Zobrazeno 1 - 10 of 646 pro vyhledávání: '"Nakagome I"'
1
Akademický článek
Design and Pharmacological Chaperone Effects of N -(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.
Autor: Kato A; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Nakagome I; School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Kise M; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Yoshimura K; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Tanaka N; School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Nash RJ; Institute of Biological, Environmental and Rural Sciences / Phytoquest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, U.K., Fleet GWJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, U.K., Kobayashi Y; Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama 930-8555, Japan., Ikeda H; Faculty of Engineering, University of Toyama, Toyama 930-8555, Japan., Okada T; Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama 930-8555, Japan.; Faculty of Engineering, University of Toyama, Toyama 930-8555, Japan., Toyooka N; Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama 930-8555, Japan.; Faculty of Engineering, University of Toyama, Toyama 930-8555, Japan.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Jul 13; Vol. 66 (13), pp. 9023-9039. Date of Electronic Publication: 2023 Jun 14.
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2
Akademický článek
Introduction of C -alkyl branches to L-iminosugars changes their active site binding orientation.
Autor: Kato A; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp., Nakagome I; School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan., Yoshimura K; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp., Kanekiyo U; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp., Kishida M; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp., Shinzawa K; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp., Lu TT; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. yucy@iccas.ac.cn.; University of Chinese Academy of Sciences, Beijing 100049, China., Li YX; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. yucy@iccas.ac.cn.; University of Chinese Academy of Sciences, Beijing 100049, China., Nash RJ; Institute of Biological, Environmental and Rural Sciences/Phytoquest Limited, Plas Gogerddan, Aberystwyth, Ceredigion, SY23 3EB, UK., Fleet GWJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, OX1 3TA, UK., Tanaka N; School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan., Yu CY; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. yucy@iccas.ac.cn.; University of Chinese Academy of Sciences, Beijing 100049, China.
Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2022 Sep 21; Vol. 20 (36), pp. 7250-7260. Date of Electronic Publication: 2022 Sep 21.
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3
Akademický článek
5- C -Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Autor: Kato A; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Nakagome I; School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Kanekiyo U; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Lu TT; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Li YX; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Yoshimura K; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Kishida M; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Shinzawa K; Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan., Yoshida T; School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Tanaka N; School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Jia YM; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Nash RJ; Institute of Biological, Environmental and Rural Sciences / Phytoquest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, U.K., Fleet GWJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, U.K., Yu CY; Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Feb 10; Vol. 65 (3), pp. 2329-2341. Date of Electronic Publication: 2022 Jan 24.
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4
Conference
Analysis of the kinetic energy from fission fragments using dynamical model.
Autor: Takagi, S.1,2 shinya_takagi@kindai.ac.jp, Aritomo, Y.1, Hirose, K.2, Nishio, K.2
Publikováno v: EPJ Web of Conferences. 10/18/2024, Vol. 306, p1-5. 5p.
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5
Akademický článek
Colchicine, Caffeine, Gramine, and Their Derivatives as Potential Herbicides, Fungicides, and Insecticides.
Autor: Kurek, Joanna1 (AUTHOR) joankur@amu.edu.pl, Sierakowska, Arleta1 (AUTHOR), Berdzik, Natalia1 (AUTHOR), Jasiewicz, Beata1 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10081. 18p.
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6
Akademický článek
Effect of isavuconazole on the pharmacokinetics of sunitinib and its mechanism.
Autor: Hu, Jinyu1 (AUTHOR), Xia, Hailun1 (AUTHOR), Chen, Xiaohai1 (AUTHOR), Xu, Xinhao1 (AUTHOR), Wu, Hua-Lu1 (AUTHOR), Shen, Yuxin1 (AUTHOR), Xu, Ren-ai1 (AUTHOR) xra@wmu.edu.cn, Wu, Wenzhi1 (AUTHOR) wwzljy@163.com
Publikováno v: BMC Cancer. 9/11/2024, Vol. 24 Issue 1, p1-11. 11p.
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7
Akademický článek
Drug Repurposing Approach to Identify Candidate Drug Molecules for Hepatocellular Carcinoma.
Autor: Baser, Tugce1 (AUTHOR) e148008@metu.edu.tr, Rifaioglu, Ahmet Sureyya2,3 (AUTHOR), Atalay, Mehmet Volkan4 (AUTHOR), Atalay, Rengul Cetin1 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9392. 20p.
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8
Akademický článek
Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity.
Autor: Kato A; Department of Hospital Pharmacy, University of Toyama, Toyama 930-0194, Japan., Nakagome I; School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan., Hata M; Department of Hospital Pharmacy, University of Toyama, Toyama 930-0194, Japan., Nash RJ; Institute of Biological, Environmental and Rural Sciences, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK., Fleet GWJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Natori Y; Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Sendai 981-8558, Japan., Yoshimura Y; Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Sendai 981-8558, Japan., Adachi I; Department of Hospital Pharmacy, University of Toyama, Toyama 930-0194, Japan., Hirono S; School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.
Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 19; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 19.
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10
Akademický článek
Physicochemical modelling of the retention mechanism of temperature-responsive polymeric columns for HPLC through machine learning algorithms.
Autor: Bandini, Elena1 (AUTHOR) elena.bandini@ugent.be, Castellano Ontiveros, Rodrigo2 (AUTHOR), Kajtazi, Ardiana1 (AUTHOR), Eghbali, Hamed3 (AUTHOR), Lynen, Frédéric1 (AUTHOR)
Publikováno v: Journal of Cheminformatics. 6/21/2024, Vol. 16 Issue 1, p1-12. 12p.
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