A Conserved Glycan in the C2 Domain of HIV-1 Envelope Acts as a Molecular Switch to Control X4 Utilization by Clonal Variants with Identical V3 Loops.

Autor: Lombardi, Francesca¹, Nakamura, Kyle J.¹, Chen, Thomas¹, Sobrera, Edwin R.¹, Tobin, Nicole H.¹, Aldrovandi, Grace M.¹ GAldrovandi@chla.usc.edu

Publikováno v: PLoS ONE. Jun2015, Vol. 10 Issue 6, p1-16. 16p.

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Unique genotypic features of HIV-1 C gp41 membrane proximal external region variants during pregnancy relate to mother-to-child transmission via breastfeeding.

Autor: Yin L; Molecular HIV Host Interaction Section, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA., Chang KF; Molecular HIV Host Interaction Section, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA., Nakamura KJ; Illumina Inc., San Diego, CA, USA., Kuhn L; Gertrude H. Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Aldrovandi GM; Department of Pediatrics, Sabin Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA., Goodenow MM; Molecular HIV Host Interaction Section, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.

Publikováno v: Journal of clinical pediatrics and neonatology [J Clin Pediatr Neonatol] 2021; Vol. 1 (1), pp. 9-20.