HIV eradication. It is unclear whether there is variation in HIV-1 env and gag between cerebrospinal fluid (CSF) and plasma of individuals with HIV-associated cryptococcal me
Externí odkaz:
https://doaj.org/article/3c0f3b66668a4526ac4d9fc9da4430b7
Autor:
Nametso Kelentse, Sikhulile Moyo, Wonderful T Choga, Kwana Lechiile, Tshepo B Leeme, David S Lawrence, Ishmael Kasvosve, Rosemary Musonda, Mosepele Mosepele, Thomas S Harrison, Joseph N Jarvis, Simani Gaseitsiwe
Publikováno v:
The Journal of antimicrobial chemotherapy.
Objectives We compared the patterns of HIV-1 drug resistance mutations between the CSF and plasma of individuals with HIV-associated cryptococcal meningitis. Methods This is a cross-sectional study of archived CSF and plasma samples collected from AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d72053305783ae66d36d35f7294be9
https://pubmed.ncbi.nlm.nih.gov/36322466
https://pubmed.ncbi.nlm.nih.gov/36322466
Autor:
Simani Gaseitsiwe, Natasha O. Moraka, Mompati Mogwele, Baitshepi Mokaleng, Doreen Ditshwanelo, Ishmael Kasvosve, Nametso Kelentse, David S Lawrence, Tshepo B Leeme, Rosemary Musonda, Joseph N Jarvis, Sikhulile Moyo, Thomas S. Harrison, Kwana Lechiile
Publikováno v:
Viruses, Vol 12, Iss 1404, p 1404 (2020)
Viruses
Volume 12
Issue 12
Viruses
Volume 12
Issue 12
HIV-1 compartmentalization in reservoir sites remains a barrier to complete HIV eradication. It is unclear whether there is variation in HIV-1 env and gag between cerebrospinal fluid (CSF) and plasma of individuals with HIV-associated cryptococcal me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42a175bc645f5883b386cceb78a2539
https://openaccess.sgul.ac.uk/id/eprint/112892/1/viruses-12-01404.pdf
https://openaccess.sgul.ac.uk/id/eprint/112892/1/viruses-12-01404.pdf
Autor:
Thomas S. Harrison, Joseph N Jarvis, Natasha O. Moraka, Rosemary Musonda, Simani Gaseitsiwe, Kwana Lechiile, Ishmael Kasvosve, Mompati Mogwele, Dorcas Maruapula, Kesaobaka Molebatsi, Tshepo B Leeme, David S Lawrence, Sikhulile Moyo, Kaelo K Seatla, Nametso Kelentse, Lerato Esele
Publikováno v:
Medicine
To determine effects of cryptococcal meningitis (CM) on human immunodeficiency virus (HIV)-1C cerebrospinal fluid (CSF) viral escape, CSF/plasma viral discordance, and drug resistance mutation (DRM) discordance between CSF and plasma compartments, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578be15c77a19f4d0fa10c3ffc2c5581
https://pubmed.ncbi.nlm.nih.gov/33031315
https://pubmed.ncbi.nlm.nih.gov/33031315