Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Najla Kfoury-Beaumont"'
Autor:
Lauren Broestl, Nicole M. Warrington, Lucia Grandison, Tamara Abou-Antoun, Olivia Tung, Saraswati Shenoy, Miranda M. Tallman, Gina Rhee, Wei Yang, Jasmin Sponagel, Lihua Yang, Najla Kfoury-Beaumont, Cameron M. Hill, Sulaiman A. Qanni, Diane D. Mao, Albert H. Kim, Sheila A. Stewart, Monica Venere, Jingqin Luo, Joshua B. Rubin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
In human and murine GBM cells, and wildtype murine astrocytes, radiation induces senescence. Overall, female cells are more sensitive to radiation and to p21-induced senescence. This may contribute to the female survival advantage in GBM.
Externí odkaz:
https://doaj.org/article/4742c6c411eb4925a75c4718df397b65
Autor:
Zongtai Qi, Lauren Broestl, Xuhua Chen, Arnav Moudgil, Sumithra Sankararaman, Michael N. Wilkinson, Joshua B. Rubin, Robi D. Mitra, Jay Gertz, Najla Kfoury-Beaumont, Kristopher Berrett
Publikováno v:
Cancer Research. 80:3658-3658
Sex can be an important determinant of cancer phenotype and exploring sex-specific tumor biology holds promise for identifying novel therapeutic targets and new approaches to cancer treatment. In an established model of glioblastoma, we discovered tr