Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nalini J. Gupta"'
Autor:
Digumarthi V S Sudhakar, Regur Phanindranath, Shveta Jaishankar, Anand Ramani, Kaustubh P Kalamkar, Umesh Kumar, Asmita D Pawar, Rima Dada, Rajender Singh, Nalini J Gupta, Mamata Deenadayal, Aarti Deenadayal Tolani, Yogendra Sharma, Anuranjan Anand, Jay Gopalakrishnan, Kumarasamy Thangaraj
Publikováno v:
Human Molecular Genetics. 32:533-542
Human spermatogenesis requires an orchestrated expression of numerous genes in various germ cell subtypes. Therefore, the genetic landscape of male infertility is highly complex. Known genetic factors alone account for at least 15% of male infertilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493cd9d4e05529f86160163f96acc6a2
https://doi.org/10.1093/hmg/ddac216
https://doi.org/10.1093/hmg/ddac216
Autor:
Singh Rajender, Kumarasamy Thangaraj, Satya Narayan Sankhwar, Priyamvada Singh, Baidyanath Chakravarty, Nalini J. Gupta, Poonam Mehta
Publikováno v:
J Assist Reprod Genet
PURPOSE: To identify the contribution of mutations in the Desert Hedgehog (DHH) gene to the disorders of sexual differentiation (DSD) and male infertility. METHODS: The study included a total 430 subjects, including 47 gonadal dysgenesis cases, 6 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e22075304bc2c83d615212f96811366
https://doi.org/10.1007/s10815-021-02140-1
https://doi.org/10.1007/s10815-021-02140-1
Autor:
Umesh Kumar, Digumarthi V S Sudhakar, Nithyapriya Kumar, Hanuman T Kale, Rajan Kumar Jha, Nalini J Gupta, B N Chakravarthy, Mamata Deenadayal, Aarti Deenadayal Tolani, Swasti Raychaudhuri, P Chandra Shekar, Kumarasamy Thangaraj
The recent epidemiological studies suggest that nearly one out of every 7 reproductive age couples face problem to conceive a child after trying for at least one year. Impaired fertility of the male partner is causative in approximately 50% of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1234587c45add5609cf6a0ccea7e2caa
https://doi.org/10.1101/2022.01.11.475851
https://doi.org/10.1101/2022.01.11.475851
Novel NR5A1 Pathogenic Variants Cause Phenotypic Heterogeneity in 46,XY Disorders of Sex Development
Autor:
Datar Chaitanya A, Kumarasamy Thangaraj, Rajesh Khadgawat, Jaishree Dhyani, Baidyanath Chakravarthy, Shveta Jaishankar, Mamata Deenadayal, Iram Shabir, Sree Namduri, Nalini J. Gupta, Khadilkar Vaman, Anuranjan Anand, Yogendra Sharma, Digumarthi V. S. Sudhakar, Raghvendra Singh, Umesh Kumar, Usha Kabilan, Phanindranath Regur, Rima Dada
Publikováno v:
Sexual Development. 13:178-186
Steroidogenic factor 1 (NR5A1/SF1) is a key transcription factor that is known to regulate the development of adrenal glands and gonads and is also involved in steroidogenesis. Several pathogenic NR5A1 variants have been reported to cause 46,XY disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a29aea5bc290158c4c27f1ca6a2d31b9
https://doi.org/10.1159/000505527
https://doi.org/10.1159/000505527
Autor:
Gopal Gupta, Singh Rajender, Kumarasamy Thangaraj, Nalini J. Gupta, Satya Narayan Sankhwar, Nishi Gupta, Pravin Kumar Gangwar, Digumarthi V. S. Sudhakar, Baidyanath Chakraborty
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
Prostate specific antigen (PSA/KLK3) is known to be the chief executor of the fragmentation of semenogelins, dissolution of semen coagulum, thereby releasing sperm for active motility. Recent research has found that semenogelins also play significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1c966a5bdf5e5fbdd6fec01995ac02
http://link.springer.com/article/10.1038/s41598-017-10866-1
http://link.springer.com/article/10.1038/s41598-017-10866-1
Novel NR5A1 Pathogenic Variants Cause Phenotypic Heterogeneity in 46,XY Disorders of Sex Development
Autor:
Digumarthi V S, Sudhakar, Shveta, Jaishankar, Phanindranath, Regur, Umesh, Kumar, Raghvendra, Singh, Usha, Kabilan, Sree, Namduri, Jaishree, Dhyani, Nalini J, Gupta, Baidyanath, Chakravarthy, Khadilkar, Vaman, Iram, Shabir, Rajesh, Khadgawat, Mamata, Deenadayal, Datar, Chaitanya A, Rima, Dada, Yogendra, Sharma, Anuranjan, Anand, Kumarasamy, Thangaraj
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 13(4)
Steroidogenic factor 1 (NR5A1/SF1) is a key transcription factor that is known to regulate the development of adrenal glands and gonads and is also involved in steroidogenesis. Several pathogenic NR5A1 variants have been reported to cause 46,XY disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35fbc4ad3de776447589391db20bf5ab
https://pubmed.ncbi.nlm.nih.gov/32008008
https://pubmed.ncbi.nlm.nih.gov/32008008
Autor:
Mamta Deendayal, Singh Rajender, Gyaneshwer Chaubey, Deepa Selvi Rani, Avinash A. Rasalkar, Kumarasamy Thangaraj, Baidyanath Chakravarty, Kadupu Pavani, Nalini J. Gupta
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Deletions in the AZoospermia Factor (AZF) regions (spermatogenesis loci) on the human Y chromosome are reported as one of the most common causes of severe testiculopathy and spermatogenic defects leading to male infertility, yet not much data is avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8dcde0fcf6b722cbfe25ffdaa0293d
https://doi.org/10.1038/s41598-019-42690-0
https://doi.org/10.1038/s41598-019-42690-0
Autor:
Sourav RoyChoudhury, Koel Chaudhury, Sudha Srivastava, Apoorva Singh, Baidyanath Chakravarty, Nalini J. Gupta, Mamata Joshi
Publikováno v:
Human Reproduction. 31:1265-1274
STUDY QUESTION Is there any difference at the serum metabolic level between women with recurrent implantation failure (RIF) and women with recurrent implantation success (RIS) when undergoing in vitro fertilization (IVF)? SUMMARY ANSWER Eight metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99726eb6bb1aff49c30e395406a825ff
https://doi.org/10.1093/humrep/dew064
https://doi.org/10.1093/humrep/dew064
Autor:
Kumarasamy Thangaraj, Sheikh Nizamuddin, J. R. Devi, G. Manisha, M. Deenadayal, Digumarthi V. S. Sudhakar, Baidyanath Chakravarthy, Lalji Singh, Nalini J. Gupta
Publikováno v:
Andrologia. 50(3)
NR5A1 or steroidogenic factor 1 (SF1) is an autosomal gene, which encodes a protein that is a member of nuclear receptor family. NR5A1 regulates the transcription of numerous genes that are expressed in hypothalamic-pituitary-gonadal axis and adrenal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb21a362e1ba8a443fe885ebb4ef4e3
https://pubmed.ncbi.nlm.nih.gov/29265478
https://pubmed.ncbi.nlm.nih.gov/29265478
Autor:
Rajeev Kumar Pandey, Lalji Singh, M. Deenadayal, Digumarthi V. S. Sudhakar, Arun Khattri, Baidyanath Chakravarty, Nalini J. Gupta, Kumarasamy Thangaraj, Venkatesh Pilla Reddy
Publikováno v:
International Journal of Andrology. 35:810-818
Summary Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase, which plays an important role in the spermatogenesis by phosphorylating protamines. It has been shown to be involved in the regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0233c5bb7a2df86f78e731ed928523bc
https://doi.org/10.1111/j.1365-2605.2012.01302.x
https://doi.org/10.1111/j.1365-2605.2012.01302.x