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pro vyhledávání: '"Nam Ho Jeoung"'
Autor:
Nam Ho Jeoung
Publikováno v:
Diabetes & Metabolism Journal, Vol 39, Iss 3, Pp 188-197 (2015)
Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major regulatory step, an irreversible reac
Externí odkaz:
https://doaj.org/article/164cab73b3584528966698ee155369db
Autor:
Chang Joo Oh, Sungmi Park, Joon-Young Kim, Han-Jong Kim, Nam Ho Jeoung, Young-Keun Choi, Younghoon Go, Keun-Gyu Park, In-Kyu Lee
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 855-864 (2014)
Excessive proliferation of vascular smooth muscle cells (VSMCs) and incomplete re-endothelialization is a major clinical problem limiting the long-term efficacy of percutaneous coronary angioplasty. We tested if dimethylfumarate (DMF), an anti-psoria
Externí odkaz:
https://doaj.org/article/62b60a8524904049a28b10708cd970c2
Publikováno v:
Diabetes & Metabolism Journal, Vol 36, Iss 5, Pp 328-335 (2012)
The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes. Although it has been reported that PDC is p
Externí odkaz:
https://doaj.org/article/f688287f80ea4fcbbf88a6c5eb718361
Autor:
Hyeon-Ji Kang, Hyun-Ae Seo, Younghoon Go, Chang Joo Oh, Nam Ho Jeoung, Keun-Gyu Park, In-Kyu Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61411 (2013)
The excessive accumulation of adipocytes contributes to the development of obesity and obesity-related diseases. The interactions of several transcription factors, such as C/EBPβ, PPARγ, C/EBPα, Nrf2, and STAT3, are required for adipogenic differe
Externí odkaz:
https://doaj.org/article/f75ececc4a9449ea99a267ae2f6f5549
Publikováno v:
Journal of Nutritional Science and Vitaminology. 68:79-86
Skeletal muscle plays crucial roles in locomotion, protein reservoir, and maintenance of metabolic homeostasis. Loss of muscle, known as muscle atrophy, causes the metabolic diseases such as type 2 diabetes mellitus, hypertension, and so on. Therefor
Publikováno v:
Journal of Cancer Prevention
Cryptotanshinone is known for its inhibitory activity against tumorigenesis in various human cancer cells. However, exact mechanisms underlying the anticancer effects of cryptotanshinone are not fully elucidated. Here, we propose a plausible molecula
Publikováno v:
Biochemical and Biophysical Research Communications. 558:22-28
Autocrine motility factor (AMF) stimulates the motility of cancer cells via an autocrine route and has been implicated in tumor progression and metastasis. Overexpression of AMF is correlated with the aggressive nature of breast cancer and is negativ
Autor:
Nam Ho Jeoung, Hee Sung Park
Publikováno v:
Biochemical and biophysical research communications. 525(3)
In cell competition, a secreted death signal can determine cell fate. However, the nature of such a signal remains unclear. In this study, conditioned medium from HeLa cells (HeLa CM) inhibited growth of A549 and MCF-7 cells. Through HeLa CM fraction
Autor:
Jae-Han Jeon, Inkyu Lee, Yong Hyun Jeon, Jeong Eun Kim, Woong Kwon, Younghoon Go, Nam Ho Jeoung, Ling He, Hye Jin Ham, Bo Yoon Park, Byung-Gyu Kim, Eun Kyung Yoo, Keun-Gyu Park, Robert A. Harris, Seung Hoi Koo
Publikováno v:
Diabetes. 67:2054-2068
In fasting or diabetes, gluconeogenic genes are transcriptionally activated by glucagon stimulation of the cAMP-protein kinase A (PKA)–CREB signaling pathway. Previous work showed pyruvate dehydrogenase kinase (PDK) inhibition in skeletal muscle in
Publikováno v:
Food Science and Biotechnology. 25:119-124
In this study, we investigated the effects of silymarin (SM) on gluconeogenesis during exercise in rats. After 4 weeks of exercise, blood samples, liver, and skeletal muscle tissues were collected, and the levels of triglycerides (TG), lactate, perox