A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Autor: Wojtaszek, Jessica L., Chatterjee, Nimrat, Najeeb, Javaria, Ramos, Azucena, Lee, Minhee, Bian, Ke, Xue, Jenny Y., Fenton, Benjamin A., Park, Hyeri, Li, Deyu, Hemann, Michael T., Hong, Jiyong, Walker, Graham C., Zhou, Pei

Publikováno v: In Cell 27 June 2019 178(1):152-159

Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2

Autor: Nielsen, Sandra C.A., Yang, Fan, Jackson, Katherine J.L., Hoh, Ramona A., Röltgen, Katharina, Jean, Grace H., Stevens, Bryan A., Lee, Ji-Yeun, Rustagi, Arjun, Rogers, Angela J., Powell, Abigail E., Hunter, Molly, Najeeb, Javaria, Otrelo-Cardoso, Ana R., Yost, Kathryn E., Daniel, Bence, Nadeau, Kari C., Chang, Howard Y., Satpathy, Ansuman T., Jardetzky, Theodore S., Kim, Peter S., Wang, Taia T., Pinsky, Benjamin A., Blish, Catherine A., Boyd, Scott D.

Publikováno v: In Cell Host & Microbe 7 October 2020 28(4):516-525

Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC

Autor: Lemaître, Nadine, Liang, Xiaofei, Najeeb, Javaria, Lee, Chul-Jin, Titecat, Marie, Leteurtre, Emmanuelle, Simonet, Michel, Toone, Eric J., Zhou, Pei, Sebbane, Florent

Publikováno v: mBio
mBio, Vol 8, Iss 4 (2017)

The infectious diseases caused by multidrug-resistant bacteria pose serious threats to humankind. It has been suggested that an antibiotic targeting LpxC of the lipid A biosynthetic pathway in Gram-negative bacteria is a promising strategy for curing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e3c83ce3b5067c518f75c55bb8cbc39
http://europepmc.org/articles/PMC5527309

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness.

Autor: Röltgen K; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Wirz OF; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Stevens BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Powell AE; Stanford ChEM-H and Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Hogan CA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Najeeb J; Department of Structural Biology, Stanford University, Stanford, USA., Hunter M; ATUM, Newark, CA, USA., Sahoo MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Huang C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Yamamoto F; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Manalac J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Otrelo-Cardoso AR; Department of Structural Biology, Stanford University, Stanford, USA., Pham TD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Blood Center, Palo Alto, CA, USA., Rustagi A; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA., Rogers AJ; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, CA, USA., Shah NH; Stanford Center for Biomedical Informatics Research, Stanford University, Stanford, California, USA., Blish CA; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Cochran JR; Department of Bioengineering, Stanford University, Stanford, CA, USA., Nadeau KC; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, CA, USA.; Sean N. Parker Center for Allergy and Asthma Research, Stanford, CA, USA., Jardetzky TS; Department of Structural Biology, Stanford University, Stanford, USA., Zehnder JL; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Wang TT; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Kim PS; Stanford ChEM-H and Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Gombar S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Tibshirani R; Department of Biomedical Data Sciences, Stanford University, Stanford, CA, USA.; Department of Statistics, Stanford University, Stanford, CA, USA., Pinsky BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA., Boyd SD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sean N. Parker Center for Allergy and Asthma Research, Stanford, CA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2020 Aug 17. Date of Electronic Publication: 2020 Aug 17.