Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Najet Srairi Abid"'
Autor:
Nour-elhouda Neili, Zaineb AbdelKafi-Koubaa, Jed Jebali, Khouloud Kaidi, Ghada Sahraoui, Melika Ben Ahmed, Najet Srairi-Abid, Naziha Marrakchi, Raoudha Doghri, Ines ELBini
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Several neurodegenerative diseases, such as multiple sclerosis and Parkinson’s disease, are linked to alterations in myelin content or structure. Transmembrane receptors such as integrins could be involved in these alterations. In the pres
Externí odkaz:
https://doaj.org/article/e33fe32871b24e25b2cae58504b7b33c
Autor:
Imen Abid, Wassim Moslah, Sandrine Cojean, Nicolas Imbert, Philippe M. Loiseau, Alain Chamayou, Najet Srairi-Abid, Rachel Calvet, Michel Baltas
Publikováno v:
Molecules, Vol 29, Iss 8, p 1819 (2024)
Chalcones are polyphenols that belong to the flavonoids family, known for their broad pharmacological properties. They have thus attracted the attention of chemists for their obtention and potential activities. In our study, a library of compounds fr
Externí odkaz:
https://doaj.org/article/a215fd4116c84482854ed5217bac3c76
Autor:
Cyrine Souissi, Soumaya Marzouki, Ines Elbini-Dhouib, Jed Jebali, Fabiano Oliveira, Jesus G. Valenzuela, Najet Srairi-Abid, Shaden Kamhawi, Melika Ben Ahmed
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background The saliva of sand flies, vectors of Leishmania parasites, contains several components that exert pharmacological activity facilitating the acquisition of blood by the insect and contributing to the establishment of infection. Pre
Externí odkaz:
https://doaj.org/article/8cf4f36db80648c89b5e03a6dd50d4c2
Autor:
Saoussen Mlayah-Bellalouna, Dorra Aissaoui-Zid, Aurelie Chantome, Jed Jebali, Soumaya Souid, Emna Ayedi, Hafedh Mejdoub, Maya Belghazi, Naziha Marrakchi, Khadija Essafi-Benkhadir, Christophe Vandier, Najet Srairi-Abid
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The emerging concept of small conductance Ca2+-activated potassium channels (SKCa) as pharmacological target for cancer treatment has significantly increased in recent years. In this study, we isolated the P01 toxin from Androctonus australis (Aa) sc
Externí odkaz:
https://doaj.org/article/d4c991e53bfe45dea0b59b56dd54827c
Autor:
Aida Jlassi, Maroua Manai, Maram Morjen, Ghada Sahraoui, Monia Elasmi Allal, Ines ELBini-Dhouib, Lamia Naija, Lamia Charfi, Rim Rejaibi, Melika Ben Ahmed, Naziha Marrakchi, Najet Srairi-Abid, Amel Mezlini, Mohamed Manai, Karima Mrad, Raoudha Doghri
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0278849 (2023)
Immunotherapy by blocking immune checkpoint regulators has emerged as a new targeted therapy for some cancers. Among them V-domain Ig suppressor of Tcell activation (VISTA) which is identified as a novel checkpoint regulator in ovarian cancer. This s
Externí odkaz:
https://doaj.org/article/376c2063d6374966ae4a76ec9738ef8c
Autor:
Abir Jlassi, Marwa Mekni-Toujani, Asma Ferchichi, Charfeddine Gharsallah, Christian Malosse, Julia Chamot-Rooke, Mohamed ElAyeb, Abdeljelil Ghram, Najet Srairi-Abid, Salma Daoud
Publikováno v:
Molecules, Vol 28, Iss 11, p 4355 (2023)
Newcastle disease virus (NDV) is one of the most serious contagions affecting domestic poultry and other avian species. It causes high morbidity and mortality, resulting in huge economic losses to the poultry industry worldwide. Despite vaccination,
Externí odkaz:
https://doaj.org/article/17a6749bf3b2498a937f010d0c979d70
Autor:
Houcemeddine Othman, Haifa Ben Messaoud, Oussema Khamessi, Hazem Ben-Mabrouk, Kais Ghedira, Avani Bharuthram, Florette Treurnicht, Ikechukwu Achilonu, Yasien Sayed, Najet Srairi-Abid
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The Receptor Binding Domain (RBD) of SARS-CoV-2 virus harbors a sequence of Arg-Gly-Asp tripeptide named RGD motif, which has also been identified in extracellular matrix proteins that bind integrins as well as other disintegrins and viruses. Accordi
Externí odkaz:
https://doaj.org/article/fdff8a5d08414ce8853d2f9ba4b63f69
Autor:
Rym ElFessi, Oussema Khamessi, Najet Srairi-Abid, Jean-Marc Sabatier, Jan Tytgat, Steve Peigneur, Riadh Kharrat
Publikováno v:
Molecules, Vol 27, Iss 21, p 7278 (2022)
Scorpion venom is a rich source of promising therapeutic compounds, such as highly selective ion channel ligands with potent pharmacological effects. Bot33 is a new short polypeptide of 38 amino acid residues with six cysteines purified from the veno
Externí odkaz:
https://doaj.org/article/43bed0d6468e4a90a1391ef6f819754a
Autor:
Maroua Manai, Ines ELBini-Dhouib, Pascal Finetti, Haifa Bichiou, Carolina Reduzzi, Dorra Aissaoui, Naziha Ben-Hamida, Emilie Agavnian, Najet Srairi-Abid, Marc Lopez, Fatma Amri, Lamia Guizani-Tabbane, Khaled Rahal, Karima Mrad, Mohamed Manai, Daniel Birnbaum, Emilie Mamessier, Massimo Cristofanilli, Hamouda Boussen, Maher Kharrat, Raoudha Doghri, François Bertucci
Publikováno v:
Cells, Vol 11, Iss 18, p 2926 (2022)
Inflammatory breast cancer (IBC) is the most pro-metastatic form of breast cancer (BC). We previously demonstrated that protein overexpression of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) protein was associated with shorter survival in I
Externí odkaz:
https://doaj.org/article/f0bd0446e84446379a1c35782ae0f216
Autor:
Zaineb Abdelkafi-Koubaa, Imen Aissa, Hichem Ben Jannet, Najet Srairi-Abid, Naziha Marrakchi, Samia Menif
Publikováno v:
Molecules, Vol 27, Iss 16, p 5086 (2022)
In the present study, we assess tyrosol derivatives bearing 3,5-disubstituted isoxazoles and 1,4-disubstituted triazoles for their ability to inhibit the proliferation of K562 cells derived from leukemia as well as primary chronic myeloid leukemia (C
Externí odkaz:
https://doaj.org/article/347e41a799e44221a0412bc3d2c9b529