Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nam Q. Bui"'
Autor:
Stefano Testa, Benjamin D. Hu, Natalie L. Saadeh, Allison Pribnow, Sheri L. Spunt, Gregory W. Charville, Nam Q. Bui, Kristen N. Ganjoo
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 5304-5317 (2021)
Osteosarcoma is the most common primary bone malignancy in both children and adults. Despite introduction of intensive multimodal treatment with chemotherapy and surgery, outcomes are still poor, especially for patients with metastatic disease and ad
Externí odkaz:
https://doaj.org/article/443847c0d3144ddb9618a5e90a32780c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9571 (2023)
Well-differentiated/de-differentiated liposarcoma (WDLPS/DDLPS) is one of the most common histologic subtypes of soft tissue sarcoma (STS); however, treatment options remain limited. WDLPS and DDLPS both exhibit the characteristic amplification of ch
Externí odkaz:
https://doaj.org/article/f4dab013da3d41a3a74d269cb4765459
Autor:
Ted Kim, Nam Q. Bui
Publikováno v:
Cancers, Vol 15, Iss 6, p 1692 (2023)
Soft tissue sarcomas (STS) are a rare, complex, heterogeneous group of mesenchymal neoplasms with over 150 different histological subtypes. Treatments for this malignancy have been especially challenging due to the heterogeneity of the disease and th
Externí odkaz:
https://doaj.org/article/0e71040810cb4af68a226ce7964ab683
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
CIC-DUX4 rearrangements define an aggressive and chemotherapy-insensitive subset of undifferentiated sarcomas. The CIC-DUX4 fusion drives oncogenesis through direct transcriptional upregulation of cell cycle and DNA replication genes. Notably, CIC-DU
Externí odkaz:
https://doaj.org/article/5dc73dadcaad4c37b2a6d4c8be142289
Publikováno v:
Cancer Treatment and Research Communications, Vol 31, Iss , Pp 100562- (2022)
Desmoid tumors are rare soft tissue tumors that can have aggressive infiltrative growth and relapse locally. Desmoid tumors can impact functionality and cause treatment-related morbidity and mortality. Here, the authors review current management stra
Externí odkaz:
https://doaj.org/article/587e27a543d64321a8a5e7cfb9240a63
Autor:
Lawrence Liu, Carina Dehner, Nikhil Grandhi, Yang Lyu, Dana C. Borcherding, John S. A. Chrisinger, Xiao Zhang, Jingqin Luo, Yu Tao, Amanda Parkes, Nam Q. Bui, Elizabeth J. Davis, Mohammed M. Milhem, Varun Monga, Mia Weiss, Brian Van Tine, Angela C. Hirbe
Publikováno v:
Genes, Vol 13, Iss 11, p 1932 (2022)
Background: Perivascular epithelioid cell neoplasms (PEComas) are a diverse family of mesenchymal tumors with myomelanocytic differentiation that disproportionately affect women and can be associated with tuberous sclerosis (TS). Although mTOR inhibi
Externí odkaz:
https://doaj.org/article/fb8f331eadf148069c02a56e2d15b309
Autor:
Stefano Testa, Nam Q. Bui, Gregory W. Charville, Raffi S. Avedian, Robert Steffner, Pejman Ghanouni, David G. Mohler, Kristen N. Ganjoo
Publikováno v:
Cancers, Vol 14, Iss 16, p 3907 (2022)
The initial management of desmoid tumors (DTs) is shifting from surgery towards active surveillance, with systemic and locally ablative treatments reserved for enlarging and/or symptomatic disease. However, it remains unclear which patients would ben
Externí odkaz:
https://doaj.org/article/15284b64882f4dfc84179953d980594f
Publikováno v:
JAAD Case Reports, Vol 6, Iss 5, Pp 447-449 (2020)
Externí odkaz:
https://doaj.org/article/2fb0e63b6d7247468293eeb74e015992
Autor:
Mizuo Ando, Yuki Saito, Guorong Xu, Nam Q. Bui, Kate Medetgul-Ernar, Minya Pu, Kathleen Fisch, Shuling Ren, Akihiro Sakai, Takahito Fukusumi, Chao Liu, Sunny Haft, John Pang, Adam Mark, Daria A. Gaykalova, Theresa Guo, Alexander V. Favorov, Srinivasan Yegnasubramanian, Elana J. Fertig, Patrick Ha, Pablo Tamayo, Tatsuya Yamasoba, Trey Ideker, Karen Messer, Joseph A. Califano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In tumours aberrant epigenetic modifications can alter the transcriptional state. Here, the authors identify a common tumour-specific shift to transcriptional repression associated with DNA methylation and chromatin dysregulation at the transcription
Externí odkaz:
https://doaj.org/article/92171efeb0c747ec87436ef09a8ab860
Publikováno v:
Cancers, Vol 14, Iss 2, p 324 (2022)
Patients with liver-dominant metastatic or primary hepatic soft tissue sarcomas (STS) have poor prognosis. Surgery can prolong survival, but most patients are not surgical candidates, and treatment response is limited with systemic chemotherapy. Live
Externí odkaz:
https://doaj.org/article/6ad60a52824e4047bff3443b2f3b2254