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pro vyhledávání: '"Najd M. Aljadeed"'
Autor:
Stuart Leishman, Najd M. Aljadeed, Liyunhe Qian, Shamshad Cockcroft, Jacques Behmoaras, Paras K. Anand
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114516- (2024)
Summary: Despite its significance, the role of lipid metabolism in NLRP3 inflammasome remains elusive. Here, we reveal a critical role for fatty acid synthase (FASN) in NLRP3 inflammasome activation. We demonstrate that pharmacological or genetic dep
Externí odkaz:
https://doaj.org/article/7df8d54df58543839723b9bca08ac6c3
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103054- (2024)
Summary: Palmitoylation is a post-translational lipid modification in which palmitic acid is conjugated predominantly to cysteine residues of target proteins, allowing them to tether to cell membranes. Here, we describe a protocol to perform a stepwi
Externí odkaz:
https://doaj.org/article/3ef68d8961794b4792e29926352ea975