Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Naira Samarina"'
Autor:
Ibiayi Dagogo-Jack, MD, Ivan Valiev, MD, Nikita Kotlov, MS, Anna Belozerova, MD, Aleksandra Lopareva, MS, MD, Anna Butusova, MS, Naira Samarina, PhD, Alexandra Boyko, MS, Zhongmin Xiang, PhD, Monique Johnson, BS, Sandrine Degryse, PhD, Florence K. Keane, MD, Lecia V. Sequist, MD, Michael Lanuti, MD, Nathan Fowler, MD, Mari Mino-Kenudson, MD, Alexander Bagaev, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 7, Pp 100527- (2023)
Introduction: Relapse is common after resection of lung adenocarcinoma (LUAD). Features of the tumor microenvironment (TME) which influence postsurgical survival outcomes are poorly characterized. Here, we analyzed the TME of more than 1500 LUAD spec
Externí odkaz:
https://doaj.org/article/acbc54d5c39b41eeb5768d2ee56dbc4c
Autor:
Cora N. Sternberg, Nara Shin, Konstantin Chernyshov, Fabio Calabro, Linda Cerbone, Giuseppe Procopio, Natalia Miheecheva, Georgy Sagaradze, Alisa Zaichikova, Naira Samarina, Alexandra Boyko, Jessica H. Brown, Leysan Yunusova, Daniela Guevara, Jyothi Manohar, Michael Sigouros, Majd Al Assaad, Olivier Elemento, Juan Miguel Mosquera
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Although immune checkpoint inhibitors (ICIs) are increasingly used as second-line treatments for urothelial cancer (UC), only a small proportion of patients respond. Therefore, understanding the mechanisms of response to ICIs is critical to improve c
Externí odkaz:
https://doaj.org/article/261fadd6de394c4e909ca5e76ae4df64
Autor:
Naira Samarina, George Ssebyatika, Tanvi Tikla, Ja-Yun Waldmann, Bizunesh Abere, Vittoria Nanna, Michelangelo Marasco, Teresa Carlomagno, Thomas Krey, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009635 (2021)
Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of multicentric Castleman's Disease (MCD), as well as an inflammatory cytokine syndrome (KI
Externí odkaz:
https://doaj.org/article/5bd22e854467486fb7a9d993ffd4e8b5
Autor:
Bizunesh Abere, Tamrat M Mamo, Silke Hartmann, Naira Samarina, Elias Hage, Jessica Rückert, Sven-Kevin Hotop, Guntram Büsche, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006639 (2017)
Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious cause of the highly vascularized tumor Kaposi's sarcoma (KS), which is characterized by proliferating spindle cells of endothelial origin, extensive neo-angiogenesis and inflammatory in
Externí odkaz:
https://doaj.org/article/8b0f53f027334d17a85522dc38174863
Autor:
Majd Al Assaad, Michael Sigouros, Jyothi Manohar, Daniela Guevara, Zoia Antysheva, Daria Kiriy, Alexandra Boyko, Naira Samarina, Nara Shin, Viktor Svekolkin, Svetlana Podsvirova, Noel English, Alaina Villarreal, Brianna McKenna, Cagdas Tazearslan, Diana Shamsutdinova, Vladimir Kushnarev, Troy Kane, David Wilkes, Manish Shah, Barbara Ma, Scott T. Tagawa, David Nanus, Jones Nauseef, Olivier Elemento, Juan Miguel Mosquera, Cora N. Sternberg
Publikováno v:
Cancer Research. 83:2143-2143
CUP is a relatively common diagnosis that accounts for 3-9% of all cancers. The prognosis is poor with median survival of approximately 9 months. The identification of the primary tumor and therapy targets could improve the survival of these patients
Autor:
Zoia Antysheva, Daria Kiriy, Anton Sivkov, Alexander Sarachackov, Alexandra Boyko, Naira Samarina, Nara Shin, Jessica H. Brown, Ivan Kozlov, Viktor Svekolkin, Alexander Bagaev, Nathan Fowler, Nikita Kotlov
Publikováno v:
Cancer Research. 83:5405-5405
The ability to locate a tumor primary site for patients with a cancer of unknown primary (CUP) is a major obstacle in providing personalized therapeutic options and access to clinical trials. Despite the recent use of molecular-based tools to identif
Autor:
Daria Kiriy, Dmitry Tychinin, Nikita Kotlov, Olga Kudryashova, Anastasia Nikitina, Andrey Tyshevich, Naira Samarina, Ksenia Demina, Sandrine Degryse, Susan Raju Paul, Mark Poznansky, Krystle Lang Kuhs, James S. Lewis, Robert L. Ferris, Xiaowei Wang, Alexander Bagaev, Nathan Fowler, Lori Wirth, Daniel Faden
Publikováno v:
Cancer Research. 82:3823-3823
Human papillomavirus (HPV)-associated Head and Neck Squamous Cell Carcinoma (HPV+HNSCC) is now the most common HPV-associated malignancy in the United States. Current treatments can be associated with severe side-effects or lack of efficacy yet progn
Autor:
Ivan Valiev, Nikita Kotlov, Anna Belozerova, Aleksandra Lopareva, Anna Butusova, Naira Samarina, Alexandra Boiko, Sandrine Degryse, Lecia Sequist, Mari Mino-Kenudson, Nathan Fowler, Aleksander Bagaev, Michael Lanuti, Ibiayi Dagogo-Jack
Publikováno v:
Cancer Research. 82:5172-5172
In non-small cell lung cancer (NSCLC), likelihood of cure is heavily influenced by stage at diagnosis. In contrast to stage I where surgery achieves cure for >70% of patients, the majority of patients with stage II NSCLC will develop recurrent diseas
Autor:
Sandipto Sarkar, Prashant V. Thakkar, Rhonda K. Yantiss, Sandrine Degryse, Alexander Bagaev, Nathan Fowler, Olga Kudryashova, Svetlana Podsvirova, Naira Samarina, Dmitry Tychinin, Daria Melikhova, Manish A. Shah, Felix Frenkel
Publikováno v:
Cancer Research. 81:3182-3182
Gastric Cancer (GC) is the second leading cause of cancer-related mortality (9.7% of the total) and most patients with advanced disease will die within one year of diagnosis. GC is histologically classified into intestinal, diffuse and the mixed type
Autor:
Zoya Antysheva, Andrew P. South, Nathan Fowler, Sandrine Degryse, Adam Luginbuhl, Sanket Kumar Shukla, Alban Linnenbach, Larry Harshyne, Naira Samarina, Nikita Kotlov, Dina Antonova, Alexander Bagaev, Young J. Kim, Jennifer Johnson
Publikováno v:
Cancer Research. 81:1441-1441
Nivolumab, a PD-1 inhibitor, has variable response rates in patients and is not fully characterized in treatment-naïve patients. Here, we describe exploratory analyses of immune-related gene expression in squamous cell carcinoma of the head and neck