Glycan variability on a recombinant IgG antibody transiently produced in HEK-293E cells

Autor: Nallet, Sophie, Fornelli, Luca, Schmitt, Simone, Parra, Julien, Baldi, Lucia, Tsybin, Yury O., Wurm, Florian M.

Publikováno v: In New BIOTECHNOLOGY 15 May 2012 29(4):471-476

Transient Gene Expression in HEK-293E Cells for Recombinant Protein Production:Process Characterization towards GMP Approval

Autor: Nallet, Sophie

The growing demand of biopharmaceutical products is boosting the market for therapeutic recombinant proteins (r-proteins). More than half of the 140 r-proteins that have gained approval for human therapeutic use are manufactured in mammalian cells th

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Quantification of Polyethylenimine in Transient Gene Expression: On the Way to GMP Compliance.

Autor: Nallet, Sophie, Kadlecova, Zuzana, Baldi, Lucia, Klok, Harm-Anton, Wurm, Florian M.

Publikováno v: Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009; 2012, p71-75, 5p

Large-scale ¹³C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli.

Autor: Haverkorn van Rijsewijk, Bart R B, Nanchen, Annik, Nallet, Sophie, Kleijn, Roelco J, Sauer, Uwe

Publikováno v: Molecular Systems Biology; 2011, Vol. 7 Issue 1, p1-N.PAG, 12p, 2 Diagrams, 1 Chart, 6 Graphs