Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Nak-Kyun Soung"'
Autor:
Nak-Kyun Soung, Hye-Min Kim, Yukihiro Asami, Dong Hyun Kim, Yangrae Cho, Ravi Naik, Yerin Jang, Kusic Jang, Ho Jin Han, Srinivas Rao Ganipisetti, Hyunjoo Cha-Molstad, Joonsung Hwang, Kyung Ho Lee, Sung-Kyun Ko, Jae-Hyuk Jang, In-Ja Ryoo, Yong Tae Kwon, Kyung Sang Lee, Hiroyuki Osada, Kyeong Lee, Bo Yeon Kim, Jong Seog Ahn
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-14 (2019)
Cancer: How a plant metabolite analog suppresses tumor growth A synthetic analog of a chemical found in fruit suppresses tumor growth by targeting an RNA-binding protein (hnRNPA2B1) and preventing the production of a pro-cancer regulatory factor. Nak
Externí odkaz:
https://doaj.org/article/590b138997084a14a74110e5433070ff
Autor:
Mi-Lang Kyun, Sun-Ok Kim, Hee Gu Lee, Jeong-Ah Hwang, Joonsung Hwang, Nak-Kyun Soung, Hyunjoo Cha-Molstad, Sangku Lee, Yong Tae Kwon, Bo Yeon Kim, Kyung Ho Lee
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1447-1462.e5 (2020)
Summary: Primary cilium is an antenna-like microtubule-based cellular sensing structure. Abnormal regulation of the dynamic assembly and disassembly cycle of primary cilia is closely related to ciliopathy and cancer. The Wnt signaling pathway plays a
Externí odkaz:
https://doaj.org/article/23cb1a5d561a4ae391a1c6f860d1d694
Autor:
Pethaiah Gunasekaran, Ho Jin Han, Jung hoon Choi, Eun Kyoung Ryu, Nam Yeong Park, Geul Bang, Yeo Kyung La, Sunghyun Park, Kyubin Hwang, Hak Nam Kim, Mi-Hyun Kim, Young Ho Jeon, Nak-Kyun Soung, Jeong Kyu Bang
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2071 (2021)
Cancer has been identified as a leading cause of death worldwide, and the increasing number of cancer cases threatens to shorten the average life expectancy of people. Recently, we reported a 3-azido-3-deoxythymidine (AZT)-based amphipathic small mol
Externí odkaz:
https://doaj.org/article/2de5bc07da99411585d0a8a95c7d4fc3
Publikováno v:
Molecules, Vol 26, Iss 20, p 6100 (2021)
Bisphenol A (BPA) is a typical environmental endocrine disruptor that exhibits estrogen-mimicking, hormone-like properties and can cause the collapse of bone homeostasis by an imbalance between osteoblasts and osteoclasts. Various BPA substitutes, st
Externí odkaz:
https://doaj.org/article/7baa6260f3e44c42940c925eea708b94
Autor:
Ho Jin Han, Chanmi Park, Joonsung Hwang, Thimmegowda N.R., Sun-Ok Kim, Junyeol Han, Minsik Woo, Shwetha B, In-Ja Ryoo, Kyung Ho Lee, Hyunjoo Cha-Molstad, Yong Tae Kwon, Bo Yeon Kim, Nak-Kyun Soung
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4800 (2020)
In the past, several microtubule targeting agents (MTAs) have been developed into successful anticancer drugs. However, the usage of these drugs has been limited by the acquisition of drug resistance in many cancers. Therefore, there is a constant de
Externí odkaz:
https://doaj.org/article/ffb2d3689c4a42e3b75230965ab5548b
Autor:
Hwa-Young Lee, Soo-Hyun Park, Soo-Wan Chae, Nak-Kyun Soung, Mi-Jin Oh, Jin Sung Kim, Young Ock Kim, Han-Jung Chae
Publikováno v:
Journal of Functional Foods, Vol 13, Iss , Pp 192-203 (2015)
Ginseng, a medicinal herb, has a large number of active ingredients including steroidal saponins, commonly known as ginsenosides, which have biological functions including anti-osteoporotic effects. In this study, six ginsenosides were identified in
Externí odkaz:
https://doaj.org/article/d359b91b06354c6fb4e82e87f3de0c03
Autor:
Jun-Pil Jang, Hye Jin Jung, Jang Mi Han, Narae Jung, Yonghyo Kim, Ho Jeong Kwon, Sung-Kyun Ko, Nak-Kyun Soung, Jae-Hyuk Jang, Jong Seog Ahn
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184339 (2017)
In the course of searching for angiogenesis inhibitors from microorganisms, two cyclic peptides, PF1171A (1) and PF1171C (2) were isolated from the soil fungus Penicillium sp. FN070315. In the present study, we investigated the antiangiogenic efficac
Externí odkaz:
https://doaj.org/article/55d501d32b1a4413acaf5da062107b19
Autor:
Yangrae Cho, Mina Jang, Akhil Srivastava, Jae-Hyuk Jang, Nak-Kyun Soung, Sung-Kyun Ko, Dae-Ook Kang, Jong Seog Ahn, Bo Yeon Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127140 (2015)
Alternaria brassicicola causes black spot disease of Brassica species. The functional importance of pectin digestion enzymes and unidentified phytotoxins in fungal pathogenesis has been suspected but not verified in A. brassicicola. The fungal transc
Externí odkaz:
https://doaj.org/article/e567611d304d4c20b75ad8f6b367095f
Autor:
Hye-Min Kim, Dong Hyun Kim, Ho-Jin Han, Chan-Mi Park, Srinivas Rao Ganipisetti, Mariadhas Valan Arasu, Young Ock Kim, Chun Geun Park, Bo-Yeon Kim, Nak-Kyun Soung
Publikováno v:
Molecules, Vol 22, Iss 1, p 42 (2016)
Bone homeostasis is tightly regulated to balance bone formation and bone resorption. Many anabolic drugs are used as bone-targeted therapeutic agents for the promotion of osteoblast-mediated bone formation or inhibition of osteoclast-mediated bone re
Externí odkaz:
https://doaj.org/article/ca3701c400dd4346b84eb9cdaba9eb78
Autor:
Ho-Chul Shin, Cheolju Lee, Seung Jun Kim, Geul Bang, Jin Young Kim, Nak-Kyun Soung, Jihyo Kim, Joonsung Hwang, Kyung Ho Lee, Jung Gi Kim, Jeong Kyu Bang, Shinyeong Ju, Taewook Seo, Hye Seon Lee, Laxman Nawale, Bo Yeon Kim, Hyunjoo Cha-Molstad, Goeun Han
Publikováno v:
Cellular and Molecular Life Sciences
Protein arginylation is a critical regulator of a variety of biological processes. The ability to uncover the global arginylation pattern and its associated signaling pathways would enable us to identify novel disease targets. Here, we report the dev