Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Nalini Chandar"'
Autor:
Elisha Pendleton, Anthony Ketner, Phil Ransick, Doug Ardekani, Thomas Bodenstine, Nalini Chandar
Publikováno v:
Biology, Vol 13, Iss 1, p 39 (2024)
Loss of function of the Retinoblastoma gene (RB1) due to mutations is commonly seen in human osteosarcomas. One of the Rb1 gene functions is to facilitate cell fate from mesenchymal stem cells to osteoblasts and prevent adipocyte differentiations. In
Externí odkaz:
https://doaj.org/article/846d3af2325840699c40edcb0bcbc3fc
Autor:
Shivang Shah, Elisha Pendleton, Oliver Couture, Mustafa Broachwalla, Teresa Kusper, Lauren A.C. Alt, J. Fay Michael, Nalini Chandar
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100920- (2021)
In order to understand the role of the p53 tumor suppressor gene in microRNA expression during osteoblast differentiation, we used a screen to identify microRNAs that were altered in a p53-dependent manner. MicroRNAs from MC3T3-E1 preosteoblasts were
Externí odkaz:
https://doaj.org/article/894c5e145c6b4777855f9a79d4eed578
Autor:
Elisha Pendleton, Nalini Chandar
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Osteoblasts and adipocytes originate from common mesenchymal progenitor cells and are controlled by specific transcription factors. While 1,25-dihydroxyvitamin D3 (vitamin D) is known to be an important factor for osteoblast differentiation, there ar
Externí odkaz:
https://doaj.org/article/2bf85c239a444dc784c3f4c81650f460
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82494 (2013)
The tumor suppressor gene p53 is involved in a variety of cellular activities such as cellular stress responses, cell cycle regulation and differentiation. In our previous studies we have shown p53's transcription activating role to be important in o
Externí odkaz:
https://doaj.org/article/12cf636a00294535821e2f1e17c5e348
Autor:
Sandhya Noronha, Brian Zanotti, Nalini Chandar, Taylor E Scimeca, Shubha Mathur, Michael J. Fay, Justyna Obrzut, Omran Zarou, Joseph Rojas, Ribhi Salamah, Elizabeth A Hayward, Akhil Pillai, Lauren A.C. Alt
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 54:71-84
Liposarcoma is a malignant soft tissue tumor that originates from adipose tissue and is one of the most frequently diagnosed soft tissue sarcomas in humans. There is great interest in identifying novel chemotherapeutic options for treating liposarcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63af8f8cbb785e32fb9be249081f6c9b
https://doi.org/10.1007/s11626-017-0208-4
https://doi.org/10.1007/s11626-017-0208-4
Publikováno v:
Cancer Research. 80:2476-2476
Retinoblastoma gene (Rb1) loss of function mutations is commonly seen in osteosarcomas resulting in poorly differentiated tumors. In addition to cell cycle regulation, Rb1 function has been shown to be important in cell fate determination. It is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e34fb48d54f3d4e7e91a7370119ccaf2
https://doi.org/10.1158/1538-7445.am2020-2476
https://doi.org/10.1158/1538-7445.am2020-2476
Autor:
Nalini Chandar, Elisha Pendleton
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Frontiers in Endocrinology
Frontiers in Endocrinology
Osteoblasts and adipocytes originate from common mesenchymal progenitor cells and are controlled by specific transcription factors. While 1,25-dihydroxyvitamin D3 (vitamin D) is known to be an important factor for osteoblast differentiation, there ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef7c266909519a942d07a020b1e6e28
http://journal.frontiersin.org/article/10.3389/fendo.2017.00128/full
http://journal.frontiersin.org/article/10.3389/fendo.2017.00128/full
Autor:
Lon J. Van Winkle, Paulette Burdick, Bryan C. Bjork, Nalini Chandar, Jacalyn M. Green, Sean M. Lynch, Sophie La Salle, Susan M. Viselli, Chester Robson
Publikováno v:
Medical Science Educator. 24:279-290
Meta-analyses of findings for nonmedical curricula show that course-based community service, such as service learning, improves students’ academic achievement and their personal, social, and citizenship outcomes. Based on this strong evidence for K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44580e177a02a1182e858bbc9fc73936
https://doi.org/10.1007/s40670-014-0049-7
https://doi.org/10.1007/s40670-014-0049-7
Autor:
Elisha Pendleton, Shivang Shah, Oliver Couture, Teresa Kusper, Mustafa Broachwalla, Lauren Alt, Michael Fay, Nalini Chandar
Publikováno v:
Cancer Research. 79:1796-1796
We have previously shown a role for tumor suppressor gene p53 in the transcriptional activation of several bone-specific genes in osteoblast differentiation. In this study, we used a screen for microRNAs to look for ones that were p53 dependent and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a91b361bfd37ca58ae1f4e7121f32a0d
https://doi.org/10.1158/1538-7445.am2019-1796
https://doi.org/10.1158/1538-7445.am2019-1796
Autor:
Lon J. Van Winkle, Sophie La Salle, Lendell Richardson, Bryan C. Bjork, Paulette Burdick, Nalini Chandar, Jacalyn M. Green, Sean M. Lynch, Chester Robson, Susan M. Viselli
Publikováno v:
Medical Science Educator. 23:217-224
We used three approaches to determine whether first-year medical students would begin to confront their biases in response to a simulated encounter with an incarcerated, African-American patient. The patient presented with fatigue in a Biochemistry c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c0ff984ebe419a7a8ffc87b81fc0d2e
https://doi.org/10.1007/bf03341624
https://doi.org/10.1007/bf03341624