Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Naiqi Zhang"'
Autor:
Wuqing Huang, Xi Yang, Naiqi Zhang, Keyuan Chen, Jun Xiao, Zhihuang Qiu, Sujun You, Ziting Gao, Jianguang Ji, Liangwan Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116710- (2024)
PDE5 inhibitors was reported to play a protective role in both regulating lipid metabolism and reducing heart failure (HF). This study aimed to clarify the effectiveness of PDE5 inhibitors against hyperlipidemia-related HF by combining evidence from
Externí odkaz:
https://doaj.org/article/1c0e16c581554bfbaaee7a648c56d577
Publikováno v:
Food Science and Human Wellness, Vol 12, Iss 5, Pp 1861-1871 (2023)
Docosahexaenoic acid (DHA; 22n-6) possesses multiple biological functions, including antioxidant activity and ameliorating hypertriglyceridemia. However, the application of DHA has been limited due to poor aqueous solubility and susceptible to oxidat
Externí odkaz:
https://doaj.org/article/12dc60b073cc46a788797ef0033f0a24
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104859- (2023)
Summary: Background: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the can
Externí odkaz:
https://doaj.org/article/d2be7e873f4a4e4ea07882cadf65ed21
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Individuals with a family history of colorectal cancer (CRC) are at a high risk of developing CRC. Preclinical studies suggest that the anti-malaria drug proguanil and atovaquone might play a role in preventing CRC, but population
Externí odkaz:
https://doaj.org/article/7bfd6cf4686242eeaab2b445c3730f36
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104432- (2023)
Summary: Background: Mitochondrial dysfunction is a hallmark of cancer. However, it is unclear whether it is a cause of cancer. This two-sample Mendelian randomization (MR) analyses, uses genetic instruments to proxy the exposure of mitochondrial dys
Externí odkaz:
https://doaj.org/article/4d91f962a85d47ca894e7de6cfe3357d
Autor:
Xinliang Wang, Qingxiao Su, Zhiyan Dou, Xue Zhao, Naiqi Zhang, Bo Yu, Yuxue Wang, Zanhua Rong
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: To observe the changes of autophagy-related protein levels in peripheral blood lymphocytes before and after sirolimus treatment in children with systemic lupus erythematosus (SLE).Methods: Children with SLE were randomly divided into two
Externí odkaz:
https://doaj.org/article/6733372d8a1b47579937f9406ecadd5f
Publikováno v:
European Journal of Preventive Cardiology. 30:358-366
To assess the association of genetically-predicted lipid traits and lipid-modification via licensed or investigational targets with heart failure (HF).Two-sample Mendelian randomization (MR) study was conducted using summary-level genome-wide associa
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
AimPolypharmacy is becoming a global health problem. The aims of this study were to evaluate the temporal trends in the prevalence of polypharmacy in Sweden and to explore polypharmacy disparities by age, gender, education, and immigration status.Met
Externí odkaz:
https://doaj.org/article/0930ecea08d3486c81e31e1996d0a9b4
Publikováno v:
Cancers; Volume 14; Issue 23; Pages: 5905
Individuals with a family history of colorectal cancer (CRC) are at a high risk of developing CRC. Preclinical and population-based evidence suggests that selective serotonin reuptake inhibitors (SSRIs) might play a role in preventing CRC. We perform
Publikováno v:
SSRN Electronic Journal.
Individuals with a family history of colorectal cancer (CRC) are at a high risk of developing CRC. Preclinical and population-based evidence suggests that selective serotonin reuptake inhibitors (SSRIs) might play a role in preventing CRC. We perform