Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models

Autor: Diana C. Márquez-Garbán, Cristian D. Yanes, Gabriela Llarena, David Elashoff, Nalo Hamilton, Mary Hardy, Madhuri Wadehra, Susan A. McCloskey, Richard J. Pietras

Publikováno v: Nutrients, Vol 16, Iss 14, p 2369 (2024)

Manuka honey (MH) exhibits potential antitumor activity in preclinical models of a number of human cancers. Treatment in vitro with MH at concentrations ranging from 0.3 to 5.0% (w/v) led to significant dose-dependent inhibition of proliferation of h

Externí odkaz: https://doaj.org/article/ed0fd76d364749de89afce195ef9bc7d

Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC

Autor: Patricia A. Young, MD, Diana C. Márquez-Garbán, MD, Zorawar Singh Noor, MD, Neda Moatamed, MD, David Elashoff, PhD, Tristan Grogan, PhD, Tahmineh Romero, PhD, Hironobu Sasano, MD, PhD, Ryoko Saito, MD, PhD, Rebecca Rausch, PhD, Nalo Hamilton, PhD, Steven M. Dubinett, MD, Edward B. Garon, MD, Richard J. Pietras, MD, PhD

Publikováno v: JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100150- (2021)

Introduction: Estrogen receptors (ER) (ERα, ERβ) and aromatase (key enzyme for estrogen synthesis) are expressed in most human NSCLCs. High intratumoral estrogen levels and elevated aromatase expression in NSCLC predict poor outcome. This open-labe

Externí odkaz: https://doaj.org/article/63c09193397c4c4eb67123c6406d8111

Shift work in nurses: contribution of phenotypes and genotypes to adaptation.

Autor: Karen L Gamble, Alison A Motsinger-Reif, Akiko Hida, Hugo M Borsetti, Stein V Servick, Christopher M Ciarleglio, Sam Robbins, Jennifer Hicks, Krista Carver, Nalo Hamilton, Nancy Wells, Marshall L Summar, Douglas G McMahon, Carl Hirschie Johnson

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18395 (2011)

Daily cycles of sleep/wake, hormones, and physiological processes are often misaligned with behavioral patterns during shift work, leading to an increased risk of developing cardiovascular/metabolic/gastrointestinal disorders, some types of cancer, a

Externí odkaz: https://doaj.org/article/8d500da19fe2447c95043108a448fe1a

Progesterone Receptor Signaling in the Breast Tumor Microenvironment

Autor: Viroj, Boonyaratanakornkit, Eileen M, McGowan, Diana C, Márquez-Garbán, L P, Burton, Nalo, Hamilton, Prangwan, Pateetin, Richard J, Pietras

Publikováno v: Advances in experimental medicine and biology. 1329

The tumor microenvironment (TME) is a complex infrastructure composed of stromal, epithelial, and immune cells embedded in a vasculature ECM. The microenvironment surrounding mammary epithelium plays a critical role during the development and differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::00648ef40f6d4bcac6590eafe88ed82c
https://pubmed.ncbi.nlm.nih.gov/34664251

Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC

Autor: Ryoko Saito, Neda A. Moatamed, Zorawar S. Noor, Patricia A. Young, Richard J. Pietras, Tristan Grogan, Tahmineh Romero, Nalo Hamilton, David Elashoff, Diana C. Márquez-Garbán, Edward B. Garon, Hironobu Sasano, Steven M. Dubinett, Rebecca Rausch

Publikováno v: JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100150-(2021)
JTO Clinical and Research Reports
JTO clinical and research reports, vol 2, iss 4

Introduction Estrogen receptors (ER) (ERα, ERβ) and aromatase (key enzyme for estrogen synthesis) are expressed in most human NSCLCs. High intratumoral estrogen levels and elevated aromatase expression in NSCLC predict poor outcome. This open-label

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b79d45fd194e8c0ee7ce1d865e79032
http://www.sciencedirect.com/science/article/pii/S2666364321000096