Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Najmeh Alirezaie"'
Autor:
Cavin Wong, Fei Chen, Najmeh Alirezaie, Yifan Wang, Adeline Cuggia, Ayelet Borgida, Spring Holter, Tatiana Lenko, Celine Domecq, Alzheimer’s Disease Neuroimaging Initiative, Gloria M Petersen, Sapna Syngal, Randall Brand, Anil K Rustgi, Michele L Cote, Elena Stoffel, Sara H Olson, Nicholas J Roberts, Mohammad R Akbari, Jacek Majewski, Alison P Klein, Celia M T Greenwood, Steven Gallinger, George Zogopoulos
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008344 (2019)
Pancreatic adenocarcinoma (PC) is a lethal malignancy that is familial or associated with genetic syndromes in 10% of cases. Gene-based surveillance strategies for at-risk individuals may improve clinical outcomes. However, familial PC (FPC) is plagu
Externí odkaz:
https://doaj.org/article/75b4a65526c94ebcb058060e43896286
Autor:
Maéva Langouët, Christine Jolicoeur, Awais Javed, Pierre Mattar, Micah D. Gearhart, Stephen P. Daiger, Mette Bertelsen, Lisbeth Tranebjærg, Nanna D. Rendtorff, Karen Grønskov, Catherine Jespersgaard, Rui Chen, Zixi Sun, Hui Li, Najmeh Alirezaie, Jacek Majewski, Vivian J. Bardwell, Ruifang Sui, Robert K. Koenekoop, Michel Cayouette
Publikováno v:
Science Advances. 8
Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76424388799c8d3c69b887e5c430c544
https://doi.org/10.1126/sciadv.abh2868
https://doi.org/10.1126/sciadv.abh2868
Autor:
Maéva, Langouët, Christine, Jolicoeur, Awais, Javed, Pierre, Mattar, Micah D, Gearhart, Stephen P, Daiger, Mette, Bertelsen, Lisbeth, Tranebjærg, Nanna D, Rendtorff, Karen, Grønskov, Catherine, Jespersgaard, Rui, Chen, Zixi, Sun, Hui, Li, Najmeh, Alirezaie, Jacek, Majewski, Vivian J, Bardwell, Ruifang, Sui, Robert K, Koenekoop, Michel, Cayouette
Publikováno v:
Science advances. 8(36)
Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1f63ad03990eb0680b90dc00d2333e6
https://pubmed.ncbi.nlm.nih.gov/36070393
https://pubmed.ncbi.nlm.nih.gov/36070393
Autor:
K D Lach, Roni F. Rayes, Jonathan Spicer, Pierre-Olivier Fiset, Logan A. Walsh, Sophie Camilleri-Broët, Benoit Fiset, Najmeh Alirezaie, Jacek Majewski, A Fiore, Mark Sorin, Richard S. Fraser, Caroline Huynh
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 32(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b310f1b8ba89e1950a03e5847e50fc7
https://pubmed.ncbi.nlm.nih.gov/33577994
https://pubmed.ncbi.nlm.nih.gov/33577994
Autor:
Jacek Majewski, Susie Brousse, Josee-Anne Roy, Cristiano Ferrario, Manuela Pelmus, Najmeh Alirezaie, Catalin Mihalcioiu, Cathy Lan, Talia Roseshter, Adriana Aguilar-Mahecha, Eric Bareke, Mohammed Aldamry, Luca Cavallone, Mark Basik, Josiane P. Lafleur, S. Hassan, André Robidoux, Elizabeth A. Marcus, Carole Seguin, Federico Discepola
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Response to neoadjuvant chemotherapy (NAC) in triple negative breast cancer (TNBC) is highly prognostic and determines whether adjuvant chemotherapy is needed if residual tumor is found at surgery. To evaluate the predictive and prognostic values of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb35bf43cf24e44395915c566038fa
http://europepmc.org/articles/PMC7477566
http://europepmc.org/articles/PMC7477566
Publikováno v:
The American Journal of Human Genetics. 103:474-483
Advances in high-throughput DNA sequencing have revolutionized the discovery of variants in the human genome; however, interpreting the phenotypic effects of those variants is still a challenge. While several computational approaches to predict varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87266dce9d550cfdc130f4fd90fc8be3
https://doi.org/10.1016/j.ajhg.2018.08.005
https://doi.org/10.1016/j.ajhg.2018.08.005
Autor:
Taila Hartley, Najmeh Alirezaie, David A. Dyment, Peter N. Robinson, Kym M. Boycott, Kristin D. Kernohan
Publikováno v:
Human Mutation. 39:197-201
A significant challenge facing clinical translation of exome sequencing is meaningful and efficient variant interpretation. Each exome contains ∼500 rare coding variants; laboratories must systematically and efficiently identify which variant(s) co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33c6e91a8c5ed61683319e91ada01de
https://doi.org/10.1002/humu.23374
https://doi.org/10.1002/humu.23374
Autor:
Ashton A. Connor, Alyssa L. Smith, Treasa McPherson, Steven Gallinger, Robert C. Grant, Michelle Chan-Seng-Yue, John Douglas Mcpherson, Ayelet Borgida, Emmanouil Saloustros, Iris Selander, Atilla Omeroglu, Spring Holter, Claire Bascuñana, Thomas Whelan, Sean P. Cleary, Jacek Majewski, Najmeh Alirezaie, Gloria M. Petersen, William D. Foulkes, Anita Hall, Lincoln Stein, George Zogopoulos
Publikováno v:
Cancer letters, vol 370, iss 2
The genetic basis underlying the majority of hereditary pancreatic adenocarcinoma (PC) is unknown. Since DNA repair genes are widely implicated in gastrointestinal malignancies, including PC, we hypothesized that there are novel DNA repair PC suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e0fe385aafa8f857f535544ace228
https://doi.org/10.1016/j.canlet.2015.10.030
https://doi.org/10.1016/j.canlet.2015.10.030
Autor:
Najmeh Alirezaie, Luca Cavallone, Adriana Aguilar-Mahecha, Mohammed Aldamry, Mark Basik, Cathy Lan, Cristiano Ferrario, Pablo Gonzalez Ginestet, Josiane P. Lafleur
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 28(5)
Background: Circulating free DNA (cfDNA) is an exciting novel method to diagnose, monitor, and predict resistance and response to cancer therapies, with the potential to radically alter the management of cancer patients. To fulfill its potential, gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58ebf6ee55a578180620aab504ecceb
https://pubmed.ncbi.nlm.nih.gov/30824523
https://pubmed.ncbi.nlm.nih.gov/30824523
Publikováno v:
Expert Review of Molecular Diagnostics. 15:749-760
Whole-exome sequencing (WES) represents a significant breakthrough in the field of human genetics. This technology has largely contributed to the identification of new disease-causing genes and is now entering clinical laboratories. WES represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bc08ee3b1285868c5218b45998fda5
https://doi.org/10.1586/14737159.2015.1039516
https://doi.org/10.1586/14737159.2015.1039516