Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nam Ah Kim"'
Autor:
Ravi Maharjan, Junoh Jeong, Ripesh Bhujel, Min-Soo Kim, Hyo-Kyung Han, Nam Ah Kim, Seong Hoon Jeong
Publikováno v:
Molecules, Vol 27, Iss 4, p 1392 (2022)
The solubility of glibenclamide was evaluated in DMSO, NMP, 1,4-dioxane, PEG 400, Transcutol® HP, water, and aqueous mixtures (T = 293.15~323.15 K). It was then recrystallized to solvate and compressed into tablets, of which 30-day stability and dis
Externí odkaz:
https://doaj.org/article/8066851605af43bebbb0513e2ced7e8c
Autor:
Sang-Koo Park, Ga Yeon Noh, Hyun Woo Yu, Eun Chae Lee, Junoh Jeong, Young-Min Park, Hyo-Kyung Han, Seong Hoon Jeong, Nam Ah Kim
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1738 (2021)
The effects of the manufacturing process and the regeneration of Shirasu porous glass (SPG) membranes were investigated on the reproducibility of protein precipitants, termed protein microbeads. Intravenous immunoglobulin (IVIG) was selected as a mod
Externí odkaz:
https://doaj.org/article/6f8696797b444197aef0ecc4a3bca207
Publikováno v:
Molecules, Vol 26, Iss 2, p 390 (2021)
The solubility and dissolution thermodynamics of new c-Met inhibitor, ABN401, were determined in eleven solvents and Transcutol® HP–water mixture (TWM) from 298.15 to 318.15 K. The experimental solubilities were validated using five mathematical m
Externí odkaz:
https://doaj.org/article/ac33d0cf26c5436d9d912ceb0b2ce391
Autor:
Jooseok Kim, Kyung Eui Park, Yoo-Seong Jeong, YeongMun Kim, Hayeon Park, Ji-Hye Nam, Kyungsoo Jung, Woo Sung Son, Hun Soon Jung, Jong-Hwa Lee, Seong Hoon Jeong, Nam Ah Kim, Jae Du Ha, Sung Yun Cho, Yoon-La Choi, Suk-Jae Chung, Jun Young Choi, Sungyoul Hong, Young Kee Shin
Publikováno v:
Cancers, Vol 12, Iss 6, p 1575 (2020)
The receptor tyrosine kinase c-MET regulates processes essential for tissue remodeling and mammalian development. The dysregulation of c-MET signaling plays a role in tumorigenesis. The aberrant activation of c-MET, such as that caused by gene amplif
Externí odkaz:
https://doaj.org/article/a4e636bf703349eda57ca05edb7fda95
Autor:
Nam Ah Kim, Sungyoul Hong, Ki Hyun Kim, Du Hyung Choi, Joo Seok Kim, Kyung Eui Park, Jun Young Choi, Young Kee Shin, Seong Hoon Jeong
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 121 (2020)
c-Met is a receptor tyrosine kinase with no commercially available product despite being a pivotal target in cancer progression. Unlike other c-Met inhibitors that fail clinically, ABN401 is a newly synthesized c-Met inhibitor that is not potentially
Externí odkaz:
https://doaj.org/article/d47a1325e7ed40efa896452cd874650d
Autor:
Dae Gon Lim, Won-Wook Jeong, Nam Ah Kim, Jun Yeul Lim, Seol-Hoon Lee, Woo Sun Shim, Nae-Gyu Kang, Seong Hoon Jeong
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 9, Iss 6, Pp 324-329 (2014)
Glyceryl monooleate (GMO) is a polar lipid that can exist in various liquid crystalline phases in the presence of different amounts of water. It is regarded as a permeation enhancer due to its amphiphilic property. Various phases of GMO/solvent syste
Externí odkaz:
https://doaj.org/article/acde11252bda4de9aa61910426786ef2
Autor:
Kyoung Song, In-Soo Yoon, Nam Ah Kim, Dong-Hwan Kim, Jongmin Lee, Hee Jung Lee, Saehyung Lee, Sunghyun Choi, Min-Koo Choi, Ha Hyung Kim, Seong Hoon Jeong, Woo Sung Son, Dae-Duk Kim, Young Kee Shin
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96967 (2014)
The purpose of this study was to develop a biobetter version of recombinant human interferon-β 1a (rhIFN-β 1a) to improve its biophysical properties, such as aggregation, production and stability, and pharmacokinetic properties without jeopardizing
Externí odkaz:
https://doaj.org/article/df4487c00d654ce3a777458038e8e828
Publikováno v:
Powder Technology. 392:650-660
The present work explores the pharmaceutical application of a novel seeded granulation to develop properties-improved, high drug-loaded, and sustained-release tablets using hydroxypropylcellulose (HPC) as a binder. Itraconazole, 4-acetamidophenol, an
Publikováno v:
Journal of Pharmaceutical Sciences. 110:3188-3199
Low pH virus inactivation (VI) step is routinely used in antibody production manufacturing. In this work, a mimic of the VI step was developed to focus on evaluating adverse effects on product quality. A commercially available lab-scale glass reactor