Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Nak Kyun Soung"'
Autor:
Krisada Sakchaisri, Sun-Ok Kim, Joonsung Hwang, Nak Kyun Soung, Kyung Ho Lee, Tae Woong Choi, Yongjun Lee, Chan-Mi Park, Naraganahalli R Thimmegowda, Phil Young Lee, Bettaswamigowda Shwetha, Ganipisetti Srinivasrao, Thi Thu Huong Pham, Jae-Hyuk Jang, Hye-Won Yum, Young-Joon Surh, Kyung S Lee, Hwangseo Park, Seung Jun Kim, Yong Tae Kwon, Jong Seog Ahn, Bo Yeon Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173311 (2017)
We have identified the small molecule STK899704 as a structurally novel tubulin inhibitor. STK899704 suppressed the proliferation of cancer cell lines from various origins with IC50 values ranging from 0.2 to 1.0 μM. STK899704 prevented the polymeri
Externí odkaz:
https://doaj.org/article/53c5ed3bb2c74f4b8592b3078263b538
Autor:
Sun-Ok Kim, Krisada Sakchaisri, N. R. Thimmegowda, Nak Kyun Soung, Jae-Hyuk Jang, Young Sang Kim, Kyung Sang Lee, Yong Tae Kwon, Yukihiro Asami, Jong Seog Ahn, Raymond Leo Erikson, Bo Yeon Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/52ebc51610de49e49609bfd3589294fb
Autor:
Sun-Ok Kim, Krisada Sakchaisri, N R Thimmegowda, Nak Kyun Soung, Jae-Hyuk Jang, Young Sang Kim, Kyung Sang Lee, Yong Tae Kwon, Yukihiro Asami, Jong Seog Ahn, Raymond Leo Erikson, Bo Yeon Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53908 (2013)
STK295900, a small synthetic molecule belonging to a class of symmetric bibenzimidazoles, exhibits antiproliferative activity against various human cancer cell lines from different origins. Examining the effect of STK295900 in HeLa cells indicates th
Externí odkaz:
https://doaj.org/article/63f6f3a1e25b4d7c94e5ff019b4c0274
Autor:
Pethaiah Gunasekaran, Ho Jin Han, Jung hoon Choi, Eun Kyoung Ryu, Nam Yeong Park, Geul Bang, Yeo Kyung La, Sunghyun Park, Kyubin Hwang, Hak Nam Kim, Mi-Hyun Kim, Young Ho Jeon, Nak-Kyun Soung, Jeong Kyu Bang
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2071 (2021)
Cancer has been identified as a leading cause of death worldwide, and the increasing number of cancer cases threatens to shorten the average life expectancy of people. Recently, we reported a 3-azido-3-deoxythymidine (AZT)-based amphipathic small mol
Externí odkaz:
https://doaj.org/article/2de5bc07da99411585d0a8a95c7d4fc3
Autor:
Jun-Pil Jang, Hye Jin Jung, Jang Mi Han, Narae Jung, Yonghyo Kim, Ho Jeong Kwon, Sung-Kyun Ko, Nak-Kyun Soung, Jae-Hyuk Jang, Jong Seog Ahn
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184339 (2017)
In the course of searching for angiogenesis inhibitors from microorganisms, two cyclic peptides, PF1171A (1) and PF1171C (2) were isolated from the soil fungus Penicillium sp. FN070315. In the present study, we investigated the antiangiogenic efficac
Externí odkaz:
https://doaj.org/article/55d501d32b1a4413acaf5da062107b19
Autor:
Ho-Chul Shin, Cheolju Lee, Seung Jun Kim, Geul Bang, Jin Young Kim, Nak-Kyun Soung, Jihyo Kim, Joonsung Hwang, Kyung Ho Lee, Jung Gi Kim, Jeong Kyu Bang, Shinyeong Ju, Taewook Seo, Hye Seon Lee, Laxman Nawale, Bo Yeon Kim, Hyunjoo Cha-Molstad, Goeun Han
Publikováno v:
Cellular and Molecular Life Sciences
Protein arginylation is a critical regulator of a variety of biological processes. The ability to uncover the global arginylation pattern and its associated signaling pathways would enable us to identify novel disease targets. Here, we report the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d201d5ec7114c79111e0e4d9a30631
https://doi.org/10.1007/s00018-021-03805-x
https://doi.org/10.1007/s00018-021-03805-x
Autor:
Young-Ho Chung, Nak-Kyun Soung, Minkyoung Kim, Joonhyeok Choi, Young-Ho Lee, Kyeong-Ryoon Lee, Eunice EunKyeong Kim, Min Ju Kim, Young-Ho Jeon, Kyeong Lee, Mija Ahn, Eun Kyoung Ryu, Kyung S. Lee, Geul Bang, Pethaiah Gunasekaran, Jung-Eun Park, Min Su Yim, Jaehi Kim, Sang Chul Shin, Bo Yeon Kim, Jeong Kyu Bang, Hak Nam Kim
Publikováno v:
J Med Chem
Polo-like kinase-1 (Plk1) plays a key role in mitosis and has been identified as an attractive anticancer drug target. Plk1 consists of two drug-targeting sites, namely, N-terminal kinase domain (KD) and C-terminal polo-box domain (PBD). As KD-target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09ba030bf0ccfa229b3bbdeb4c2c5b8
https://doi.org/10.1021/acs.jmedchem.0c01451
https://doi.org/10.1021/acs.jmedchem.0c01451
Publikováno v:
Molecules
Volume 26
Issue 20
Molecules, Vol 26, Iss 6100, p 6100 (2021)
Volume 26
Issue 20
Molecules, Vol 26, Iss 6100, p 6100 (2021)
Bisphenol A (BPA) is a typical environmental endocrine disruptor that exhibits estrogen-mimicking, hormone-like properties and can cause the collapse of bone homeostasis by an imbalance between osteoblasts and osteoclasts. Various BPA substitutes, st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9952d95e00bab5c74e50dc99215a24
Autor:
Jin Tae Hong, Ji Eun Yu, Kyung Ho Lee, Sun-Ok Kim, Bo Yeon Kim, Nak-Kyun Soung, Joonsung Hwang, Hyunjoo Cha-Molstad, Yong Tae Kwon, Jeong-Ah Hwang
Publikováno v:
EMBO Reports
β‐Catenin is a multifunctional protein and participates in numerous processes required for embryonic development, cell proliferation, and homeostasis through various molecular interactions and signaling pathways. To date, however, there is no dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6690da7a42a712550e1f61afd6f030
https://doi.org/10.15252/embr.202051503
https://doi.org/10.15252/embr.202051503
Autor:
Hye-Min Kim, Jong Seog Ahn, In Ja Ryoo, Yang Hoon Huh, Sangku Lee, Jae-Hyuk Jang, Jinyoung Kim, Yong Tae Kwon, Bo Yeon Kim, Nak Kyun Soung, Jin Ok Yang, Eun Joo Song, Kyung Ho Lee, Dong Hyun Kim, Joonsung Hwang, Ho Jin Han, Sung Kyun Ko, Hee Gu Lee, Hyunjoo Cha-Molstad
Publikováno v:
Cell Death and Disease, Vol 10, Iss 8, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
The initiation of centrosome duplication is regulated by the Plk4/STIL/hsSAS-6 axis; however, the involvement of other centrosomal proteins in this process remains unclear. In this study, we demonstrate that Cep131 physically interacts with Plk4 foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f5efc1931b3ca4fa1d151a2e497ae
http://link.springer.com/article/10.1038/s41419-019-1778-8
http://link.springer.com/article/10.1038/s41419-019-1778-8