Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Najiba Murad"'
Autor:
Yanxin Pei, Timothy Gershon, Roger Packer, Brian R. Rood, Christopher Lazarski, Peng Zhang, Ulrich Schüller, Dörthe Holdhof, Samuel Rivero-Hinojosa, Ran Tao, Daniel Malawsky, Najiba Murad, Zhenhua Xu
Purpose:Patients with MYC-amplified medulloblastoma (MB) have poor prognosis and frequently develop recurrence, thus new therapeutic approaches to prevent recurrence are needed.Experimental Design:We evaluated OLIG2 expression in a panel of mouse Myc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af1252d551c11161c4630af30f11916
https://doi.org/10.1158/1078-0432.c.6532710.v1
https://doi.org/10.1158/1078-0432.c.6532710.v1
Autor:
Yanxin Pei, Timothy Gershon, Roger Packer, Brian R. Rood, Christopher Lazarski, Peng Zhang, Ulrich Schüller, Dörthe Holdhof, Samuel Rivero-Hinojosa, Ran Tao, Daniel Malawsky, Najiba Murad, Zhenhua Xu
Supplementary Table from OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497ff8ff6b5a025f96f74a9da9104b54
https://doi.org/10.1158/1078-0432.22488399.v1
https://doi.org/10.1158/1078-0432.22488399.v1
Autor:
Yanxin Pei, Timothy Gershon, Roger Packer, Brian R. Rood, Christopher Lazarski, Peng Zhang, Ulrich Schüller, Dörthe Holdhof, Samuel Rivero-Hinojosa, Ran Tao, Daniel Malawsky, Najiba Murad, Zhenhua Xu
Supplementary Data from OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97554cd467bb93b72876b3f207b624d0
https://doi.org/10.1158/1078-0432.22488402.v1
https://doi.org/10.1158/1078-0432.22488402.v1
Autor:
Yanxin Pei, Roger Packer, Brian R. Rood, Charles G. Eberhart, Yang Liu, Pan Zheng, Christopher Lazarski, Samuel Rivero-Hinojosa, Marcel Kool, Konstantin Okonechnikov, Peng Zhang, Zhenhua Xu, Najiba Murad, Ran Tao
RNA-Seq analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a30353dab3b2cf1ce6ba30c183d6200
https://doi.org/10.1158/0008-5472.22423274
https://doi.org/10.1158/0008-5472.22423274
Autor:
Yanxin Pei, Roger Packer, Brian R. Rood, Charles G. Eberhart, Yang Liu, Pan Zheng, Christopher Lazarski, Samuel Rivero-Hinojosa, Marcel Kool, Konstantin Okonechnikov, Peng Zhang, Zhenhua Xu, Najiba Murad, Ran Tao
Figure S1 shows MYC driven tumors generated from early postnatal cerebellar cells. Figure S2 shows IHC staining of tdt+ or tdt- MYC-driven tumors. Figure S3 shows gene expression of mouse MYC-driven tumors compared to that of human medulloblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017350416105333ef3c2530e948defa
https://doi.org/10.1158/0008-5472.22423277.v1
https://doi.org/10.1158/0008-5472.22423277.v1
Autor:
Yanxin Pei, Roger Packer, Brian R. Rood, Charles G. Eberhart, Yang Liu, Pan Zheng, Christopher Lazarski, Samuel Rivero-Hinojosa, Marcel Kool, Konstantin Okonechnikov, Peng Zhang, Zhenhua Xu, Najiba Murad, Ran Tao
A subset of group 3 medulloblastoma frequently harbors amplification or overexpression of MYC lacking additional focal aberrations, yet it remains unclear whether MYC overexpression alone can induce tumorigenesis and which cells give rise to these tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53bd0aaa74edde60fc8a6f2f465ab0fc
https://doi.org/10.1158/0008-5472.c.6511457.v1
https://doi.org/10.1158/0008-5472.c.6511457.v1
Autor:
Zhenhua Xu, Najiba Murad, Daniel Malawsky, Ran Tao, Samuel Rivero-Hinojosa, Dörthe Holdhof, Ulrich Schüller, Peng Zhang, Christopher Lazarski, Brian R. Rood, Roger Packer, Timothy Gershon, Yanxin Pei
Publikováno v:
Clin Cancer Res
Purpose: Patients with MYC-amplified medulloblastoma (MB) have poor prognosis and frequently develop recurrence, thus new therapeutic approaches to prevent recurrence are needed. Experimental Design: We evaluated OLIG2 expression in a panel of mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0ea34443930de9b8e249cb61b40855
https://doi.org/10.1158/1078-0432.ccr-22-0527
https://doi.org/10.1158/1078-0432.ccr-22-0527
Publikováno v:
Neuro-Oncology. 24:i114-i114
Medulloblastoma (MB) is the most common malignant brain tumor in children. There are several subtypes of MB, and among them, the subtype of GLI2-amplified SHH-MB associated with P53 mutations has the worst prognosis and a poor survival rate; the 5-ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc84fae308585cca088faa5231c92e0b
https://doi.org/10.1093/neuonc/noac079.413
https://doi.org/10.1093/neuonc/noac079.413
Autor:
Nady Golestaneh, Karolina J. Janczura, Alexander C. Theos, Mia Gunawan, Nishantha Gunawardena, Najiba Murad, Yetrib Hathout, Maria Kokkinaki
Publikováno v:
FEBS Journal. 281:5251-5264
MicroRNA 184 (miR-184) is known to play a key role in neurological development and apoptosis and is highly expressed in mouse brain, mouse corneal epithelium, zebrafish lens and human retinal pigment epithelium (RPE). However, the role of miR-184 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c77aa08cc2d44f0ee7cda57c968e392
https://doi.org/10.1111/febs.13066
https://doi.org/10.1111/febs.13066
Autor:
Pan Zheng, Christopher A. Lazarski, Roger J. Packer, Konstantin Okonechnikov, Charles G. Eberhart, Yanxin Pei, Brian R. Rood, Peng Zhang, Zhenhua Xu, Najiba Murad, Marcel Kool, Ran Tao, Samuel Rivero-Hinojosa
Publikováno v:
Neuro-Oncology. 20:vi206-vi206
Medulloblastoma (MB) is the most common malignant brain tumor in children. Among the four molecular subgroups of MB (WNT, SHH, Group 3 and Group 4), patients with Group 3 MB exhibit the worst prognosis. Group 3 MB is associated with amplification and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00c50a2dc9c415d0b0d2553c588394f
https://doi.org/10.1093/neuonc/noy148.855
https://doi.org/10.1093/neuonc/noy148.855