Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nairi, Pezeshkian"'
Autor:
Carmen A. Buttler, Nairi Pezeshkian, Melissa V. Fernandez, Jesse Aaron, Sofya Norman, Eric O. Freed, Schuyler B. van Engelenburg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-assoc
Externí odkaz:
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
Autor:
Huxley K. Hoffman, Rebekah S. Aguilar, Austin R. Clark, Nicholas S. Groves, Nairi Pezeshkian, Merissa M. Bruns, Schuyler B. van Engelenburg
Publikováno v:
Journal of Virology. 96
HIV-1 envelope glycoprotein (Env) evades immune neutralization through many mechanisms. One immune evasion strategy may result from the internalization of excess surface-exposed Env to prevent antibody-dependent cellular cytotoxicity or neutralizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a8ed7514411f2e3b2316a5bfa2dd8ff
https://doi.org/10.1128/jvi.00767-22
https://doi.org/10.1128/jvi.00767-22
Publikováno v:
Cancer Research. 83:6522-6522
Ovarian and endometrial cancers come within the top-4 for incident cancers as well as deaths in North American women. Cure rates have not improved in 30 years as high-grade subtypes continue to be diagnosed in Stage III/IV. Attempts at early diagnosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63b120ad459721272caa37d5b773246
https://doi.org/10.1158/1538-7445.am2023-6522
https://doi.org/10.1158/1538-7445.am2023-6522
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To create an infectious HIV-1 particle, the envelope glycoprotein (Env) must find a budding virus assembly site on the surface of an infected cell. Assembly sites are composed of growing 2-dimensional lattices of the structural Gag prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524d49efb82fab2e7f2ac7e1abf971a6
https://doi.org/10.1073/pnas.1910008116
https://doi.org/10.1073/pnas.1910008116
Autor:
Melissa V. Fernandez, Eric O. Freed, Schuyler B. van Engelenburg, Nairi Pezeshkian, Huxley K. Hoffman, Philip R. Tedbury
Publikováno v:
J Virol
HIV-1 encodes an envelope glycoprotein (Env) that contains a long cytoplasmic tail (CT) harboring trafficking motifs implicated in Env incorporation into virus particles and viral transmission. In most physiologically relevant cell types, the gp41 CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4fb93a626d2c3f374febc503ca5426
https://europepmc.org/articles/PMC7654282/
https://europepmc.org/articles/PMC7654282/
Autor:
Jesse Aaron, Schuyler B. van Engelenburg, Melissa V. Fernandez, Nairi Pezeshkian, Carmen A. Buttler, Sofya Norman, Eric O. Freed
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
Human immunodeficiency virus type 1 (HIV-1) assembly occurs on the inner leaflet of the host cell plasma membrane, incorporating the essential viral envelope glycoprotein (Env) within a budding lattice of HIV-1 Gag structural proteins. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c6f9da7e564d6ffcbb15129ddb9899
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
Publikováno v:
Biophysical Journal. 118:57a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f1cd924ba0f708f4b7dbd2e5020a51
https://doi.org/10.1016/j.bpj.2019.11.490
https://doi.org/10.1016/j.bpj.2019.11.490