Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Najib Ben-Khaled"'
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101146- (2024)
Externí odkaz:
https://doaj.org/article/eda705a60378498ea328a83cd6d0fa87
Autor:
Najib Ben Khaled, Marie Möller, Leonie S. Jochheim, Catherine Leyh, Ursula Ehmer, Katrin Böttcher, Matthias Pinter, Lorenz Balcar, Bernhard Scheiner, Alexander Weich, Hans Benno Leicht, Valentina Zarka, Liangtao Ye, Julia Schneider, Ignazio Piseddu, Osman Öcal, Monika Rau, Friedrich Sinner, Marino Venerito, Simon Johannes Gairing, Friedrich Förster, Julia Mayerle, Enrico N. De Toni, Andreas Geier, Florian P. Reiter
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101065- (2024)
Background & Aims: Atezolizumab/bevacizumab (atezo/bev) and lenvatinib have demonstrated efficacy as first-line therapies for hepatocellular carcinoma (HCC). However, vascular endothelial growth factor (VEGF) inhibition with these therapies may be as
Externí odkaz:
https://doaj.org/article/8bfa5b4342fd47ce9b2a38f731714629
Autor:
Lukas Salvermoser, Shraga Nahum Goldberg, Marianna Alunni-Fabbroni, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Jan Niklas Schäfer, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Agnese Petrera, Moritz Wildgruber, Jens Ricke, Matthias Stechele
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101919- (2024)
Background and purpose: To determine the potential prognostic value of proliferation and angiogenesis plasma proteins following CT-guided high dose rate brachytherapy (HDR-BT) of hepatocellular carcinoma (HCC). Materials and methods: For this prospec
Externí odkaz:
https://doaj.org/article/e502db2844e34e4889c28dccac3bccce
Autor:
Osman Öcal, Melanie Alexandra Kimm, Thi Phuong Thao Hoang, Maciej Pech, Elif Öcal, Najib Ben Khaled, Bruno Sangro, Jens Ricke, Max Seidensticker, Moritz Wildgruber
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 100995- (2024)
Background & Aims: Herein we used data derived from the SORAMIC trial to explore the predictive value of systemic inflammatory markers (neutrophil-to-lymphocyte ratio [NLR] and platelet-to-lymphocyte ratio [PLR]) in patients with advanced hepatocellu
Externí odkaz:
https://doaj.org/article/820fb76b343f4343ab7f9a3758e6e209
Autor:
Matthias Stechele, Henrike Link, Heidrun Hirner-Eppeneder, Marianna Alunni-Fabbroni, Moritz Wildgruber, Lukas Salvermoser, Stefanie Corradini, Regina Schinner, Najib Ben Khaled, Daniel Rössler, Eithan Galun, Shraga Nahum Goldberg, Jens Ricke, Philipp Maximilian Kazmierczak
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background and aims Prognostic biomarkers identifying patients with early tumor progression after local ablative therapy remain an unmet clinical need. The aim of this study was to investigate circulating miR-21 and miR-210 levels as prognos
Externí odkaz:
https://doaj.org/article/eb3d799600814c94ad98f86d90d10822
Autor:
Sebastian Mönch, Maurice M. Heimer, Michael Winkelmann, Anne Guertler, Max Schlaak, Amanda Tufman, Najib Ben Khaled, Enrico de Toni, Christoph B. Westphalen, Michael von Bergwelt-Baildon, Julien Dinkel, Philipp M. Kazmierczak, Michael Ingrisch, Nabeel Mansour, Marcus Unterrainer, Lucie Heinzerling, Jens Ricke, Wolfgang G. Kunz
Publikováno v:
Cancer Imaging, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Pseudoprogression (PsPD) is a rare response pattern to immune checkpoint inhibitor (ICI) therapy in oncology. This study aims to reveal imaging features of PsPD, and their association to other relevant findings. Methods Patients w
Externí odkaz:
https://doaj.org/article/2c2fcfaf0c564e3e9f88c328dca83c52
Autor:
Jan Rudolph, Balthasar Schachtner, Nicola Fink, Vanessa Koliogiannis, Vincent Schwarze, Sophia Goller, Lena Trappmann, Boj F. Hoppe, Nabeel Mansour, Maximilian Fischer, Najib Ben Khaled, Maximilian Jörgens, Julien Dinkel, Wolfgang G. Kunz, Jens Ricke, Michael Ingrisch, Bastian O. Sabel, Johannes Rueckel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Artificial intelligence (AI) algorithms evaluating [supine] chest radiographs ([S]CXRs) have remarkably increased in number recently. Since training and validation are often performed on subsets of the same overall dataset, external validati
Externí odkaz:
https://doaj.org/article/ad5365621b25497093f989c0ffc4da95
Autor:
Max Seidensticker, Osman Öcal, Kerstin Schütte, Peter Malfertheiner, Thomas Berg, Christian Loewe, Heinz Josef Klümpen, Otto van Delden, Muzaffer Reha Ümütlü, Najib Ben Khaled, Enrico Narciso de Toni, Ricarda Seidensticker, Ali Aghdassi, Albert Tran, Jean-Pierre Bronowicki, Bora Peynircioglu, Bruno Sangro, Maciej Pech, Jens Ricke
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100699- (2023)
Background & Aims: The aim of the study was to evaluate the efficacy and safety of adjuvant sorafenib treatment compared with placebo in patients with hepatocellular carcinoma who underwent local ablation. Methods: The SORAMIC trial is a randomised c
Externí odkaz:
https://doaj.org/article/50507419bb5c4a48b92f62fe7087d683
Autor:
Florian P. Reiter, Liangtao Ye, Andrea Ofner, Tobias S. Schiergens, Andreas Ziesch, Lydia Brandl, Najib Ben Khaled, Simon Hohenester, Ralf Wimmer, Renate Artmann, Yulong He, Serene M.L. Lee, Doris Mayr, Changhua Zhang, Alexander L. Gerbes, Julia Mayerle, Gerald Denk, Enrico N. De Toni
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 95-112 (2022)
Background & Aims: Progression of chronic liver disease (CLD) to liver cirrhosis and liver cancer is a major global cause of morbidity and mortality. Treatment options capable of inhibiting progression of liver fibrosis when etiological treatment of
Externí odkaz:
https://doaj.org/article/d5c1e3f3e4744b00bcc68fbf2299c769
Autor:
Liangtao Ye, Julia S. Schneider, Najib Ben Khaled, Peter Schirmacher, Carolin Seifert, Lea Frey, Yulong He, Andreas Geier, Enrico N. De Toni, Changhua Zhang, Florian P. Reiter
Publikováno v:
Liver Cancer, Pp 1-1 (2023)
Background Combined hepatocellular-cholangiocarcinoma (cHCC-iCCA) is a rare type of primary liver cancer displaying characteristics of both hepatocytic and cholangiocytic differentiation. Summary Because of its aggressive nature, patients with cHCC-i
Externí odkaz:
https://doaj.org/article/7dcff6221e134cee91cd6d3df1483672