Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nam D, Nguyen"'
Autor:
Nam D. Nguyen, Lorena Rosas, Timur Khaliullin, Peiran Jiang, Euxhen Hasanaj, Jose A. Ovando-Ricardez, Marta Bueno, Irfan Rahman, Gloria S. Pryhuber, Dongmei Li, Qin Ma, Toren Finkel, Melanie Königshoff, Oliver Eickelberg, Mauricio Rojas, Ana L. Mora, Jose Lugo-Martinez, Ziv Bar-Joseph
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract The low resolution of spatial transcriptomics data necessitates additional information for optimal use. We developed scDOT, which combines spatial transcriptomics and single cell RNA sequencing to improve the ability to reconstruct single ce
Externí odkaz:
https://doaj.org/article/2220c040f71d4876ae3c2f1dae637a9f
Publikováno v:
BMC Genomics, Vol 20, Iss S12, Pp 1-14 (2019)
Abstract Background The coordination of genomic functions is a critical and complex process across biological systems such as phenotypes or states (e.g., time, disease, organism, environmental perturbation). Understanding how the complexity of genomi
Externí odkaz:
https://doaj.org/article/8df853fa41964498b4a45c3dd4084cc7
Autor:
Nam D Nguyen, Daifeng Wang
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007677 (2020)
The molecular mechanisms and functions in complex biological systems currently remain elusive. Recent high-throughput techniques, such as next-generation sequencing, have generated a wide variety of multiomics datasets that enable the identification
Externí odkaz:
https://doaj.org/article/ed0133b7367d4b22aaab526bf8e5a954
Autor:
Emmanuel Rapp, Zhenyu Lu, Lili Sun, Samantha N. Serna, Marysol Almestica-Roberts, Katherine L. Burrell, Nam D. Nguyen, Cassandra E. Deering-Rice, Christopher A. Reilly
Publikováno v:
Environmental Health Perspectives. 131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23682ddd304e6648a91324e4613c76f5
https://doi.org/10.1289/ehp11076
https://doi.org/10.1289/ehp11076
Autor:
John G. Lamb, Nam D Nguyen, Samantha N. Serna, Marysol Almestica-Roberts, Christopher A. Reilly, Cassandra E. Deering-Rice, Katherine L Burrell, Emmanuel Rapp, Tosifa A. Memon
Publikováno v:
Molecular Pharmacology. 100:295-307
Prior studies revealed increased expression of the transient receptor potential vanilloid-3 (TRPV3) ion channel after wood smoke particulate matter (WSPM) treatment of human bronchial epithelial cells (HBECs). TRPV3 attenuated pathologic endoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787af268f3a30da451d9944a6f21aadb
https://doi.org/10.1124/molpharm.121.000280
https://doi.org/10.1124/molpharm.121.000280
Publikováno v:
Bioinformatics
Summary Population studies such as genome-wide association study have identified a variety of genomic variants associated with human diseases. To further understand potential mechanisms of disease variants, recent statistical methods associate functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb8d9e60c96e2a611542585d98af432
http://europepmc.org/articles/PMC8289382
http://europepmc.org/articles/PMC8289382
Autor:
Cassandra E. Deering-Rice, Nam D Nguyen, Marysol Almestica-Roberts, Katherine L Burrell, Abigail F Scott, Joseph E. Rower, Lili Sun, Tosifa A. Memon, Christopher A. Reilly, Emmanuel Rapp
Publikováno v:
Mol Pharmacol
This study investigated the roles of transient receptor potential (TRP) ankyrin-1 (TRPA1) and TRP vanilloid-3 (TRPV3) in regulating endoplasmic reticulum stress (ERS) and cytotoxicity in human bronchial epithelial cells (HBECs) treated with pneumotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf840ee76e015f7aa154871aff3dd6c3
https://doi.org/10.1124/molpharm.120.000047
https://doi.org/10.1124/molpharm.120.000047
Publikováno v:
Nat Comput Sci
The phenotypes of complex biological systems are fundamentally driven by various multi-scale mechanisms. Multi-modal data, such as single cell multi-omics data, enables a deeper understanding of underlying complex mechanisms across scales for phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6860a16dae7f6c5483dcde42c603c1d0
https://europepmc.org/articles/PMC9038085/
https://europepmc.org/articles/PMC9038085/
Publikováno v:
Photonic Network Communications.
This paper theoretically studies the design and performance analysis of the reliable satellite-based quantum key distribution (QKD) over free-space optics channel. The proposed QKD system is based on the optical quadrature phase-shift keying (QPSK) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daafd23460169596e7fe74a30dc02661
https://doi.org/10.1007/s11107-021-00934-y
https://doi.org/10.1007/s11107-021-00934-y
The biological processes from genotype to phenotype are complex involving multi-scale mechanisms. Increasing multi-modal data enables deeper understanding of underlying complex mechanisms in various phenotypes. However, integrating and interpreting s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa7bbcd0480456387c9f995bd94895b
https://doi.org/10.1101/2021.01.28.428715
https://doi.org/10.1101/2021.01.28.428715