A novel antibody combination to identify KIR2DS2(high) NK cells in KIR2DL3/L2/S2 heterozygous donors

Autor: Blunt, Matthew, Rettman, Pauline, Bastidas Legarda, Leidy, Yamile, Fulton, Rebecca, Capizzuto, Valentino, Naiyer, Mohammed M, Traherne, James A., Khakoo, Salim

The killer cell immunoglobulin‐like receptor (KIR) KIR2DS2 induces NK cell activation upon ligation and in genetic studies is associated with protection against certain cancers and viral infections. One of the difficulties in understanding KIR2DS2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______348::b2d6cb05fcdedbc63e54b7cecdd2586a
https://eprints.soton.ac.uk/425953/

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Autor: Naiyer, Mohammed M., Cassidy, Sorcha A., Magri, Andrea, Cowton, Vanessa, Chen, Kevin, Mansour, Salah, Kranidioti, Hariklia, Mbirbindi, Berenice, Rettman, Pauline, Harris, Scott, Fanning, Liam J., Mulder, Arend, Claas, Franz H.J., Davidson, Andrew D., Patel, Arvind H., Purbhoo, Marco A., Khakoo, Salim I.

Publikováno v: Naiyer, M M, Cassidy, S A, Magri, A, Cowton, V, Chen, K, Mansour, S, Kranidioti, H, Mbirbindi, B, Rettman, P, Harris, S, Fanning, L J, Mulder, A, Claas, F H J, Davidson, A D, Patel, A H, Purbhoo, M A & Khakoo, S I 2017, ' KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C ', Science Immunology, vol. 2, no. 15, eaal5296 . https://doi.org/10.1126/sciimmunol.aal5296

Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural killer (NK) cell receptors associated with protection against multiple different human viral infections. We report that the activating receptor KIR2DS2 dir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0ea325e3136b29582e863ead5a43d058
https://eprints.soton.ac.uk/414342/

A novel antibody combination to identify KIR2DS2^high natural killer cells in KIR2DL3/L2/S2 heterozygous donors.

Autor: Blunt, Matthew D., Rettman, Pauline, Bastidas‐Legarda, Leidy Y., Fulton, Rebecca, Capizzuto, Valentina, Naiyer, Mohammed M., Khakoo, Salim I., Traherne, James A.

Publikováno v: HLA: Immune Response Genetics; Jan2019, Vol. 93 Issue 1, p32-35, 4p, 2 Graphs

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