The impact of food availability on tumorigenesis is evolutionarily conserved

Autor: Sophie Tissot, Lena Guimard, Jordan Meliani, Justine Boutry, Antoine M. Dujon, Jean-Pascal Capp, Jácint Tökölyi, Peter A. Biro, Christa Beckmann, Laura Fontenille, Nam Do Khoa, Rodrigo Hamede, Benjamin Roche, Beata Ujvari, Aurora M. Nedelcu, Frédéric Thomas

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract The inability to control cell proliferation results in the formation of tumors in many multicellular lineages. Nonetheless, little is known about the extent of conservation of the biological traits and ecological factors that promote or inhi

Externí odkaz: https://doaj.org/article/cd26f6fe69714f7291b2d87a33327d20

Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE

Autor: Georges Lacaud, Pierre Savatier, Renaud Mevel, Syed Murtuza Baker, Irene Aksoy, Wen Hao Neo, Rahima Patel, Valerie Kouskoff, Magnus Rattray, Laura Fontenille, Roshana Thambyrajah, Nam Do Khoa, Muhammad Zaki Hidayatullah Fadlullah, Michael Lie-A-Ling

Publikováno v: Fadlullah, M Z H, Neo, W H, Lie-a-ling, M, Thambyrajah, R, Patel, R, Mevel, R, Aksoy, I, Do Khoa, N, Savatier, P, Fontenille, L, Baker, S M, Rattray, M, Kouskoff, V & Lacaud, G 2022, ' Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE ', Blood, vol. 139, no. 3, pp. 343-356 . https://doi.org/10.1182/blood.2020007885, https://doi.org/10.1182/blood.2020007885

In vitro generation and expansion of hematopoietic stem cells (HSCs) holds great promise for the treatment of any ailment that relies on bone marrow or blood transplantation. To achieve this, it is essential to resolve the molecular and cellular path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915a20e90ef52787d2fbf9f575e922b5
https://doi.org/10.1182/blood.2020007885

Flotillin microdomains stabilize cadherins at cell-cell junctions

Autor: Stéphane Bodin, Nam Do Khoa, Emilie Guillaume, Cécile Gauthier-Rouvière, Franck Comunale, Damien Planchon

Publikováno v: Journal of cell science. 126(Pt 22)

Summary Cadherins are essential in many fundamental processes and assemble at regions of cell–cell contact in large macromolecular complexes named adherens junctions. We have identified flotillin 1 and 2 as new partners of the cadherin complexes. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd72fd28abbd63e630aa4f574afabda4
https://pubmed.ncbi.nlm.nih.gov/24046456