Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Nakauka-Ddamba A"'
Autor:
Maryam Yousefi, Angela Nakauka-Ddamba, Corbett T. Berry, Ning Li, Jenna Schoenberger, Kamen P. Simeonov, Ryan J. Cedeno, Zhengquan Yu, Christopher J. Lengner
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 703-711 (2018)
Summary: Aging is a complex process associated with a decline in functionality of adult stem cells affecting tissue homeostasis and regeneration. Calorie restriction (CR) is the only experimental manipulation known to extend lifespan and reduce the i
Externí odkaz:
https://doaj.org/article/fae24ad16cae4f098e0b844d45d9bd30
Autor:
Benjamin Cieply, Juw Won Park, Angela Nakauka-Ddamba, Thomas W. Bebee, Yang Guo, Xuequn Shang, Christopher J. Lengner, Yi Xing, Russ P. Carstens
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 247-255 (2016)
Alternative splicing (AS) plays a critical role in cell fate transitions, development, and disease. Recent studies have shown that AS also influences pluripotency and somatic cell reprogramming. We profiled transcriptome-wide AS changes that occur du
Externí odkaz:
https://doaj.org/article/2ec97117acb34c46b3cda82737fdcc0b
Autor:
Ning Li, Maryam Yousefi, Angela Nakauka-Ddamba, Fan Li, Lee Vandivier, Kimberly Parada, Dong-Hun Woo, Shan Wang, Ammar S. Naqvi, Shilpa Rao, John Tobias, Ryan J. Cedeno, Gerard Minuesa, Katz Y, Trevor S. Barlowe, Alexander Valvezan, Sheila Shankar, Raquel P. Deering, Peter S. Klein, Shane T. Jensen, Michael G. Kharas, Brian D. Gregory, Zhengquan Yu, Christopher J. Lengner
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2440-2455 (2015)
Members of the Msi family of RNA-binding proteins have recently emerged as potent oncoproteins in a range of malignancies. MSI2 is highly expressed in hematopoietic cancers, where it is required for disease maintenance. In contrast to the hematopoiet
Externí odkaz:
https://doaj.org/article/48f8b5528eca4e5fa6bb5060ea98df07
Autor:
Ryan James Cedeno, Angela Nakauka-Ddamba, Maryam Yousefi, Stephanie Sterling, Nicolae Adrian Leu, Ning Li, John R Pehrson, Christopher Joachim Lengner
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185196 (2017)
A stem cell's epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown
Externí odkaz:
https://doaj.org/article/ca70c7c3afb647479940f645146dc903
Autor:
Ning Li, Maryam Yousefi, Angela Nakauka-Ddamba, Rajan Jain, John Tobias, Jonathan A. Epstein, Shane T. Jensen, Christopher J. Lengner
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 876-891 (2014)
The recent development of targeted murine reporter alleles as proxies for intestinal stem cell activity has led to significant advances in our understanding of somatic stem cell hierarchies and dynamics. Analysis of these reporters has led to a model
Externí odkaz:
https://doaj.org/article/68c8eda97f71447d8c38ed45f9e71d29
Autor:
Cedeno, Ryan James1,2, Nakauka-Ddamba, Angela1, Yousefi, Maryam1,2, Sterling, Stephanie1,3, Leu, Nicolae Adrian1,3, Li, Ning1, Pehrson, John R.1, Lengner, Christopher Joachim1,3,4,5 lengner@vet.upenn.edu
Publikováno v:
PLoS ONE. 9/21/2017, Vol. 12 Issue 9, p1-20. 20p.
Autor:
Yousefi, Maryam, Nakauka-Ddamba, Angela, Berry, Corbett T., Li, Ning, Schoenberger, Jenna, Bankler-Jukes, Devon, Simeonov, Kamen P., Cedeno, Ryan J., Yu, Zhengquan, Lengner, Christopher J.
Publikováno v:
In Stem Cell Reports 11 April 2023 18(4):1048-1048
Autor:
Shane T. Jensen, Edward E. Morrisey, Christopher J. Lengner, Maryam Yousefi, Ning Li, John W. Tobias, Angela Nakauka-Ddamba
Publikováno v:
Developmental Dynamics. 245:822-833
Background Canonical Wnt pathway signaling is necessary for maintaining the proliferative capacity of mammalian intestinal crypt base columnar stem cells (CBCs). Furthermore, dysregulation of the Wnt pathway is a major contributor to disease, includi
Autor:
Ning Li, Christopher J. Lengner, Jenna Schoenberger, Shan Wang, Shane T. Jensen, Zhengquan Yu, Maryam Yousefi, Kimberly Davidow, Angela Nakauka-Ddamba, Michael G. Kharas
Publikováno v:
The Journal of Cell Biology
This work demonstrates that Msi RNA-binding proteins are required for the exit of reserve intestinal stem cells from quiescence and further illustrates the importance of maintaining a quiescent pool of stem cells for regeneration of the intestinal ep
Autor:
Angela Nakauka-Ddamba, Kimberly Parada, Raquel P. Deering, John W. Tobias, Brian D. Gregory, Shan Wang, Ning Li, Gerard Minuesa, Shilpa Rao, Fan Li, Trevor S. Barlowe, Lee E. Vandivier, Michael G. Kharas, Maryam Yousefi, Ryan J. Cedeno, Yarden Katz, Dong Hun Woo, Shane T. Jensen, Sheila Shankar, Alexander J. Valvezan, Ammar S. Naqvi, Christopher J. Lengner, Peter S. Klein, Zhengquan Yu
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2440-2455 (2015)
SummaryMembers of the Msi family of RNA-binding proteins have recently emerged as potent oncoproteins in a range of malignancies. MSI2 is highly expressed in hematopoietic cancers, where it is required for disease maintenance. In contrast to the hema