Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Namık Kılınç"'
1
Identification of Potential Inhibitors for Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) Angiotensin-converting Enzyme 2 and the Main Protease from Anatolian Traditional Plants
Autor: Namık Kılınç, Mikail Açar, Salih Tuncay, Ömer Faruk Karasakal
Publikováno v: Letters in Drug Design & Discovery. 19:996-1006
Background: The 2019 novel coronavirus disease (COVID-19) has caused a global health catastrophe by affecting the human population around the globe. Unfortunately, there is no specific medication or treatment currently available for COVID-19. Objecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1cec716078f3cf15b1cfd542d68d5af
https://doi.org/10.2174/1570180819666211230123145
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2
Resorcinol Derivatives as Novel Aldose Reductase Inhibitors: In Silico and In Vitro Evaluation
Autor: Namık Kılınç
Publikováno v: Letters in Drug Design & Discovery. 19:837-846
Background: The polyol pathway, an alternative way of carbohydrate metabolism, is activated by hyperglycemia. Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, is responsible for the reduction of glucose to sorbitol. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f5be5f74bbb8884f65ea41202d78e15
https://doi.org/10.2174/1570180819666220414103203
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3
Naphthoquinones from Onosma: Molecular Mechanisms of Action in the Treatment and Prevention of COVID-19
Autor: Namık Kılınç
Publikováno v: Volume: 8, Issue: 2 173-184
Caucasian Journal of Science
Absrtact COVID-19, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in December 2019 in Wuhan, China. There is currently no effective treatment or immunization for the virus, and it is spreading rapi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4744628a559e0fc81fadf1d2fe297f29
https://doi.org/10.48138/cjo.1037727
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5
The Evaluation of Inhibition Effects of Antibiotics on the Sheep Stomach Carbonic Anhydrase I and II Isozymes
Autor: Namık Kılınç, Şükrü Beydemir
Publikováno v: Volume: 10, Issue: 3 1811-1819
Journal of the Institute of Science and Technology
Carbonic anhydrases are vital class of enzymes that participate in so many essential physiological events in the organism and associated with many diseases. Inhibitors of carbonic anhydrase enzymes are used in pharmacological applications in many are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc65af6895afca3634f98abd58cea3e9
https://doi.org/10.21597/jist.688416
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6
Synthesis, biological evaluation and molecular docking studies of new 2-ethoxy-4-{[3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl]-azomethine}-phenyl benzenesulfonate derivatives on human aldose reductase enzyme
Autor: Sevda Manap, Namık Kılınç, Haydar Yüksek, Gül Özdemir, Murat Beytur, Muzaffer Alkan
A series of 2-ethoxy-4-{[3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl]-azomethine}-phenyl benzenesulfonates (3) were synthesized from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with 2-ethoxy-4-formyl-phenyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::305d0d0e5f127c5829540ed52e822646
https://doi.org/10.3762/bxiv.2021.31.v1
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7
Synthesis of novel sulfonamides with anti-Alzheimer and antioxidant capacities
Autor: Akın Akıncıoğlu, Süleyman Göksu, Hulya Akincioglu, Namık Kılınç, Edanur Erümit Binici, Nihal Gök
A series of novel dopamine analogs incorporating urea and sulfonamide functional groups was synthesized from 3,4-dimethoxyphenethylamine. The reaction of 3,4-dimethoxyphenethylamine with N,N-dimethylcarbamoyl chloride, followed by the sulfonyl chlori
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5098f7bea988022de903973164fcf1
https://hdl.handle.net/20.500.12501/2628
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9
Effects of glyphosate on juvenile rainbow trout (Oncorhynchus mykiss): Transcriptional and enzymatic analyses of antioxidant defence system, histopathological liver damage and swimming performance
Autor: Orhan Erdoğan, Arzu Uçar, Saltuk Buğrahan Ceyhun, Muhammed Atamanalp, Fatih Akdemir, Ekrem Sulukan, Ahmet Topal, Şükrü Beydemir, Esat Mahmut Kocaman, Namık Kılınç, Ertan Oruç
Publikováno v: Ecotoxicology and Environmental Safety. 111:206-214
This study aims to determine the effect of glyphosate on the transcriptional and enzymatic activity of antioxidant metabolism enzymes of juvenile rainbow trout with short term (6, 12, 24, 48 and 96 h) and long term (21 days) exposures followed by a r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0395efed75f7d0ac4bae52b354b3f70c
https://doi.org/10.1016/j.ecoenv.2014.09.027
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10
İnsan eritrosit karbonik anhidraz izoenzimleri üzerine bazı kardiyovasküler terapötiklerin inhibisyon etkilerinin incelenmesi
Autor: Bülent Şengül, Namık Kılınç, Mehmet Mustafa İşgör, Zuhal Alım, Şükrü Beydemir
Publikováno v: Volume: 7, Issue: 1 90-97
Bitlis Eren Üniversitesi Fen Bilimleri Dergisi
Carbonic anhydrase enzyme plays a vital role in metabolic events such as acid-base regulation and respiration. In our research, it is tried to determine the inhibitory influences of the cardiovascular therapeutics esmolol hydrochloride, amiodarone hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d317a6b5eb22a401bc557b5ab46fd003
https://dergipark.org.tr/tr/pub/bitlisfen/issue/38033/345643
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