Human Adipose-Derived Mesenchymal Stem Cells in Cell Therapy: Safety and Feasibility in Different 'Hospital Exemption' Clinical Applications.

Autor: Sophie Vériter, Wivine André, Najima Aouassar, Hélène Antoine Poirel, Aurore Lafosse, Pierre-Louis Docquier, Denis Dufrane

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139566 (2015)

Based on immunomodulatory, osteogenic, and pro-angiogenic properties of adipose-derived stem cells (ASCs), this study aims to assess the safety and efficacy of ASC-derived cell therapies for clinical indications. Two autologous ASC-derived products w

Externí odkaz: https://doaj.org/article/677a3c07d1064df8980560e0d82952c2

Improvement of Pig Islet Function by In Vivo Pancreatic Tissue Remodeling: A 'Human-Like' Pig Islet Structure with Streptozotocin Treatment

Autor: Sophie Vériter, Najima Aouassar, Gwen Beaurin, Rose-Marie Goebbels, Pierre Gianello, Denis Dufrane Ph.D.

Publikováno v: Cell Transplantation, Vol 22 (2013)

Pig islets demonstrate significantly lower insulin secretion after glucose stimulation than human islets (stimulation index of ~12 vs. 2 for glucose 1 and 15 mM, respectively) due to a major difference in β- and α-cell composition in islets (60% an

Externí odkaz: https://doaj.org/article/a69f36fff85a4b68b319bbd860526616

Autologous Adipose Stromal Cells Seeded onto a Human Collagen Matrix for Dermal Regeneration in Chronic Wounds

Autor: Romain Vanwijck, Hélène Poirel, Aurore Lafosse, Wivine André, Marie-Sophie Hanet, Christophe Beauloye, Bernard Gallez, Najima Aouassar, Denis Dufrane, Céline M. Desmet

Publikováno v: Plastic and Reconstructive Surgery. 136:279-295

Nonhealing wounds are unable to integrate skin autografts by avascular and fibrotic dermal tissue. Adipose-derived stromal cells can improve the local environment of the wound bed by angiogenesis and immunomodulation. This work aimed to develop a bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b8e6fe91294ccdfb4912950a0c4e72
https://doi.org/10.1097/prs.0000000000001437

Human Adipose-Derived Mesenchymal Stem Cells in Cell Therapy: Safety and Feasibility in Different 'Hospital Exemption' Clinical Applications

Autor: Najima Aouassar, Denis Dufrane, Wivine André, Aurore Lafosse, Pierre-Louis Docquier, Hélène Poirel, Sophie Vériter

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139566 (2015)
PLoS ONE
PLoS One, Vol. 10, no. 10, p. e0139566 [1-18] (2015)

Based on immunomodulatory, osteogenic, and pro-angiogenic properties of adipose-derived stem cells (ASCs), this study aims to assess the safety and efficacy of ASC-derived cell therapies for clinical indications. Two autologous ASC-derived products w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21dc575ac068955dc8f6b934eb90ddd
http://europepmc.org/articles/PMC4615620?pdf=render

Scaffold-free Three-dimensional Graft From Autologous Adipose-derived Stem Cells for Large Bone Defect Reconstruction

Autor: Najima Aouassar, Pierre-Louis Docquier, Hélène Poirel, Christian Delloye, Denis Dufrane, Wivine André

Publikováno v: Medicine (Baltimore) : analytical reviews of general medicine, neurology, psychiatry, dermatology and pediatrics, Vol. 94, no.50, p. e2220 [1-11] (2015)

Long bone nonunion in the context of congenital pseudarthrosis or carcinologic resection (with intercalary bone allograft implantation) is one of the most challenging pathologies in pediatric orthopedics. Autologous cancellous bone remains the gold s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e8a5a728f67cfaa7d8aa7f8dd25e09
https://doi.org/10.1097/md.0000000000002220