Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Naira M. Ayvazyan"'
Autor:
Sara Vaz, Luis A. Pardo, Naira Movsisyan, Joana C Macedo, Narine A. Ghazaryan, Elsa Logarinho, Naira M. Ayvazyan
Publikováno v:
Молекулярная биология. 55:468-477
Macrovipera lebetina obtusa (MLO) is a venomous snake endemic to Middle East. Here we describe the therapeutic potential of the MLO snake venom. In S-180 sarcoma-bearing mouse model, we showed that the MLO snake venom inhibits tumour growth by 50%. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d37971891b771798e15f40958d7c8f6
https://doi.org/10.31857/s0026898421030071
https://doi.org/10.31857/s0026898421030071
Publikováno v:
The Journal of Membrane Biology. 253:609-616
It is known that snake venoms are a complex of enzymes and proteins and the interaction of different venom components with the membranes could be significantly enhanced in course of their action in an orchestra. The aim of the proposed investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1053df8c5f2b1d77658c171ff57fb6
https://doi.org/10.1007/s00232-020-00144-z
https://doi.org/10.1007/s00232-020-00144-z
Autor:
Aram A. Shahinyan, Armen H. Poghosyan, Naira M. Ayvazyan, Gayane Kirakosyan, Garegin A. Papoian, Yevgeni Sh. Mamasakhlisov
Publikováno v:
Journal of Molecular Modeling. 27
Microsecond timescale explicit-solvent atomistic simulations were carried out to investigate how anionic surfactants modulate protein structure and dynamics. We found that lysozyme undergoes near-complete denaturation at the high concentration (> 0.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f318ca4acafc7d135e524a35644eefa5
https://doi.org/10.1007/s00894-021-04882-2
https://doi.org/10.1007/s00894-021-04882-2
Autor:
Rustam H. Ziganshin, Igor Ivanov, V. V. Ryabinin, Elena V. Kryukova, Naira M. Ayvazyan, Vladislav G. Starkov, V. I. Tsetlin, T. V. Andreeva, A. S. Potapenko, Yu. N. Utkin
Publikováno v:
Доклады Академии наук. 488:567-570
Four dimeric disintegrins were isolated from the venom of the steppe viper V. ursinii using liquid chromatography. Disintegrins prevented adhesion of MCF7 cells to fibronectin, which indicates their interaction with integrin receptors of the V1 type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::808d5707f697cf99d8a1614a0296ad33
https://doi.org/10.31857/s0869-56524885567-570
https://doi.org/10.31857/s0869-56524885567-570
Publikováno v:
Drug Discovery Today. 24:1968-1984
The neuromuscular junction (NMJ) is the principal site for the translation of motor neurochemical signals to muscle activity. Therefore, the release and sensing machinery of acetylcholine (ACh) along with muscle contraction are two of the main target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0807e2d8be93ba45471daa024008043b
https://doi.org/10.1016/j.drudis.2019.06.012
https://doi.org/10.1016/j.drudis.2019.06.012
Autor:
Saak V. Ovsepian, Vasilis Ntziachristos, Valerie B. O'Leary, Naira M. Ayvazyan, Ahmed Al-Sabi, James Oliver Dolly
Publikováno v:
Pharmacology & Therapeutics. 193:135-155
Synaptic transmission is a fundamental neurobiological process enabling exchange of signals between neurons as well as neurons and their non-neuronal effectors. The complex molecular machinery of the synaptic vesicle cycle and transmitter release has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbbf4e8f7e64cf3b8ab73b7da9162e5
https://doi.org/10.1016/j.pharmthera.2018.08.016
https://doi.org/10.1016/j.pharmthera.2018.08.016
Autor:
Armen H, Poghosyan, Aram A, Shahinyan, Gayane R, Kirakosyan, Naira M, Ayvazyan, Yevgeni S, Mamasakhlisov, Garegin A, Papoian
Publikováno v:
Journal of molecular modelingReferences. 27(9)
Microsecond timescale explicit-solvent atomistic simulations were carried out to investigate how anionic surfactants modulate protein structure and dynamics. We found that lysozyme undergoes near-complete denaturation at the high concentration ( 0.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::798972a0007de7450fc7ec940ca93c3c
https://pubmed.ncbi.nlm.nih.gov/34432183
https://pubmed.ncbi.nlm.nih.gov/34432183
Autor:
Naira M. Ayvazyan, T. Gevorgyan, L. A. Ghulikyan, Gayane Kirakosyan, M. Petrosyan, A. Hovhannisyan
Publikováno v:
IFMBE Proceedings ISBN: 9783030318659
The toxicity of the synthesized nanoparticles (NPs) by various physicochemical methods is one of the main problems for their application. NPs synthesized using plant extracts are less toxic than other methods of their congregation, so, in this regard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b497ab22ba1cb8503b1eeb8cad584ece
https://doi.org/10.1007/978-3-030-31866-6_101
https://doi.org/10.1007/978-3-030-31866-6_101
Autor:
L. A. Ghulikyan, Naira M. Ayvazyan, S. Ginosyan, Garri Chilingaryan, S. Tiratsuyan, Hovakim Grabski
Publikováno v:
IFMBE Proceedings ISBN: 9783030318659
The present study was conducted to evaluate the effect of artemisinins’ on the level of lipid peroxidation (LPO), spontaneous chemiluminescence of the S-180 sarcoma homogenate and to study the nature of the interaction with canonical and non-canoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee7ef32a778c2e0e864309dc2c7adb9
https://doi.org/10.1007/978-3-030-31866-6_97
https://doi.org/10.1007/978-3-030-31866-6_97
Autor:
V. I. Tsetlin, Elena V. Kryukova, T. V. Andreeva, Igor Ivanov, Yu. N. Utkin, A. S. Potapenko, V. V. Ryabinin, Naira M. Ayvazyan, Vladislav G. Starkov, Rustam H. Ziganshin
Publikováno v:
Doklady. Biochemistry and biophysics. 488(1)
Four dimeric disintegrins were isolated from the venom of the steppe viper V. ursinii using liquid chromatography. Disintegrins prevented adhesion of MCF7 cells to fibronectin, which indicates their interaction with integrin receptors of the αVβ1 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178c47ae468db6e1b75ffe9bed0c9299
https://pubmed.ncbi.nlm.nih.gov/31768855
https://pubmed.ncbi.nlm.nih.gov/31768855