Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Naja Zenius, Jespersen"'
Autor:
Christian Schlein, Alexander W. Fischer, Frederike Sass, Anna Worthmann, Klaus Tödter, Michelle Y. Jaeckstein, Janina Behrens, Matthew D. Lynes, Michael A. Kiebish, Niven R. Narain, Val Bussberg, Abena Darkwah, Naja Zenius Jespersen, Søren Nielsen, Camilla Scheele, Michaela Schweizer, Ingke Braren, Alexander Bartelt, Yu-Hua Tseng, Joerg Heeren, Ludger Scheja
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108624- (2021)
Summary: Thermoneutral conditions typical for standard human living environments result in brown adipose tissue (BAT) involution, characterized by decreased mitochondrial mass and increased lipid deposition. Low BAT activity is associated with poor m
Externí odkaz:
https://doaj.org/article/8ed0fd3d09e243ad800cc875dc39ea85
Autor:
Ryutaro Ikegami, Ippei Shimizu, Takeshi Sato, Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Ji Li, Takayuki Wakasugi, Yasuhiko Minokoshi, Shiki Okamoto, Eiichi Hinoi, Søren Nielsen, Naja Zenius Jespersen, Camilla Scheele, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2827-2837.e5 (2018)
Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the maintenance of systemic metabolism. The sympathetic nervous system plays important roles in the homeostasis of BAT and promotes its browning and activation. H
Externí odkaz:
https://doaj.org/article/4f53263889c44265b7fe4c96e644b256
Autor:
Sajjad Khani, Hande Topel, Ajeetha Josephrajan, Bjørk Ditlev Marcher Larsen, Ana Rita Albuquerque de Almeida Tavanez, Michael James Gaudry, Philipp Leyendecker, Natasa Stanic, Isabella Gaziano, Nils Rouven Hansmeier, Elena Schmidt, Paul Klemm, Lara-Marie Vagliano, Christoph Andreas Engelhard, Søren Nielsen, Naja Zenius Jespersen, Rizwan Rehimi, Sabrina Gohlke, Peter Frommolt, Thorsten Gnad, Alvaro Rada-Iglesias, Marta Pradas-Juni, Tim Julius Schulz, Frank Thomas Wunderlich, Alexander Pfeifer, Martin Jastroch, Dagmar Wachten, Jan-Wilhelm Kornfeld
Promoting brown adipose tissue (BAT) activity has been recognized as innovative therapeutic approach to improve obesity and metabolic disease. Whilst the molecular circuitry underlying thermogenic activation of BAT is well understood, the processes u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d092b5818b47d49297399104bc4b2dce
https://doi.org/10.1101/2022.08.01.502156
https://doi.org/10.1101/2022.08.01.502156
Autor:
Yuka Hayashi, Ippei Shimizu, Yohko Yoshida, Ryutaro Ikegami, Masayoshi Suda, Goro Katsuumi, Shinya Fujiki, Kazuyuki Ozaki, Manabu Abe, Kenji Sakimura, Shujiro Okuda, Toshiya Hayano, Kazuhiro Nakamura, Kenneth Walsh, Naja Zenius Jespersen, Søren Nielsen, Camilla Scheele, Tohru Minamino
Publikováno v:
Hayashi, Y, Shimizu, I, Yoshida, Y, Ikegami, R, Suda, M, Katsuumi, G, Fujiki, S, Ozaki, K, Abe, M, Sakimura, K, Okuda, S, Hayano, T, Nakamura, K, Walsh, K, Jespersen, N Z, Nielsen, S, Scheele, C & Minamino, T 2022, ' Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity ', iScience, vol. 25, no. 7, 104547 . https://doi.org/10.1016/j.isci.2022.104547
Brown adipose tissue (BAT) has a role in maintaining systemic metabolic health in rodents and humans. Here, we show that metabolic stress induces BAT to produce coagulation factors, which then—together with molecules derived from the circulation—
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541f1a82c190f0351cc2cc839c61c094
https://doi.org/10.1016/j.isci.2022.104547
https://doi.org/10.1016/j.isci.2022.104547
Autor:
Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer
Publikováno v:
Cell Metabolism. 34:649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88374ca60195ccaeb99d40f2e4d656b7
https://doi.org/10.1016/j.cmet.2022.02.014
https://doi.org/10.1016/j.cmet.2022.02.014
Publikováno v:
Handbook of experimental pharmacology. 251
Obesity involves a contrasting expansion of the energy-storing white fat and loss of functionally competent brown fat, an energy-consuming thermogenic adipose. Leveraging our understanding of white and brown adipocyte recruitment and investigating fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb27a8918a56017901fba992ff9f068b
https://pubmed.ncbi.nlm.nih.gov/29980911
https://pubmed.ncbi.nlm.nih.gov/29980911