How the initiating ribosome copes with ppGpp to translate mRNAs

Autor: Vinogradova, Daria S., Zegarra, Victor, Maksimova, Elena, Nakamoto, Jose Alberto, Kasatsky, Pavel, Paleskava, Alena, Konevega, Andrey L., Milón, Pohl

Publikováno v: Universidad Peruana de Ciencias Aplicadas (UPC)Repositorio Academico - UPCPLoS Biology.

During host colonization, bacteria use the alarmones (p)ppGpp to reshape their proteome by acting pleiotropically on DNA, RNA, and protein synthesis. Here, we elucidate how the initiating ribosome senses the cellular pool of guanosine nucleotides and

Externí odkaz: http://hdl.handle.net/10757/652189

How the initiating ribosome copes with ppGpp to translate mRNAs.

Autor: Vinogradova DS; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC 'Kurchatov Institute', Gatchina, Russia.; NanoTemper Technologies Rus, Saint Petersburg, Russia., Zegarra V; Centre for Research and Innovation, Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru., Maksimova E; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC 'Kurchatov Institute', Gatchina, Russia., Nakamoto JA; Centre for Research and Innovation, Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru., Kasatsky P; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC 'Kurchatov Institute', Gatchina, Russia., Paleskava A; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC 'Kurchatov Institute', Gatchina, Russia.; Peter the Great Saint Petersburg Polytechnic University, Saint Petersburg, Russia., Konevega AL; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC 'Kurchatov Institute', Gatchina, Russia.; Peter the Great Saint Petersburg Polytechnic University, Saint Petersburg, Russia.; NRC 'Kurchatov Institute,' Moscow, Russia., Milón P; Centre for Research and Innovation, Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru.

Publikováno v: PLoS biology [PLoS Biol] 2020 Jan 29; Vol. 18 (1), pp. e3000593. Date of Electronic Publication: 2020 Jan 29 (Print Publication: 2020).