Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models

Autor: Furth, Priscilla A., Cabrera, M. Carla, Díaz-Cruz, Edgar S., Millman, Sarah, Nakles, Rebecca E.

Aberrations in estrogen signaling increase breast cancer risk. Molecular mechanisms that impact breast cancer initiation, promotion, and progression can be investigated using genetically engineered mouse models. Increasing estrogen receptor alpha (ER

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23829562cd4315ae834cc9f2cdb3678e
https://europepmc.org/articles/PMC3154027/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The PPARγ Agonist Efatutazone Increases the Spectrum of Well-Differentiated Mammary Cancer Subtypes Initiated by Loss of Full-Length BRCA1in Association with TP53Haploinsufficiency

Autor: Nakles, Rebecca E., Kallakury, Bhaskar V.S., Furth, Priscilla A.

Publikováno v: American Journal of Pathology; June 2013, Vol. 182 Issue: 6 p1976-1985, 10p

Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice.

Autor: Miermont AM; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Cabrera MC; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Frech SM; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Nakles RE; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Diaz-Cruz ES; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Shiffert MT; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA ; Department of Biology, Georgetown University, Washington, DC, 20007, USA., Furth PA; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA ; Department of Medicine, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA ; Department of Nanobiomedical Science and WCU Research Center of Nanobiomedical Science, Dankook University, Chungnam 330-714, Korea.

Publikováno v: Anatomy & physiology : current research [Anat Physiol] 2012 Jun 25; Vol. Suppl 12.