Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Najib Lamharzi"'
Autor:
C. B. Renard, Alan Chait, Subramaniam Pennathur, Farah Kramer, Jay W. Heinecke, Najib Lamharzi, Karin E. Bornfeldt
Publikováno v:
Diabetes. 53:3217-3225
Hyperglycemia and hyperlipidemia are important risk factors for diabetes-accelerated atherosclerosis. Macrophage proliferation has been implicated in the progression of atherosclerosis. We therefore investigated the effects of hyperglycemia and hyper
Autor:
Catherine B. Renard, Farah Kramer, Fredrik Johansson, Najib Lamharzi, Lisa R. Tannock, Matthias G. von Herrath, Alan Chait, Karin E. Bornfeldt
Publikováno v:
Journal of Clinical Investigation. 114:659-668
Autor:
Gary E. Goodman, Douglas A. Dightman, Matt J. Barnett, Ruth Etzioni, Noel S. Weiss, Dante DiTommaso, Najib Lamharzi, Chu Chen, Melissa M. Johnson
Publikováno v:
International Journal of Cancer. 105:480-483
In the prostate, the enzyme encoded by the SRD5A2 gene (5α-reductase) converts testosterone to dihydrotestosterone, a potent androgen that has been hypothesized to play a role in the genesis of prostate cancer. Several polymorphisms have been identi
Publikováno v:
Regulatory Peptides. 77:185-192
In previous studies, we showed that LH-RH antagonist Cetrorelix inhibits the growth of DU-145 and PC-3 human androgen-independent prostate cancers in nude mice. To investigate the mechanisms involved, we treated male nude mice bearing xenografts of D
Autor:
M.D.h.c. Andrew V. Schally Ph.D., Miklós Koppán, Gabor Halmos, Najib Lamharzi, José M. Arencibia
Publikováno v:
Cancer. 83:1335-1343
BACKGROUND Antagonists of bombesin/gastrin-releasing peptide (BN/GRP) have been developed to block the autocrine stimulatory effect of BN/GRP on tumors such as small cell lung carcinoma (SCLC). Although several studies have addressed the intracellula
Publikováno v:
Journal of pharmaceutical sciences. 98(2)
Tight junctions (TJs) play an important role in regulating paracellular drug transport. The aim of this study was to identify lipids that rapidly and reversibly alter transepithelial electrical resistance (TER) and/or TJ permeability in epithelial ti
Autor:
Najib, Lamharzi, Catherine B, Renard, Farah, Kramer, Subramaniam, Pennathur, Jay W, Heinecke, Alan, Chait, Karin E, Bornfeldt
Publikováno v:
Diabetes. 53(12)
Hyperglycemia and hyperlipidemia are important risk factors for diabetes-accelerated atherosclerosis. Macrophage proliferation has been implicated in the progression of atherosclerosis. We therefore investigated the effects of hyperglycemia and hyper
Autor:
Catherine B, Renard, Farah, Kramer, Fredrik, Johansson, Najib, Lamharzi, Lisa R, Tannock, Matthias G, von Herrath, Alan, Chait, Karin E, Bornfeldt
Publikováno v:
The Journal of clinical investigation. 114(5)
Diabetes in humans accelerates cardiovascular disease caused by atherosclerosis. The relative contributions of hyperglycemia and dyslipidemia to atherosclerosis in patients with diabetes are not clear, largely because there is a lack of suitable anim
Autor:
Chu, Chen, Najib, Lamharzi, Noel S, Weiss, Ruth, Etzioni, Douglas A, Dightman, Matt, Barnett, Dante, DiTommaso, Gary, Goodman
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 11(10 Pt 1)
The human androgen receptor gene contains polymorphic CAG and GGC repeats in exon 1. We investigated whether the number of CAG and/or GGC repeats is related to prostate cancer risk in a case-control study nested within the beta Carotene and Retinol E
Autor:
Kate Groot, Karoly Szepeshazi, Andrew V. Schally, Masahiro Miyazaki, Najib Lamharzi, Gabor Halmos, Renzhi Cai
Publikováno v:
European journal of cancer (Oxford, England : 1990). 34(5)
Bombesin or gastrin-releasing peptide (GRP) may act as autocrine growth factors and play a role in the initiation and progression of breast cancer. We investigated the effect of bombesin/GRP antagonists RC-3095 and RC-3940-II on the growth of the MDA