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of 6
pro vyhledávání: '"Naja Nyffenegger"'
Autor:
Naja Nyffenegger, Anna Flace, Ahmet Varol, Patrick Altermatt, Cédric Doucerain, Hanna Sundstrom, Franz Dürrenberger, Vania Manolova
Publikováno v:
HemaSphere, Vol 8, Iss 9, Pp n/a-n/a (2024)
Abstract Hemochromatosis is an inherited iron overload condition caused by mutations that reduce the levels of the iron‐regulatory hormone hepcidin or its binding to ferroportin. The hepcidin–ferroportin axis is pivotal to iron homeostasis, provi
Externí odkaz:
https://doaj.org/article/6275d404ed394da882c80dfa9aa97074
Autor:
Natarajaswamy Kalleda, Anna Flace, Patrick Altermatt, Giada Ingoglia, Cédric Doucerain, Naja Nyffenegger, Franz Dürrenberger, Vania Manolova
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
β-thalassemia is an inherited anemia characterized by ineffective erythropoiesis. Blood transfusions are required for survival in transfusion-dependent β-thalassemia and are also occasionally needed in patients with non-transfusion-dependent β-tha
Externí odkaz:
https://doaj.org/article/686e445672b24fec97d5bcd135b5cf04
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 873 (2021)
In β-thalassemia, ineffective erythropoiesis leads to anemia and systemic iron overload. The management of iron overload by chelation therapy is a standard of care. However, iron chelation does not improve the ineffective erythropoiesis. We recently
Externí odkaz:
https://doaj.org/article/40cf6a31c7f14c3c8d9c23397c82bc51
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 873, p 873 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 873, p 873 (2021)
In &beta
thalassemia, ineffective erythropoiesis leads to anemia and systemic iron overload. The management of iron overload by chelation therapy is a standard of care. However, iron chelation does not improve the ineffective erythropoiesis. We
thalassemia, ineffective erythropoiesis leads to anemia and systemic iron overload. The management of iron overload by chelation therapy is a standard of care. However, iron chelation does not improve the ineffective erythropoiesis. We
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 174
Intravenously administered iron-carbohydrate preparations are a structurally heterogenous class of nanomedicines. Iron biodistribution to target tissues is greatly affected by the physicochemical characteristics of these nanoparticles. Some regulator
Autor:
Vania Manolova, Cédric Doucerain, Naja Nyffenegger, Franz Dürrenberger, Patrick Altermatt, Hanna Sundström, Anna Flace, Ahmet Varol
β-Thalassemia is a genetic anemia caused by partial or complete loss of β-globin synthesis, leading to ineffective erythropoiesis and RBCs with a short life span. Currently, there is no efficacious oral medication modifying anemia for patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4b3a46cb567309b695aa494591182a
https://europepmc.org/articles/PMC6934209/
https://europepmc.org/articles/PMC6934209/