Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Nalini Raghavachari"'
Autor:
Kenneth Walsh, Nalini Raghavachari, Candace Kerr, Alexander G. Bick, Steven R. Cummings, Todd Druley, Cynthia E. Dunbar, Giulio Genovese, Margaret A. Goodell, Siddhartha Jaiswal, Jaroslaw Maciejewski, Pradeep Natarajan, Anastasia V. Shindyapina, Alan R. Shuldiner, Erik B. Van Den Akker, Jan Vijg
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Aging is characterized by increased mortality, functional decline, and exponential increases in the incidence of diseases such as cancer, stroke, cardiovascular disease, neurological disease, respiratory disease, etc. Though the role of aging in thes
Externí odkaz:
https://doaj.org/article/91cc6f1fb0f44f728c443e64a1e07a92
Autor:
Alexander M Kulminski, Amisha V Barochia, Yury Loika, Nalini Raghavachari, Konstantin G Arbeev, Mary K Wojczynski, Bharat Thyagarajan, Badri N Vardarajan, Kaare Christensen, Anatoliy I Yashin, Stewart J Levine
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206873 (2018)
INTRODUCTION:Murine studies have shown that apolipoprotein E modulates pulmonary function during development, aging, and allergen-induced airway disease. It is not known whether the polymorphic human APOE gene influences pulmonary function. OBJECTIVE
Externí odkaz:
https://doaj.org/article/cfb27b87f7b340f2a03582c88aea30c4
Autor:
Tianxiao Huan, Tõnu Esko, Marjolein J Peters, Luke C Pilling, Katharina Schramm, Claudia Schurmann, Brian H Chen, Chunyu Liu, Roby Joehanes, Andrew D Johnson, Chen Yao, Sai-Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G Uitterlinden, Dena G Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger, Marcus Dörr, Stephan B Felix, Tanja Zeller, International Consortium for Blood Pressure GWAS (ICBP), Ramachandran Vasan, Christopher J O'Donnell, Peter J Munson, Xia Yang, Holger Prokisch, Uwe Völker, Joyce B J van Meurs, Luigi Ferrucci, Daniel Levy
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005035 (2015)
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead to BP changes by acting on intermediate molecular phenotypes such as coded protein sequence
Externí odkaz:
https://doaj.org/article/f8560d082fc3446faee8ddcbcfa995fc
Autor:
Shilpa Jain, Maria G Kapetanaki, Nalini Raghavachari, Kimberly Woodhouse, Guoying Yu, Suchitra Barge, Claudia Coronnello, Panayiotis V Benos, Gregory J Kato, Naftali Kaminski, Mark T Gladwin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60932 (2013)
BACKGROUND:Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications. The role for post-transcriptional regulation of the platelet transcriptome by micro
Externí odkaz:
https://doaj.org/article/c4ebd653265b4a60be6e3f1477435a33
Autor:
Valeria Visconte, Nalini Raghavachari, Delong Liu, Keyvan Keyvanfar, Marie J. Desierto, Jichun Chen, Neal S. Young
Publikováno v:
Haematologica, Vol 95, Iss 2 (2010)
Background Somatic mutation in the X-linked phosphatidylinositol glycan class A gene (PIG-A) causes glycosyl phosphatidylinositol anchor deficiency in human patients with paroxysmal nocturnal hemoglobinuria.Design and Methods We produced an animal mo
Externí odkaz:
https://doaj.org/article/4bb77a47a0ba4c2bbde739dd43b62f2d
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6484 (2009)
Global transcriptome analysis of whole blood RNA using microarrays has been proven to be challenging due to the high abundance of globin transcripts that constitute 70% of whole blood mRNA. This is a particular problem in patients with sickle cell di
Externí odkaz:
https://doaj.org/article/d7cb599adce049d3b17b27a6a56f1f5f
Autor:
Adrian Wiestner, Wyndham H. Wilson, Yihong Ye, Kieron Dunleavy, Megan M. Tweito, Therese White, Nalini Raghavachari, Peter J. Munson, Qiuyan Wang, Delong Liu, Patricia Pérez-Galán, Edgar G. Rizzatti, Marc A. Weniger
Purpose: Proteasome inhibition disrupts protein homeostasis and induces apoptosis. Up to 50% of patients with relapsed mantle cell lymphoma (MCL) respond to bortezomib. We used gene expression profiling to investigate the connection between proteasom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39e2af88423ca501ed975864291e05f
https://doi.org/10.1158/1078-0432.c.6519399.v1
https://doi.org/10.1158/1078-0432.c.6519399.v1
Autor:
Adrian Wiestner, Wyndham H. Wilson, Yihong Ye, Kieron Dunleavy, Megan M. Tweito, Therese White, Nalini Raghavachari, Peter J. Munson, Qiuyan Wang, Delong Liu, Patricia Pérez-Galán, Edgar G. Rizzatti, Marc A. Weniger
PDF file - 73K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335e342057e25a6dd1ae13abd4b472a2
https://doi.org/10.1158/1078-0432.22442730.v1
https://doi.org/10.1158/1078-0432.22442730.v1
Publikováno v:
J Gerontol A Biol Sci Med Sci
Background Exceptional longevity as manifested by the lower incidence and delayed onset of age-related disabilities/diseases that include cardiovascular disease, Alzheimer’s disease, cancer is believed to be influenced by inherent protective molecu
Autor:
Nalini Raghavachari
Publikováno v:
J Gerontol A Biol Sci Med Sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1682dede6fefcdd356c957989da884
https://europepmc.org/articles/PMC7750679/
https://europepmc.org/articles/PMC7750679/