Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response.

Autor: Li W; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. wanjinli@sioc.ac.cn.; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. wanjinli@sioc.ac.cn., Shan B; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Zou C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Wang H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Zhang MM; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Zhu H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Naito MG; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Xu D; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Manuel VJ; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Mifflin L; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Hou Z; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Ravits J; ALS Translational Research Program, Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA., Yuan J; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. junying_yuan@sioc.ac.cn.; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. junying_yuan@sioc.ac.cn.

Publikováno v: Cell research [Cell Res] 2022 Jul; Vol. 32 (7), pp. 621-637. Date of Electronic Publication: 2022 Jun 03.

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.

Autor: Xu D; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Zhao H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Jin M; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Zhu H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Shan B; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Geng J; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Dziedzic SA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Amin P; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Mifflin L; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Naito MG; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Najafov A; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Xing J; Department of Pediatrics and Human Development, Michigan State University, Grand Rapids, MI, USA., Yan L; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Liu J; State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Qin Y; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Hu X; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Wang H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Zhang M; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Manuel VJ; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Tan L; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., He Z; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.; Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Sun ZJ; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA., Lee VMY; Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Wagner G; Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Yuan J; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. junying_yuan@hms.harvard.edu.

Publikováno v: Nature [Nature] 2020 Nov; Vol. 587 (7832), pp. 133-138. Date of Electronic Publication: 2020 Sep 23.

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.

Autor: Xu D; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Jin T; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China; University of Chinese Academy of Sciences, 100049 Beijing, China., Zhu H; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Chen H; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Ofengeim D; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Zou C; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Mifflin L; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Pan L; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Rd., 200032 Shanghai, China., Amin P; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Li W; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Shan B; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China., Naito MG; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA., Meng H; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China; University of Chinese Academy of Sciences, 100049 Beijing, China., Li Y; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China., Pan H; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China., Aron L; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Adiconis X; Broad Institute, Cambridge, MA 02142, USA., Levin JZ; Broad Institute, Cambridge, MA 02142, USA., Yankner BA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Yuan J; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China. Electronic address: jyuan@hms.harvard.edu.

Publikováno v: Cell [Cell] 2018 Sep 06; Vol. 174 (6), pp. 1477-1491.e19. Date of Electronic Publication: 2018 Aug 23.